Grafting Area Reduction in Peyronie's Disease Surgery: Comparative Assessment Between Double Y Vs iGrafter APP Using 3D-Printed Penile Models.


Journal

The journal of sexual medicine
ISSN: 1743-6109
Titre abrégé: J Sex Med
Pays: Netherlands
ID NLM: 101230693

Informations de publication

Date de publication:
04 2022
Historique:
received: 16 10 2021
revised: 12 12 2021
accepted: 06 01 2022
pubmed: 28 2 2022
medline: 12 4 2022
entrez: 27 2 2022
Statut: ppublish

Résumé

The use of plaque incision and graft techniques (PIG) for the treatment of severe Peyronie's disease (PD), may lead to erectile dysfunction (ED); graft size is 1 of the contributing factors for post-PIG ED. Recently the iGrafter software APP was introduced using a mathematical algorithm to distribute the incisions along the penile length resulting in a smaller grafting area. Compare 2 PIG techniques, the Double-Y(DY) and iGrafter, in 3 main aspects: (i) Total grafting area; (ii) The variation in calculating the grafting to be used; (iii) time to perform the PIG. Six urologists with expertise in sexual medicine performed both techniques twice using four 3-D validated training models for PD with a standard 60° uniplanar dorsal curvature. The graft areas and operative partial and total time for each step of the operation were recorded for each procedure. Unpaired t-test and the coefficient of variation for graft area across surgeons was calculated comparing both techniques. For all surgeons, the use of iGrafter resulted in 2 grafts, for the DY technique in 1 graft. Overall, TT for the iGrafter was significantly longer than for DY technique (49.4 ± 11 vs 40.7 ± 5.7 minute; P = .02), The iGrafter grafting area was significantly smaller (11.6 ± 1.2 vs 23.3 ± 5.4 cm The iGrafter, when compared to DY technique, reduced the graft area by 50%, which potentially means less erectile dysfunction. Our study eliminates anatomical variations found in a real clinical case making it possible to compare surgical techniques with the same penile anatomy. However, the 3D-printed model cannot replicate the living human tissue property preventing a simulation close to actual surgery. The use of the iGrafter software for PIG surgery has shown to be a promising technique for severe PD management resulting in smaller graft size (about 50% smaller when compared to the DY), although it might be more time-consuming. Tourchi A, Nascimento B, de Freita Miranda A, et al. Grafting Area Reduction in Peyronie's Disease Surgery: Comparative Assessment Between Double Y Vs iGrafter APP Using 3D-Printed Penile Models. J Sex Med 2022;19:669-675.

Sections du résumé

BACKGROUND
The use of plaque incision and graft techniques (PIG) for the treatment of severe Peyronie's disease (PD), may lead to erectile dysfunction (ED); graft size is 1 of the contributing factors for post-PIG ED. Recently the iGrafter software APP was introduced using a mathematical algorithm to distribute the incisions along the penile length resulting in a smaller grafting area.
AIM
Compare 2 PIG techniques, the Double-Y(DY) and iGrafter, in 3 main aspects: (i) Total grafting area; (ii) The variation in calculating the grafting to be used; (iii) time to perform the PIG.
METHODS
Six urologists with expertise in sexual medicine performed both techniques twice using four 3-D validated training models for PD with a standard 60° uniplanar dorsal curvature.
OUTCOMES
The graft areas and operative partial and total time for each step of the operation were recorded for each procedure. Unpaired t-test and the coefficient of variation for graft area across surgeons was calculated comparing both techniques.
RESULTS
For all surgeons, the use of iGrafter resulted in 2 grafts, for the DY technique in 1 graft. Overall, TT for the iGrafter was significantly longer than for DY technique (49.4 ± 11 vs 40.7 ± 5.7 minute; P = .02), The iGrafter grafting area was significantly smaller (11.6 ± 1.2 vs 23.3 ± 5.4 cm
CLINICAL SIGNIFICANCE
The iGrafter, when compared to DY technique, reduced the graft area by 50%, which potentially means less erectile dysfunction.
STRENGTHS AND LIMITATIONS
Our study eliminates anatomical variations found in a real clinical case making it possible to compare surgical techniques with the same penile anatomy. However, the 3D-printed model cannot replicate the living human tissue property preventing a simulation close to actual surgery.
CONCLUSION
The use of the iGrafter software for PIG surgery has shown to be a promising technique for severe PD management resulting in smaller graft size (about 50% smaller when compared to the DY), although it might be more time-consuming. Tourchi A, Nascimento B, de Freita Miranda A, et al. Grafting Area Reduction in Peyronie's Disease Surgery: Comparative Assessment Between Double Y Vs iGrafter APP Using 3D-Printed Penile Models. J Sex Med 2022;19:669-675.

Identifiants

pubmed: 35219638
pii: S1743-6095(22)00037-6
doi: 10.1016/j.jsxm.2022.01.010
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

669-675

Informations de copyright

Copyright © 2022 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.

Auteurs

Ali Tourchi (A)

Department of Urology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Bruno Nascimento (B)

Department of Urology, Universidade de São Paulo, São Paulo, São Paulo, Brazil.

Alexandre de Freitas Miranda (A)

Department of Urology, Hospital Federal de Ipanema, Rio de Janeiro, RJ, Brazil.

Eduardo Miranda (E)

Department of Surgery, Urology Division, Universidade Federal do Ceará, Fortaleza, Ceará, Brazil.

José Bessa (J)

Department of Urology, Universidade de São Paulo, São Paulo, São Paulo, Brazil.

William C Nahas (WC)

Department of Urology, Universidade de São Paulo, São Paulo, São Paulo, Brazil.

Rogério Sayão Filho (RS)

Department of Urology, Universidade de São Paulo, São Paulo, São Paulo, Brazil.

Miguel Srougi (M)

Department of Urology, Universidade de São Paulo, São Paulo, São Paulo, Brazil.

Bruno Machado (B)

Department of Urology, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address: bmachado@uams.edu.

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