The New York experience of open arch surgery.


Journal

The Journal of cardiovascular surgery
ISSN: 1827-191X
Titre abrégé: J Cardiovasc Surg (Torino)
Pays: Italy
ID NLM: 0066127

Informations de publication

Date de publication:
Jun 2022
Historique:
pubmed: 4 3 2022
medline: 9 6 2022
entrez: 3 3 2022
Statut: ppublish

Résumé

Aortic arch repair has undergone constant evolution since its inception with improving outcomes. A sizeable number of competing techniques and strategies have been described, with no single optimal method endorsed by the surgical community. We describe our experience with open aortic arch repair in a high-volume center. We queried our aortic database for consecutive patients undergoing aortic arch repair from 1997-2021. Those undergoing hemiarch repair were compared to those undergoing total arch repair. Outcomes were compared using multivariate analysis. Of 1308 patients undergoing aortic arch repair, 953 underwent hemiarch repair and 355 underwent total arch repair. The median age was 69 (interquartile ratio 58-76) and 61.7% were men. Hemiarch patients more frequently hade aortic dissection (28.5 vs. 11.8%, P<0.001) and urgent or emergent procedure status (45.1 vs. 30.4%, P<0.001). Overall operative mortality was 2.7% and significantly higher in the hemiarch group (3.5 vs. 0.6%, P=0.007). No difference in the incidence of major adverse events (MAE) including myocardial infarction, cerebrovascular accident, new need for dialysis, re-exploration for bleeding, and tracheostomy was found between the two groups. Multivariate analysis found diabetes, urgent or emergent procedure status, preoperative renal dysfunction, New York Heart Association class III/IV symptoms, and connective tissue disease to be independent predictors of MAE. Retrograde cerebral perfusion with deep hypothermic circulatory arrest is safe and effective, with no appreciable difference in neurologic outcomes when comparing hemiarch to total arch strategies. Rates of mortality and MAE compare favorably with strategies utilizing antegrade cerebral perfusion.

Sections du résumé

BACKGROUND BACKGROUND
Aortic arch repair has undergone constant evolution since its inception with improving outcomes. A sizeable number of competing techniques and strategies have been described, with no single optimal method endorsed by the surgical community. We describe our experience with open aortic arch repair in a high-volume center.
METHODS METHODS
We queried our aortic database for consecutive patients undergoing aortic arch repair from 1997-2021. Those undergoing hemiarch repair were compared to those undergoing total arch repair. Outcomes were compared using multivariate analysis.
RESULTS RESULTS
Of 1308 patients undergoing aortic arch repair, 953 underwent hemiarch repair and 355 underwent total arch repair. The median age was 69 (interquartile ratio 58-76) and 61.7% were men. Hemiarch patients more frequently hade aortic dissection (28.5 vs. 11.8%, P<0.001) and urgent or emergent procedure status (45.1 vs. 30.4%, P<0.001). Overall operative mortality was 2.7% and significantly higher in the hemiarch group (3.5 vs. 0.6%, P=0.007). No difference in the incidence of major adverse events (MAE) including myocardial infarction, cerebrovascular accident, new need for dialysis, re-exploration for bleeding, and tracheostomy was found between the two groups. Multivariate analysis found diabetes, urgent or emergent procedure status, preoperative renal dysfunction, New York Heart Association class III/IV symptoms, and connective tissue disease to be independent predictors of MAE.
CONCLUSIONS CONCLUSIONS
Retrograde cerebral perfusion with deep hypothermic circulatory arrest is safe and effective, with no appreciable difference in neurologic outcomes when comparing hemiarch to total arch strategies. Rates of mortality and MAE compare favorably with strategies utilizing antegrade cerebral perfusion.

Identifiants

pubmed: 35238525
pii: S0021-9509.22.12290-1
doi: 10.23736/S0021-9509.22.12290-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

275-280

Auteurs

Erin Iannacone (E)

Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY, USA - eem9006@med.cornell.edu.

Christopher Lau (C)

Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY, USA.

Mohamed Rahouma (M)

Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY, USA.

Leonard Girardi (L)

Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, NY, USA.

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