Effects of fatty acid metabolites on nocturia.
Amides
/ administration & dosage
Animals
CLOCK Proteins
/ genetics
Circadian Rhythm
Disease Models, Animal
Docosahexaenoic Acids
/ administration & dosage
Ethanolamines
/ administration & dosage
Fatty Acids
/ administration & dosage
Injections, Intraperitoneal
Linoleic Acids, Conjugated
/ administration & dosage
Male
Mice, Inbred C57BL
Nocturia
/ blood
Palmitic Acids
/ administration & dosage
Photoperiod
Urinary Bladder
/ pathology
Urination
/ genetics
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
23 02 2022
23 02 2022
Historique:
received:
10
12
2021
accepted:
11
02
2022
entrez:
24
2
2022
pubmed:
25
2
2022
medline:
23
3
2022
Statut:
epublish
Résumé
Dysregulation of circadian rhythm can cause nocturia. Levels of fatty acid metabolites, such as palmitoylethanolamide (PEA), 9-hydroxy-10E,12Z-octadecadienoic acid (9-HODE), and 4-hydroxy-5E,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid (4-HDoHE), are higher in the serum of patients with nocturia; however, the reason remains unknown. Here, we investigated the circadian rhythm of fatty acid metabolites and their effect on voiding in mice. WT and Clock mutant (Clock
Identifiants
pubmed: 35197540
doi: 10.1038/s41598-022-07096-5
pii: 10.1038/s41598-022-07096-5
pmc: PMC8866436
doi:
Substances chimiques
Amides
0
Ethanolamines
0
Fatty Acids
0
Linoleic Acids, Conjugated
0
Palmitic Acids
0
9-hydroxy-10,12-octadecadienoic acid
15514-85-9
Docosahexaenoic Acids
25167-62-8
palmidrol
6R8T1UDM3V
CLOCK Proteins
EC 2.3.1.48
Clock protein, mouse
EC 2.3.1.48
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3050Informations de copyright
© 2022. The Author(s).
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