Association between preoperative diastolic dysfunction and early allograft dysfunction after orthotopic liver transplantation: An observational study.


Journal

Echocardiography (Mount Kisco, N.Y.)
ISSN: 1540-8175
Titre abrégé: Echocardiography
Pays: United States
ID NLM: 8511187

Informations de publication

Date de publication:
04 2022
Historique:
revised: 30 01 2022
received: 30 09 2021
accepted: 16 02 2022
pubmed: 1 3 2022
medline: 13 4 2022
entrez: 28 2 2022
Statut: ppublish

Résumé

To investigate the association between the grade of diastolic dysfunction (DD) and the occurrence of early allograft dysfunction (EAD) in liver transplant patients following the new 2016 American Society of Echocardiography/European Association of Cardiovascular Imaging (ASE/EACVI) guidelines. From January 2015 to December 2019, we retrospectively analyzed 83 patients who underwent orthotopic liver transplantation (OLTx) and their susceptibility to develop EAD according to the grade of preoperative DD. EAD was defined according to the criteria proposed by Olfhoff et al.; DD was defined with four parameters: E/A, e/e', Left Atrium volume, and Tricuspid Regurgitation velocity. According to the ASE/EACVI guidelines grade II DD was detected in 20 patients (24.1%) undergoing OLTx. A statistically significant association was found between grade II DD and the occurrence of EAD (p-value < 0.003). The Kaplan-Meier analysis failed to find any significant difference between the survival probability, nevertheless at the end of a 90-day follow-up period, mortality showed a different trend in classes with more severe diastolic dysfunction. According to the ASE/EACVI guidelines from 2016, patients with grade II DD seem to have a higher propensity to develop early allograft dysfunction EAD after OLTx. Our study advises a need for an urgent prospective multicenter study to elucidate the long-term outcomes of liver transplants patients with diastolic dysfunction.

Identifiants

pubmed: 35224775
doi: 10.1111/echo.15328
doi:

Types de publication

Journal Article Multicenter Study Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

561-567

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2022 Wiley Periodicals LLC.

