Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in

GATA1 TGF-β1 interleukin 8 local microinflammatory states megakaryocytes myelofibrosis proinflammatory cytokines systemic microinflammatory states

Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
30 01 2022
Historique:
received: 10 01 2022
revised: 27 01 2022
accepted: 27 01 2022
entrez: 25 2 2022
pubmed: 26 2 2022
medline: 5 4 2022
Statut: epublish

Résumé

Serum levels of inflammatory cytokines are currently investigated as prognosis markers in myelofibrosis, the most severe Philadelphia-negative myeloproliferative neoplasm. We tested this hypothesis in the

Identifiants

pubmed: 35204735
pii: biom12020234
doi: 10.3390/biom12020234
pmc: PMC8961549
pii:
doi:

Substances chimiques

Cytokines 0
GATA1 Transcription Factor 0
Gata1 protein, mouse 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NCI NIH HHS
ID : P01 CA108671
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL134684
Pays : United States
Organisme : NCI NIH HHS
ID : P01-CA108671
Pays : United States

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Auteurs

Maria Zingariello (M)

Department of Medicine, Campus Bio-Medico, 00128 Rome, Italy.

Paola Verachi (P)

Department of Biomedical and Neuromotorial Sciences, Alma Mater University, 40126 Bologna, Italy.

Francesca Gobbo (F)

Department of Biomedical and Neuromotorial Sciences, Alma Mater University, 40126 Bologna, Italy.
Department of Veterinary Medical Sciences, University of Bologna, 40126 Bologna, Italy.

Fabrizio Martelli (F)

National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.

Mario Falchi (M)

National Center HIV/AIDS Research, Istituto Superiore di Sanità, 00161 Rome, Italy.

Maria Mazzarini (M)

Department of Biomedical and Neuromotorial Sciences, Alma Mater University, 40126 Bologna, Italy.

Mauro Valeri (M)

Center for Animal Experimentation and Well-Being, Istituto Superiore di Sanità, 00161 Rome, Italy.

Giuseppe Sarli (G)

Department of Veterinary Medical Sciences, University of Bologna, 40126 Bologna, Italy.

Christian Marinaccio (C)

Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.

Johanna Melo-Cardenas (J)

Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

John D Crispino (JD)

Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Anna Rita Migliaccio (AR)

Altius Institute for Biomedical Sciences, Seattle, WA 98121, USA.
Center for Integrated Biomedical Research, Campus Bio-Medico, 00128 Rome, Italy.

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Classifications MeSH