Structure-function relationships and modifications of cardiac sarcoplasmic reticulum Ca2+-transport.
Journal
Physiological research
ISSN: 1802-9973
Titre abrégé: Physiol Res
Pays: Czech Republic
ID NLM: 9112413
Informations de publication
Date de publication:
30 12 2021
30 12 2021
Historique:
entrez:
24
2
2022
pubmed:
25
2
2022
medline:
5
4
2022
Statut:
ppublish
Résumé
Sarcoplasmic reticulum (SR) is a specialized tubular network, which not only maintains the intracellular concentration of Ca2+ at a low level but is also known to release and accumulate Ca2+ for the occurrence of cardiac contraction and relaxation, respectively. This subcellular organelle is composed of several phospholipids and different Ca2+-cycling, Ca2+-binding and regulatory proteins, which work in a coordinated manner to determine its function in cardiomyocytes. Some of the major proteins in the cardiac SR membrane include Ca2+-pump ATPase (SERCA2), Ca2+-release protein (ryanodine receptor), calsequestrin (Ca2+-binding protein) and phospholamban (regulatory protein). The phosphorylation of SR Ca2+-cycling proteins by protein kinase A or Ca2+-calmodulin kinase (directly or indirectly) has been demonstrated to augment SR Ca2+-release and Ca2+-uptake activities and promote cardiac contraction and relaxation functions. The activation of phospholipases and proteases as well as changes in different gene expressions under different pathological conditions have been shown to alter the SR composition and produce Ca2+-handling abnormalities in cardiomyocytes for the development of cardiac dysfunction. The post-translational modifications of SR Ca2+ cycling proteins by processes such as oxidation, nitrosylation, glycosylation, lipidation, acetylation, sumoylation, and O GlcNacylation have also been reported to affect the SR Ca2+ release and uptake activities as well as cardiac contractile activity. The SR function in the heart is also influenced in association with changes in cardiac performance by several hormones including thyroid hormones and adiponectin as well as by exercise-training. On the basis of such observations, it is suggested that both Ca2+-cycling and regulatory proteins in the SR membranes are intimately involved in determining the status of cardiac function and are thus excellent targets for drug development for the treatment of heart disease.
Identifiants
pubmed: 35199536
pii: 934805
doi: 10.33549/physiolres.934805
pmc: PMC9054189
Substances chimiques
Calcium
SY7Q814VUP
Types de publication
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
S443-S470Références
Circ Res. 2020 Feb 14;126(4):417-435
pubmed: 31805819
Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):4507-4512
pubmed: 29632175
Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a003996
pubmed: 20961976
Circ Res. 2017 Jun 9;120(12):1969-1993
pubmed: 28596175
J Mol Cell Cardiol. 1976 Sep;08(9):661-7
pubmed: 972403
Subcell Biochem. 2018;87:229-258
pubmed: 29464562
Cardiology. 1970;55(3):178-91
pubmed: 4254034
J Biol Chem. 2003 Nov 7;278(45):44230-7
pubmed: 12941958
JAMA. 2004 Apr 14;291(14):1730-7
pubmed: 15082700
Circulation. 2019 Feb 12;139(7):949-964
pubmed: 30586718
Mitochondrion. 2012 Jul;12(4):449-58
pubmed: 22709542
Mol Cell. 2000 Jul;6(1):11-22
pubmed: 10949023
Biochim Biophys Acta. 1996 Jul 18;1275(1-2):111-7
pubmed: 8688442
Circ Heart Fail. 2020 Jul;13(7):e006935
pubmed: 32635769
Biophys J. 1994 Jul;67(1):190-6
pubmed: 7918987
Traffic. 2008 Jul;9(7):1044-9
pubmed: 18266914
Nature. 1966 Aug 6;211(5049):646-7
pubmed: 5968741
J Appl Physiol (1985). 2014 Sep 1;117(5):544-55
pubmed: 24876362
Science. 2002 Aug 16;297(5584):1193-6
pubmed: 12183633
Curr Opin Pharmacol. 2005 Apr;5(2):129-34
pubmed: 15780820
Cell Calcium. 2009 Sep;46(3):219-25
pubmed: 19692123
Adv Cyclic Nucleotide Res. 1975;5:453-72
pubmed: 165680
Biochem J. 1991 Nov 1;279 ( Pt 3):711-8
pubmed: 1953663
Biochem J. 2008 Apr 15;411(2):343-9
pubmed: 18035970
Cell Calcium. 2002 Nov-Dec;32(5-6):279-305
pubmed: 12543090
J Biol Chem. 2011 Jun 10;286(23):20591-9
pubmed: 21515674
Curr Med Chem. 2012;19(32):5459-66
pubmed: 22876923
Annu Rev Biophys Bioeng. 1975;4(00):377-404
pubmed: 125558
FEBS Lett. 1990 Oct 1;271(1-2):169-77
pubmed: 2226801
J Biol Chem. 1994 Apr 29;269(17):13021-9
pubmed: 8175722
Circ Res. 2005 May 13;96(9):1006-13
pubmed: 15817886
J Biol Chem. 1999 Jan 22;274(4):2556-62
pubmed: 9891028
Circ Res. 2014 Jan 3;114(1):101-8
pubmed: 24065463
J Mol Cell Cardiol. 2016 Mar;92:82-92
pubmed: 26827896
Circ Heart Fail. 2014 Jan;7(1):194-202
pubmed: 24297688
Biochem Soc Trans. 2005 Dec;33(Pt 6):1378-81
pubmed: 16246123
J Biol Chem. 2007 Dec 21;282(51):37205-14
pubmed: 17908690
J Clin Invest. 1998 Apr 1;101(7):1385-93
pubmed: 9525981
J Physiol. 2017 May 15;595(10):3041-3051
pubmed: 28303572
Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1219-23
pubmed: 17227845
Crit Care Med. 2017 Apr;45(4):e399-e408
pubmed: 27648519
Sci Rep. 2020 May 15;10(1):8076
pubmed: 32415205
Circ Res. 1994 Aug;75(2):245-51
pubmed: 8033338
Basic Res Cardiol. 2020 Nov 30;115(6):74
pubmed: 33258101
J Mol Cell Cardiol. 2016 Dec;101:156-164
pubmed: 27585747
Biochem J. 1993 Nov 1;295 ( Pt 3):685-90
pubmed: 8240278
Cell. 2007 Dec 14;131(6):1047-58
pubmed: 18083096
Sci Rep. 2017 Jul 13;7(1):5328
pubmed: 28706255
J Mol Cell Cardiol. 2007 Sep;43(3):354-61
pubmed: 17689560
Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5040-5
pubmed: 12692302
Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2446-51
pubmed: 16461894
Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17867-72
pubmed: 17971438
Am J Physiol Heart Circ Physiol. 2019 Jun 1;316(6):H1323-H1331
pubmed: 30901276
Circulation. 2019 Jul 2;140(1):55-66
pubmed: 30982350
J Mol Cell Cardiol. 2000 Mar;32(3):453-64
pubmed: 10731444
J Biol Chem. 1994 Jan 14;269(2):1460-7
pubmed: 8166809
J Physiol. 2002 Jun 15;541(Pt 3):863-75
pubmed: 12068046
Circulation. 2019 Aug 20;140(8):681-693
pubmed: 31185731
Nature. 2011 Sep 07;477(7366):601-5
pubmed: 21900893
J Cell Mol Med. 2020 Sep;24(17):9627-9637
pubmed: 33460250
Am J Physiol. 1983 Jul;245(1):C1-14
pubmed: 6346892
J Mol Cell Cardiol. 2013 Feb;55:85-91
pubmed: 23085588
J Physiol. 1883 Jan;4(1):29-42.3
pubmed: 16991336
Am J Physiol. 1997 Jul;273(1 Pt 1):C1-6
pubmed: 9252436
Cardiovasc Res. 2009 Feb 15;81(3):429-38
pubmed: 18852252
J Biol Chem. 2003 Nov 28;278(48):47877-89
pubmed: 12975374
Biochem J. 2006 Apr 15;395(2):249-58
pubmed: 16402920
BMB Rep. 2013 May;46(5):237-43
pubmed: 23710633
Cardiovasc Res. 2008 Jan 15;77(2):265-73
pubmed: 18006443
Cardiovasc Res. 2003 Nov 1;60(2):347-54
pubmed: 14613864
J Physiol. 2009 Jul 1;587(Pt 13):3071-9
pubmed: 19403606
Circ Res. 2013 Apr 26;112(9):1234-43
pubmed: 23524588
Cardiovasc Res. 2008 Apr 1;78(1):116-22
pubmed: 18222959
J Biol Chem. 2012 Sep 14;287(38):31624-32
pubmed: 22822064
J Mol Cell Cardiol. 1999 Jun;31(6):1299-314
pubmed: 10371704
Stem Cells. 2019 Jan;37(1):54-64
pubmed: 30353632
J Gen Physiol. 2017 Dec 4;149(12):1065-1089
pubmed: 29122978
Diabetes Res Clin Pract. 2001 Dec;54 Suppl 2:S3-9
pubmed: 11733104
Can J Physiol Pharmacol. 2019 Sep;97(9):815-819
pubmed: 30913398
Methods Enzymol. 1983;102:261-78
pubmed: 6316079
Subcell Biochem. 2018;87:329-352
pubmed: 29464565
Biochem Biophys Res Commun. 2003 Apr 4;303(2):676-84
pubmed: 12659872
J Appl Physiol (1985). 2009 Oct;107(4):1105-12
pubmed: 19679745
Adv Exp Med Biol. 2020;1131:321-336
pubmed: 31646516
Life Sci. 2013 Mar 28;92(11):657-63
pubmed: 23000101
Cardiovasc Res. 2003 Jan;57(1):20-7
pubmed: 12504810
Heart Fail Rev. 2020 May;25(3):523-535
pubmed: 31701344
J Biol Chem. 2000 Dec 1;275(48):38073-80
pubmed: 10970890
Endocrinology. 2015 Jul;156(7):2667-77
pubmed: 25961840
Nat Commun. 2015 Jun 12;6:7229
pubmed: 26068603
J Mol Cell Cardiol. 2004 Aug;37(2):417-29
pubmed: 15276012
Biochim Biophys Acta. 2012 Apr;1822(4):607-14
pubmed: 22155497
Diabetes. 2004 Dec;53(12):3201-8
pubmed: 15561951
Circulation. 2005 Aug 2;112(5):683-90
pubmed: 16043643
Am J Physiol. 1992 Mar;262(3 Pt 2):H868-74
pubmed: 1313649
Acta Physiol (Oxf). 2010 Aug;199(4):425-39
pubmed: 20353489
Front Biosci. 2008 Jan 01;13:356-68
pubmed: 17981553
Circulation. 2001 Feb 27;103(8):1089-94
pubmed: 11222471
Prog Biophys Mol Biol. 1968;18:123-83
pubmed: 4894870
Biochem Biophys Res Commun. 2000 Jul 14;273(3):920-7
pubmed: 10891348
Biochim Biophys Acta. 2014 Mar;1838(3):766-75
pubmed: 24099739
J Mol Cell Cardiol. 2001 Jun;33(6):1053-63
pubmed: 11444913
Biochemistry. 1979 Nov 13;18(23):5150-7
pubmed: 227448
Mol Cell Biol. 2005 Apr;25(8):3261-75
pubmed: 15798210
Biochimie. 2012 Oct;94(10):2143-9
pubmed: 22796520
Circ Res. 2009 Mar 27;104(6):720-3
pubmed: 19265039
Am J Physiol Heart Circ Physiol. 2017 Jun 1;312(6):H1105-H1109
pubmed: 28389603
J Mol Cell Cardiol. 2009 Aug;47(2):180-7
pubmed: 19328205
Biochem Biophys Res Commun. 2009 Dec 25;390(4):1389-94
pubmed: 19896466
Cardiovasc Res. 2005 Jan 1;65(1):177-86
pubmed: 15621045
PLoS One. 2013 Apr 11;8(4):e60931
pubmed: 23593350
Adv Enzymol Relat Areas Mol Biol. 1967;29:259-320
pubmed: 4881885
Physiol Rev. 2017 Jan;97(1):227-252
pubmed: 27881552
Biochem Biophys Res Commun. 1962 Apr 3;7:132-6
pubmed: 14036081
Nat Rev Mol Cell Biol. 2003 Jul;4(7):566-77
pubmed: 12838339
Physiol Rev. 2007 Apr;87(2):457-506
pubmed: 17429038
J Biol Chem. 2005 Feb 4;280(5):3500-6
pubmed: 15569689
J Cardiovasc Pharmacol. 2013 Aug;62(2):143-53
pubmed: 23609327
Curr Top Membr. 2010;66:91-113
pubmed: 21666757
J Cell Biol. 2001 Sep 3;154(5):1059-67
pubmed: 11535622
Can J Physiol Pharmacol. 1986 Nov;64(11):1368-75
pubmed: 3024783
J Biol Chem. 2000 Dec 15;275(50):39555-68
pubmed: 11007777
Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17797-802
pubmed: 20876116
J Mol Cell Cardiol. 1994 Sep;26(9):1145-54
pubmed: 7815458
Am J Physiol. 1983 Jun;244(6):E528-35
pubmed: 6134470
Biochem Biophys Res Commun. 2007 Oct 12;362(1):1-4
pubmed: 17706594
J Physiol. 2020 Jul;598(14):2817-2834
pubmed: 32115705
J Muscle Res Cell Motil. 2017 Feb;38(1):37-45
pubmed: 28653141
Nature. 2007 Jul 5;448(7149):78-82
pubmed: 17611541
Int J Biochem Cell Biol. 2012 May;44(5):801-7
pubmed: 22343412
Endocrinology. 2000 Jun;141(6):2139-44
pubmed: 10830301
Biochemistry. 2005 Oct 4;44(39):13071-81
pubmed: 16185075
Science. 1989 May 19;244(4906):800-3
pubmed: 2543067
Acta Physiol (Oxf). 2010 Jan;198(1):71-9
pubmed: 19681768
Cardiovasc Res. 2021 Jan 1;117(1):149-161
pubmed: 32053184
J Appl Physiol (1985). 2004 Jan;96(1):189-94
pubmed: 12972445
J Mol Cell Cardiol. 2010 Jul;49(1):58-69
pubmed: 20025885
Adv Exp Med Biol. 2020;1131:281-320
pubmed: 31646515
J Neuromuscul Dis. 2016 Nov 29;3(4):443-453
pubmed: 27911331
Can J Physiol Pharmacol. 1980 Apr;58(4):360-7
pubmed: 6446372
Biochim Biophys Acta. 2013 Nov;1833(11):2542-59
pubmed: 23770047
Biochem Soc Trans. 2015 Jun;43(3):377-83
pubmed: 26009179
Annu Rev Physiol. 1979;41:473-84
pubmed: 373601
J Mol Cell Cardiol. 2008 Feb;44(2):361-9
pubmed: 18164028
Annu Rev Biophys Bioeng. 1972;1:191-210
pubmed: 4346304
Basic Res Cardiol. 1997;92 Suppl 1:17-24
pubmed: 9202840
Adipocyte. 2014 Jan 1;3(1):10-8
pubmed: 24575364
Cardiovasc Res. 2011 Apr 1;90(1):57-67
pubmed: 21113058
Nature. 2014 Apr 24;508(7497):531-5
pubmed: 24670661
Arch Biochem Biophys. 1971 Jun;144(2):529-40
pubmed: 4328159
Cardiovasc Res. 2022 May 6;118(6):1479-1491
pubmed: 34152414
Circulation. 2020 Sep 22;142(12):1159-1172
pubmed: 32683896
Obesity (Silver Spring). 2006 Feb;14 Suppl 1:9S-15S
pubmed: 16642957
Eur Heart J. 1984 Dec;5 Suppl F:323-8
pubmed: 6152423
Exp Mol Med. 2020 Dec;52(12):1908-1925
pubmed: 33288873
Biochim Biophys Acta. 2009 Jun;1793(6):941-6
pubmed: 19010358
Physiol Rev. 1970 Jan;50(1):63-158
pubmed: 4243851
J Biol Chem. 2013 Mar 8;288(10):6881-9
pubmed: 23341466
Heart Rhythm. 2011 May;8(5):784-7
pubmed: 21111063
Rev Physiol Biochem Pharmacol. 2016;171:39-62
pubmed: 27251471
J Mol Cell Cardiol. 2016 Feb;91:81-91
pubmed: 26743715
Physiol Rev. 2007 Apr;87(2):593-658
pubmed: 17429043
Fed Proc. 1969 Sep-Oct;28(5):1657-62
pubmed: 5811738
Am J Physiol Heart Circ Physiol. 2013 Jul 1;305(1):H114-23
pubmed: 23624624
Genomics. 1993 Aug;17(2):507-9
pubmed: 8406504
Circulation. 2005 Jun 28;111(25):3420-8
pubmed: 15967848
J Appl Physiol (1985). 2011 Jul;111(1):157-62
pubmed: 21493720
Annu Rev Plant Biol. 2010;61:593-620
pubmed: 20192754
J Physiol. 2017 Jun 15;595(12):4009-4017
pubmed: 28332202
Cold Spring Harb Perspect Biol. 2011 Mar 01;3(3):
pubmed: 21421925
J Biol Chem. 2013 Oct 25;288(43):31358-62
pubmed: 24025332
J Biol Chem. 2003 Mar 14;278(11):9570-5
pubmed: 12645548
Pflugers Arch. 2021 Mar;473(3):547-556
pubmed: 33474637
Adv Exp Med Biol. 2020;1131:337-370
pubmed: 31646517
Nat Med. 2009 Nov;15(11):1281-8
pubmed: 19881492
Physiol Rev. 1978 Jan;58(1):1-79
pubmed: 23557
Circ Res. 2007 Mar 30;100(6):761-3
pubmed: 17395881
Acta Physiol (Oxf). 2019 Jul;226(3):e13261
pubmed: 30710413
Physiol Rev. 1998 Oct;78(4):921-47
pubmed: 9790566
J Physiol. 2013 Dec 1;591(23):6053-68
pubmed: 24127619
Am Heart J. 1963 Mar;65:404-11
pubmed: 13937796
Cell Res. 2016 Oct;26(10):1073-1074
pubmed: 27608934
Nature. 1962 Apr 28;194:378-9
pubmed: 13888992
Trends Biochem Sci. 2003 Dec;28(12):671-8
pubmed: 14659699
Circulation. 2011 Oct 4;124(14):1537-47
pubmed: 21900086
Arch Biochem Biophys. 1971 May;144(1):66-77
pubmed: 4256091
Biochem Biophys Res Commun. 2015 Aug 14;464(1):133-9
pubmed: 26141232
Nat Rev Mol Cell Biol. 2003 Jul;4(7):517-29
pubmed: 12838335
Physiol Genomics. 2013 Jan 7;45(1):17-25
pubmed: 23132757
Circ Res. 1991 Aug;69(2):266-76
pubmed: 1830516
Nature. 2004 Sep 16;431(7006):350-5
pubmed: 15372042
Annu Rev Biochem. 2004;73:269-92
pubmed: 15189143
Am J Physiol. 1999 Sep;277(3):C384-91
pubmed: 10484325
Circ Res. 2014 Feb 14;114(4):706-16
pubmed: 24526676
J Biol Chem. 1987 Mar 15;262(8):3768-74
pubmed: 3029125
Annu Rev Physiol. 1976;38:293-313
pubmed: 769656
J Am Heart Assoc. 2013 Apr 23;2(2):e000078
pubmed: 23612897
Prog Biophys Mol Biol. 2004 May;85(1):33-69
pubmed: 15050380
J Am Heart Assoc. 2018 Jun 21;7(13):
pubmed: 29929992
Am J Physiol Heart Circ Physiol. 2009 Aug;297(2):H576-82
pubmed: 19502553
Int J Mol Sci. 2019 Aug 16;20(16):
pubmed: 31426283
J Biol Chem. 1988 May 25;263(15):6941-4
pubmed: 2966798
Nature. 2002 Aug 8;418(6898):605-11
pubmed: 12167852
J Clin Invest. 1971 May;50(5):1019-27
pubmed: 4324071
Proc Natl Acad Sci U S A. 1989 Apr;86(8):2966-70
pubmed: 2523077
Cell Calcium. 2020 Sep;90:102242
pubmed: 32574906
J Cell Sci. 2016 Dec 1;129(23):4388-4398
pubmed: 27802169
Int J Mol Sci. 2017 May 10;18(5):
pubmed: 28489021
Med Chem. 2016;12(2):177-83
pubmed: 26411599
J Physiol Biochem. 2003 Mar;59(1):51-60
pubmed: 12903905
Annu Rev Neurosci. 2008;31:563-90
pubmed: 18558867
J Gen Physiol. 1966 Mar;49(4):689-715
pubmed: 5943610
Circ Res. 1979 Feb;44(2):145-53
pubmed: 216502
J Mol Cell Cardiol. 2003 Jul;35(7):777-83
pubmed: 12818568
Heart Fail Rev. 2012 Sep;17(4-5):671-81
pubmed: 21850540
J Biol Chem. 1970 Sep 10;245(17):4508-18
pubmed: 4250726
Can J Cardiol. 1985 Nov-Dec;1(6):401-8
pubmed: 2944571
Am J Physiol. 1986 Nov;251(5 Pt 1):E515-23
pubmed: 2430466
PLoS One. 2012;7(12):e52617
pubmed: 23285113
Mol Cells. 2016 Feb;39(2):149-55
pubmed: 26674963
Plant Foods Hum Nutr. 2002 Winter;57(1):41-52
pubmed: 11855620
Am J Physiol Cell Physiol. 2008 Dec;295(6):C1561-8
pubmed: 19060297
Basic Res Cardiol. 1982 Mar-Apr;77(2):117-39
pubmed: 6284117
J Exp Biol. 2019 Apr 1;222(Pt 7):
pubmed: 30814295
Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20108-13
pubmed: 18077436
Adv Pharmacol. 2010;59:165-95
pubmed: 20933202
Ann N Y Acad Sci. 1974 Feb 18;227:527-36
pubmed: 4275124
Cell Metab. 2011 Aug 3;14(2):231-41
pubmed: 21803293
J Physiol. 2010 Feb 1;588(Pt 3):465-78
pubmed: 20008467
Circ Res. 2000 Dec 8;87(12):1087-94
pubmed: 11110764
J Biol Chem. 2000 Dec 15;275(50):39543-54