Références

Smilowitz NR, Gupta N, Ramakrishna H, Guo Y, Berger JS, Bangalore S. Perioperative major adverse cardiovascular and cerebrovascular events associated with noncardiac surgery. JAMA Cardiol. 2017;2:181-187.
Wijeysundera DN, Beattie WS, Karkouti K, Neuman MD, Austin PC, Laupacis A. Association of echocardiography before major elective non-cardiac surgery with postoperative survival and length of hospital stay: population based cohort study. BMJ. 2011;342:d3695.
Lerman BJ, Popat RA, Assimes TL, Heidenreich PA, Wren SM. Association of left ventricular ejection fraction and symptoms with mortality after elective noncardiac surgery among patients with heart failure. JAMA. 2019;321(6):572-579.
Cho DH, Park SM, Kim MN, Kim SA, Lim H, Shim WJ. Presence of preoperative diastolic dysfunction predicts postoperative pulmonary edema and cardiovascular complications in patients undergoing noncardiac surgery. Echocardiography. 2014;31(1):42-49.
Willingham M, Ayoubi SA, Doan M, et al. Preoperative diastolic dysfunction and postoperative outcomes after noncardiac surgery. J Cardiothorac Vasc Anesth. 2020;34(3):679-686.
Lavine SJ, Al Balbissi K. Adverse cardiac events and the impaired relaxation left ventricular filling pattern. J Am Soc Echocardiogr. 2016;29(7):699-708.
Nagueh SF, Smiseth OA, Appleton CP, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2016;29(4):277-314.
Nagueh SF, Appleton CP, Gillebert TC, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiogr. 2009;22(2):107-133.
Raevens S, De Pauw M, Geerts A, et al. Prevalence and outcome of diastolic dysfunction in liver transplantation recipients. Acta Cardiol. 2014;69(3):273-280.
Shounak M, Vimal R, Colin S, David IS. A retrospective analysis of the impact of diastolic dysfunction on one-year mortality after transjugular intrahepatic porto-systemic shunt, liver transplantation and non-transplant abdominal surgery in patients with cirrhosis. Ann Gastroenterol. 2015;28(3):385-390.
Olthoff KM, Kulik L, Samstein B, et al. Validation of a current definition of early allograft dysfunction in liver transplant recipients and analysis of risk factors. Liver Transpl. 2010;16(8):943-949.
Møller S, Bernardi M. Interactions of the heart and the liver. Eur Heart J. 2013;34(36):2804-2811.
Kaw R, Hernandez AV, Pasupuleti V, et al. Cardiovascular Meta-analyses Research Group. Effect of diastolic dysfunction on postoperative outcomes after cardiovascular surgery: a systematic review and meta-analysis. J Thorac Cardiovasc Surg. 2016;152(4):1142-1153.
Mazzaferro V, Bhoori S, Sposito C, et al. Milan criteria in liver transplantation for hepatocellular carcinoma: an evidence-based analysis of 15 years of experience. Liver Transpl. 2011;17Suppl2:S44-S57.
Avriel A, Klement AH, Johnson SR, de Perrot M, Granton J. Impact of left ventricular diastolic dysfunction on lung transplantation outcome in patients with pulmonary arterial hypertension. Am J Transplant. 2017;17(10):2705-2711.
Higashi M, Yamaura K, Ikeda M, Shimauchi T, Saiki H, Hoka S. Diastolic dysfunction of the left ventricle is associated with pulmonary edema after renal transplantation. Acta Anaesthesiol Scand. 2013;57(9):1154-1160.
Teshome M, Asfaw AA, Fughhi I, Doukky R. Pre-renal transplant diastolic dysfunction is an independent predictor of post transplant major cardiac events. Circulation. 2017;136:A17383.
Mittal C, Qureshi W, Singla S, Ahmad U, Huang MA. Pre-transplant left ventricular diastolic dysfunction is associated with post transplant acute graft rejection and graft failure. Dig Dis Sci. 2014;59(3):674-680.
Sharma S, Karamchandani K, Wilson R, Baskin S, Bezinover D. Acute heart failure after Orthotopic liver transplantation: a case series from one center. BMC Anesthesiol. 2018;18(1):102.
Fayad A, Ansari MT, Yang H, Ruddy T, Wells GA. Perioperative diastolic dysfunction in patients undergoing noncardiac surgery is an independent risk factor for cardiovascular events: a systematic review and meta-analysis. Anesthesiology. 2016;125(1):72-91.
Toda H, Nakamura K, Nakagawa K, et al. Diastolic Dysfunction Is a Risk of Perioperative Myocardial Injury Assessed by High-Sensitivity Cardiac Troponin T in Elderly Patients Undergoing Non-Cardiac Surgery. Circ J. 2018;82(3):775-782.
Yoon J, Salamanca-Padilla Y. Effect of left ventricular diastolic dysfunction on development of primary graft dysfunction after lung transplant. Curr Opin Anaesthesiol. 2020;33(1):10-16.
Carvalheiro F, Rodrigues C, Adrego T, et al. Diastolic dysfunction in liver cirrhosis: prognostic predictor in liver transplantation?. Transplant Proc. 2016;48(1):128-131.
Park J, Lee J, Kwon A, et al. The 2016 ASE/EACVI recommendations may be able to more accurately identify patients at risk for diastolic dysfunction in living donor liver transplantation. PLoS One. 2019;14(4):e0215603.
Thomas L, Marwick TH, Popescu BA, Donal E, Badano LP. Left atrial structure and function, and left ventricular diastolic dysfunction: JACC state-of-the-art review. J Am Coll Cardiol. 2019;73(15):1961-1977.
Vetrugno L, Barnariol F, Bignami E, et al. Transesophageal ultrasonography during orthotopic liver transplantation: show me more. Echocardiography. 2018;35(8):1204-1215.
Bellini V, Sanfilippo F, Vetrugno L, Bignami E. Artificial intelligence and left ventricular diastolic function assessment: a new tool for improved practice?. J Cardiothorac Vasc Anesth. 2021;35(9):2834.

Auteurs

Luigi Vetrugno (L)

Department of Medical, Oral, and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy.

Vittorio Cherchi (V)

General Surgery Clinic and Liver Transplant Center, University-Hospital of Udine, Udine, Italy.

Victor Zanini (V)

Department of Medicine, University of Udine, Udine, Italy.

Silvia Cotrozzi (S)

Department of Medicine, University of Udine, Udine, Italy.

Marco Ventin (M)

Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.

Giovanni Terrosu (G)

General Surgery Clinic and Liver Transplant Center, University-Hospital of Udine, Udine, Italy.

Umberto Baccarani (U)

General Surgery Clinic and Liver Transplant Center, University-Hospital of Udine, Udine, Italy.

Tiziana Bove (T)

Department of Medicine, University of Udine, Udine, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH