CaV1.3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer.
Abbreviations
Aberrant Intracellular Calcium
Androgen Deprivation Therapy
Androgen Deprivation Therapy (ADT)
Androgen Receptor (AR)
CACNA1D
CaV1.3
Calcium (Ca2+)
Calcium Channel Blocker (CCB)
Castrate Resistant Prostate Cancer (CRPC)
Cellular Invasion and Migration (CIM)
Colony Formation Assay (CFA)
Cytosolic Calcium (Cac2+)
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH)
Immunofluorescence (IF)
Intracellular Calcium (Cai2+)
Log2 fold-change (LogFC)
Multiple Comparison Test (MCT)
Principal Components Analysis (PCA)
Prostate Cancer
Prostate Cancer (PCa)
Quality Control (QC)
Short Tandem Array (STR)
SiRNA Control (sictr)
Store Operated Calcium Entry (SOCE)
Store Operated Current (SOC)
Store operated calcium entry
Thapsigargin (Tg)
Tumour Microarrays (TMA)
Voltage Gated Calcium Channels (VGCC)
siRNA CaV1.3 (SiCaV1.3)
Journal
Cell calcium
ISSN: 1532-1991
Titre abrégé: Cell Calcium
Pays: Netherlands
ID NLM: 8006226
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
received:
21
09
2021
revised:
24
01
2022
accepted:
06
02
2022
pubmed:
23
2
2022
medline:
3
5
2022
entrez:
22
2
2022
Statut:
ppublish
Résumé
Androgen deprivation therapy (ADT) is the main treatment for advanced prostate cancer (PCa) but resistance results in progression to terminal castrate resistant PCa (CRPC), where there is an unmet therapeutic need. Aberrant intracellular calcium (Ca
Identifiants
pubmed: 35193095
pii: S0143-4160(22)00029-X
doi: 10.1016/j.ceca.2022.102554
pii:
doi:
Substances chimiques
Androgen Antagonists
0
Androgens
0
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
102554Informations de copyright
Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved.