Eosinophilic granulomatosis with polyangiitis exhibits T cell activation and IgG4 immune response in the tissue; comparison with IgG4-related disease.
autoimmune diseases
granulomatosis with polyangiitis
inflammation
Journal
RMD open
ISSN: 2056-5933
Titre abrégé: RMD Open
Pays: England
ID NLM: 101662038
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
received:
05
11
2021
accepted:
16
02
2022
entrez:
9
3
2022
pubmed:
10
3
2022
medline:
7
4
2022
Statut:
ppublish
Résumé
To study the pathophysiological differences of EGPA and IgG Clinical and pathological findings were compared in patients with EGPA and IgG An elevation of the IgG4 level was found in all EGPA cases, with the accompanying pathological findings of lymphocytic infiltration and fibrosis observed in 30.8% patients, and the elevation of IgG The elevation of serum IgG
Identifiants
pubmed: 35260476
pii: rmdopen-2021-002086
doi: 10.1136/rmdopen-2021-002086
pmc: PMC8906049
pii:
doi:
Substances chimiques
Immunoglobulin G
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: YM has received consulting fees, speaking fees, and/or honoraria from Eli Lilly and has received research grants from Glaxo Smith Kline. SN has received consulting fees, speaking fees, and/or honoraria from Bristol-Myers, Pfizer, GlaxoSmithKline, Sanofi, Astellas, Asahi-kasei, Boehringer Ingelheim and has received research grants from Mitsubishi-Tanabe and Novartis. YT has received consulting fees, speaking fees, and/or honoraria from Abbvie, Daiichi-Sankyo, Chugai, Takeda, Mitsubishi-Tanabe, Bristol-Myers, Astellas, Eisai, Janssen, Pfizer, Asahi-kasei, Eli Lilly, GlaxoSmithKline, UCB, Teijin, MSD and Santen, and also research grants from Mitsubishi-Tanabe, Takeda, Chugai, Astellas, Eisai, Taisho-Toyama, Kyowa-Kirin, Abbvie, and Bristol-Myers.
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