Biological Investigation of a Water-Soluble Isoginkgetin-Phosphate Analogue, Targeting the Spliceosome with

Biflavonoids / pharmacology Phosphates Spliceosomes Water

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
24 03 2022
Historique:
pubmed: 3 3 2022
medline: 7 5 2022
entrez: 2 3 2022
Statut: ppublish

Résumé

The first total synthesis of the natural product Isoginkgetin as well as four water-soluble Isoginkgetin-phosphate analogues is reported herein. Moreover, the full study of the

Identifiants

DOI: 10.1021/acs.jmedchem.1c01654 PMID: 35235336
pubmed: 35235336
doi: 10.1021/acs.jmedchem.1c01654
doi:

Substances chimiques

Biflavonoids 0
Phosphates 0
isoginkgetin 0
Water 059QF0KO0R

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4633-4648

Auteurs

Boris Letribot (B)

Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry 92290, France.

Megane Nascimento (M)

Université Paris-Saclay, Institut Gustave Roussy, Inserm, Immunologie des tumeurs et Immunothérapie, Villejuif 94805, France.

Giulia Cerrato (G)

Université Paris-Saclay, Institut Gustave Roussy, Metabolomics and Cell Biology Platforms, Villejuif 94805, France.

Romain Darrigrand (R)

Université Paris-Saclay, Institut Gustave Roussy, Inserm, Immunologie des tumeurs et Immunothérapie, Villejuif 94805, France.

Valerie Salgues (V)

Université Paris-Saclay, Institut Gustave Roussy, Inserm, Immunologie des tumeurs et Immunothérapie, Villejuif 94805, France.

Dolor Renko (D)

Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry 92290, France.

Alain Pruvost (A)

Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour La Santé, SPI, Gif-sur-Yvette 91191, France.

Mouad Alami (M)

Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry 92290, France.

Samir Messaoudi (S)

Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry 92290, France.
ORCID: 0000-0002-4994-9001

Sebastien Apcher (S)

Université Paris-Saclay, Institut Gustave Roussy, Inserm, Immunologie des tumeurs et Immunothérapie, Villejuif 94805, France.

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › Biflavonoïdes › Biological Investigation of a Water-Soluble...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du phosphore › Acides du phosphore › Acides phosphoriques › Phosphates › Biological Investigation of a Water-Soluble...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Structures nucléaires › Espace intranucléaire › Splicéosomes › Biological Investigation of a Water-Soluble...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Eau › Biological Investigation of a Water-Soluble...