MRI CNS Atrophy Pattern and the Etiologies of Progressive Ataxias.
CNS
MRI
ataxia
Journal
Tomography (Ann Arbor, Mich.)
ISSN: 2379-139X
Titre abrégé: Tomography
Pays: Switzerland
ID NLM: 101671170
Informations de publication
Date de publication:
08 02 2022
08 02 2022
Historique:
received:
09
11
2021
revised:
16
01
2022
accepted:
02
02
2022
entrez:
24
2
2022
pubmed:
25
2
2022
medline:
25
3
2022
Statut:
epublish
Résumé
MRI shows the three archetypal patterns of CNS volume loss underlying progressive ataxias in vivo, namely spinal atrophy (SA), cortical cerebellar atrophy (CCA) and olivopontocerebellar atrophy (OPCA). The MRI-based CNS atrophy pattern was reviewed in 128 progressive ataxias. A CNS atrophy pattern was identified in 91 conditions: SA in Friedreich's ataxia, CCA in 5 acquired and 72 (24 dominant, 47 recessive,1 X-linked) inherited ataxias, OPCA in Multi-System Atrophy and 12 (9 dominant, 2 recessive,1 X-linked) inherited ataxias. The MRI-based CNS atrophy pattern may be useful for genetic assessment, identification of shared cellular targets, repurposing therapies or the enlargement of drug indications in progressive ataxias.
Identifiants
pubmed: 35202200
pii: tomography8010035
doi: 10.3390/tomography8010035
pmc: PMC8877967
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
423-437Références
Brain. 2014 Feb;137(Pt 2):402-10
pubmed: 24369383
BMC Neurol. 2018 Jan 9;18(1):3
pubmed: 29316893
Neurol India. 2021 Jan-Feb;69(1):217-218
pubmed: 33642310
Brain. 2015 Feb;138(Pt 2):276-83
pubmed: 25497598
Neurology. 2018 Nov 20;91(21):e1988-e1998
pubmed: 30381368
Neurol Sci. 2004 Jul;25(3):130-7
pubmed: 15300460
Ann Neurol. 2021 Oct;90(4):570-583
pubmed: 34435700
Cerebellum. 2015 Apr;14(2):128-32
pubmed: 25370748
Cerebellum. 2019 Dec;18(6):1098-1125
pubmed: 31267374
Neurology. 1993 Feb;43(2):318-25
pubmed: 8437696
J Clin Neurol. 2018 Jul;14(3):374-380
pubmed: 29971977
Ann Neurol. 2003 Feb;53(2):252-8
pubmed: 12557294
Pract Neurol. 2019 Jun;19(3):196-207
pubmed: 31048364
Neuroimage. 2008 Mar 1;40(1):19-25
pubmed: 18226551
Cerebellum Ataxias. 2015 Jul 07;2:8
pubmed: 26331051
J Neurol Neurosurg Psychiatry. 1994 Jan;57(1):51-7
pubmed: 8301305
Lancet Neurol. 2013 Jul;12(7):650-8
pubmed: 23707147
Radiology. 1990 Mar;174(3 Pt 1):693-6
pubmed: 2305051
Neuroradiology. 2021 Jul;63(7):983-999
pubmed: 33733696
Hum Genet. 2000 Aug;107(2):132-7
pubmed: 11030410
J Neurol. 2021 Sep;268(9):3337-3343
pubmed: 33666721
Neurol Sci. 2008 Oct;29 Suppl 3:311-3
pubmed: 18941720
Arch Neurol. 2005 Apr;62(4):666-70
pubmed: 15824270
Brain. 2018 Sep 1;141(9):2592-2604
pubmed: 30084953
Ann Neurol. 2020 Dec;88(6):1132-1143
pubmed: 32939785
Neurology. 2012 Jul 24;79(4):333-41
pubmed: 22744658
J Neurol. 2017 Jun;264(6):1118-1126