pubmed: 10956665
Gen Physiol Biophys. 1983 Oct;2(5):339-51
pubmed: 6236129
Mitochondrion. 2007 Feb-Apr;7(1-2):39-44
pubmed: 17280879
Genomics. 1997 Nov 1;45(3):541-53
pubmed: 9367679
FEBS Lett. 2010 May 17;584(10):1956-65
pubmed: 20214899
Mitochondrion. 2011 Jan;11(1):54-63
pubmed: 20654738
J Biol Chem. 2004 Dec 10;279(50):52382-9
pubmed: 15371420
Can J Physiol Pharmacol. 2006 May;84(5):509-21
pubmed: 16902596
Genes Dev. 2001 Nov 15;15(22):2967-79
pubmed: 11711432
Expert Opin Ther Targets. 2020 Jan;24(1):25-36
pubmed: 31869254
J Appl Physiol (1985). 2013 Jul 1;115(1):107-15
pubmed: 23640594
Circ Res. 2021 Jan 8;128(1):92-114
pubmed: 33092464
Am J Physiol. 1979 Dec;237(6):H713-9
pubmed: 517670
Biochimie. 1973;55(6):755-62
pubmed: 4797824
Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11389-94
pubmed: 26217001
PLoS One. 2013 Jul 01;8(7):e68924
pubmed: 23840903
Cardiovasc Res. 2001 Jun;50(3):495-508
pubmed: 11376625
Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9199-204
pubmed: 15201433
Biophys J. 1993 Aug;65(2):693-701
pubmed: 8218897
J Clin Invest. 1997 Oct 1;100(7):1742-9
pubmed: 9312172
Cardiovasc Res. 2001 Apr;50(1):24-33
pubmed: 11282075
Dev Biol. 2005 Oct 1;286(1):326-37
pubmed: 16153633
J Biol Chem. 1968 Jan 10;243(1):61-70
pubmed: 4229832
Can J Physiol Pharmacol. 1984 Jul;62(7):867-73
pubmed: 6238664
Physiol Rev. 1968 Oct;48(4):708-57
pubmed: 4879915
Z Naturforsch C Biosci. 1982 Jul-Aug;37(7-8):665-78
pubmed: 7136180
J Physiol. 2017 Jun 15;595(12):4001-4008
pubmed: 28181690
Muscle Nerve. 2007 Apr;35(4):430-42
pubmed: 17286271
Can J Physiol Pharmacol. 1977 Dec;55(6):1211-34
pubmed: 23210
Circ Res. 2017 Jul 7;121(2):181-195
pubmed: 28684623
J Cell Biol. 1962 Sep 1;14(3):389-400
pubmed: 19866605
Mol Cell Biol. 2005 Feb;25(4):1354-66
pubmed: 15684387
Nature. 2002 Jan 10;415(6868):198-205
pubmed: 11805843
Circulation. 2002 Jul 2;106(1):69-74
pubmed: 12093772
J Biol Chem. 1990 Jun 15;265(17):10118-24
pubmed: 2112542
J Cell Biol. 2004 Aug 16;166(4):537-48
pubmed: 15302852
Nat Rev Cardiol. 2020 Nov;17(11):732-747
pubmed: 32555383
FEBS Lett. 2002 Jul 31;524(1-3):225-9
pubmed: 12135771
Basic Res Cardiol. 2016 Jan;111(1):6
pubmed: 26659360
Am J Physiol Endocrinol Metab. 2013 Dec;305(12):E1436-43
pubmed: 24129398
Dev Growth Differ. 2001 Dec;43(6):717-23
pubmed: 11737152
FASEB J. 2019 Aug;33(8):8892-8904
pubmed: 31051095
Am J Physiol Heart Circ Physiol. 2012 Jun 1;302(11):H2190-210
pubmed: 22447942
J Cell Physiol. 2017 Sep;232(9):2348-2358
pubmed: 27966783
J Mol Cell Cardiol. 2012 Mar;52(3):520-5
pubmed: 22119802
Can J Physiol Pharmacol. 2015 Oct;93(10):843-54
pubmed: 25730320