pubmed: 28478596
Brain. 2011 Jan;134(Pt 1):143-56
pubmed: 20952379
Brain. 2020 Sep 1;143(9):2673-2680
pubmed: 32851396
Acta Neurol Scand. 1998 Jul;98(1):55-9
pubmed: 9696528
Neurology. 2012 Oct 30;79(18):1898-907
pubmed: 23077007
Lancet Neurol. 2013 Jul;12(7):659-68
pubmed: 23707145
Brain. 2004 May;127(Pt 5):1172-81
pubmed: 14998916
Brain. 2020 Feb 1;143(2):480-490
pubmed: 32040566
Am J Hum Genet. 2000 Jul;67(1):229-35
pubmed: 10820125
Neurol Genet. 2021 Feb 3;7(2):e563
pubmed: 33898739
Mayo Clin Proc. 2017 Feb;92(2):292-305
pubmed: 28160876
Ann Neurol. 2017 Dec;82(6):892-899
pubmed: 29059497
Acta Neurol Scand. 2005 Mar;111(3):154-62
pubmed: 15691283
J Neurol Sci. 2009 Jun 15;281(1-2):93-8
pubmed: 19286195
Ann Neurol. 2018 Jun;83(6):1089-1095
pubmed: 29518281
Cerebellum. 2017 Aug;16(4):792-796
pubmed: 28386793
Am J Hum Genet. 2008 Jul;83(1):30-42
pubmed: 18571143
Brain. 1991 Aug;114 ( Pt 4):1559-73
pubmed: 1884166
Int Rev Neurobiol. 2018;143:109-162
pubmed: 30473193
Brain. 2017 Nov 1;140(11):2860-2878
pubmed: 29053796
Neurology. 2001 Sep 25;57(6):1043-9
pubmed: 11571332
Cerebellum. 2013 Dec;12(6):932-6
pubmed: 23912307
J Mov Disord. 2017 Sep;10(3):116-122
pubmed: 28782341
Eur J Radiol. 2019 Jan;110:187-192
pubmed: 30599859
Neurology. 2021 Mar 2;96(9):e1369-e1382
pubmed: 33495376
Continuum (Minneap Minn). 2019 Aug;25(4):1036-1054
pubmed: 31356292
Neurol Sci. 2019 Jul;40(7):1335-1342
pubmed: 30927137
Parkinsonism Relat Disord. 2020 Nov;80:58-64
pubmed: 32961395
J Neuroradiol. 2018 Sep;45(5):265-275
pubmed: 29920348
Neurol Genet. 2020 May 20;6(3):e440
pubmed: 32582864
J Neurol. 2019 Feb;266(2):533-544
pubmed: 30284037
Parkinsonism Relat Disord. 2019 Sep;66:220-223
pubmed: 31422002
Neuroradiology. 2020 Sep;62(9):1095-1103
pubmed: 32285148
Ital J Neurol Sci. 1995 Jun;16(5):303-8
pubmed: 8537218
Handb Clin Neurol. 2012;103:343-57
pubmed: 21827899
Cerebellum Ataxias. 2016 Oct 3;3:17
pubmed: 27729985
Eur J Neurol. 2014 Aug;21(8):1131-1136
pubmed: 24779923
Parkinsonism Relat Disord. 2021 Aug;89:120-127
pubmed: 34284285
Brain. 2020 Jun 1;143(6):e49
pubmed: 32428220
Radiology. 2002 May;223(2):371-8
pubmed: 11997539
Eur J Hum Genet. 2013 Jan;21(1):34-9
pubmed: 22669416
Neuroepidemiology. 2014;42(3):174-83
pubmed: 24603320
Neuroimage. 2008 Oct 15;43(1):10-9
pubmed: 18672073
Mov Disord. 2018 Jul;33(7):1056-1076
pubmed: 29756227
Cerebellum. 2008;7(2):101-5
pubmed: 18418679
Neuroradiology. 2021 Nov;63(11):1745-1746
pubmed: 34505181
Am J Hum Genet. 2016 Jun 2;98(6):1146-1158
pubmed: 27259050
AJNR Am J Neuroradiol. 1994 Oct;15(9):1721-6
pubmed: 7847220
Neuroimage. 2004 Jun;22(2):698-705
pubmed: 15193598
F1000Res. 2018 Jun 13;7:
pubmed: 29946432
AJR Am J Roentgenol. 1994 Jul;163(1):187-91
pubmed: 8010211