Upstage Rate of Complex Sclerosing Lesions/Radial Scars.


Journal

The American surgeon
ISSN: 1555-9823
Titre abrégé: Am Surg
Pays: United States
ID NLM: 0370522

Informations de publication

Date de publication:
May 2022
Historique:
pubmed: 10 3 2022
medline: 15 4 2022
entrez: 9 3 2022
Statut: ppublish

Résumé

Radial scars (RS) and complex sclerosing lesions (CSL) are breast radiologic findings described as small, stellate lesions causing architectural distortion. This can mimic malignancy. Core needle biopsy (CNB) is often performed. Advances in breast imaging have led to increased detection of RS/CSL. The upstage rate of RS/CSL to in situ or invasive disease is 0-40%. We sought to determine the upstaging rate of RS/CSL to The pathology database of a single center was searched for RS/CSL, from January 2013 to September 2020. We included CNB without malignancy or high-risk lesion (eg, atypical ductal hyperplasia). Patient demographics, indications for biopsy, imaging findings, biopsy procedure, and final pathology were collected. Forty-four patients were included. 52.3% had CNB for architectural distortion on mammography, 18.2% for mass, 11.4% for calcifications, 2.3% for abnormal MRI, and 15.9% for multiple reasons (eg, calcifications and mass). Most had an ultrasound: 43.2% had no abnormality and 34.1% had a mass. All CNB were vacuum assisted, 65.9% with 9-gauge needle, and averaged 10.0 cores. 77.3% were stereotactic biopsies, 13.6% ultrasound, and 6.8% MRI. 59.1% had excision after CNB. 82.1% of patients did not upstage. One patient upstaged to invasive ductal carcinoma (3.6%) and two patients to high-risk lesion (7.1%). There was low upstage rate of RS/CSL on excisional biopsy. Centers could consider close surveillance for RS/CSL on CNB. Longer follow-up in cases of deferred excision is needed to ensure oncologic safety.

Sections du résumé

BACKGROUND BACKGROUND
Radial scars (RS) and complex sclerosing lesions (CSL) are breast radiologic findings described as small, stellate lesions causing architectural distortion. This can mimic malignancy. Core needle biopsy (CNB) is often performed. Advances in breast imaging have led to increased detection of RS/CSL. The upstage rate of RS/CSL to in situ or invasive disease is 0-40%. We sought to determine the upstaging rate of RS/CSL to
METHODS METHODS
The pathology database of a single center was searched for RS/CSL, from January 2013 to September 2020. We included CNB without malignancy or high-risk lesion (eg, atypical ductal hyperplasia). Patient demographics, indications for biopsy, imaging findings, biopsy procedure, and final pathology were collected.
RESULTS RESULTS
Forty-four patients were included. 52.3% had CNB for architectural distortion on mammography, 18.2% for mass, 11.4% for calcifications, 2.3% for abnormal MRI, and 15.9% for multiple reasons (eg, calcifications and mass). Most had an ultrasound: 43.2% had no abnormality and 34.1% had a mass. All CNB were vacuum assisted, 65.9% with 9-gauge needle, and averaged 10.0 cores. 77.3% were stereotactic biopsies, 13.6% ultrasound, and 6.8% MRI. 59.1% had excision after CNB. 82.1% of patients did not upstage. One patient upstaged to invasive ductal carcinoma (3.6%) and two patients to high-risk lesion (7.1%).
DISCUSSION CONCLUSIONS
There was low upstage rate of RS/CSL on excisional biopsy. Centers could consider close surveillance for RS/CSL on CNB. Longer follow-up in cases of deferred excision is needed to ensure oncologic safety.

Identifiants

pubmed: 35262438
doi: 10.1177/00031348211056282
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

964-967

Auteurs

Veronica M Jones (VM)

Department of Surgery, 12279Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Jane B Pearce (JB)

12279Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Maryam Khalil (M)

12279Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Olivia Cain (O)

1375Spelman College, Atlanta, GA, USA.

Daniel Coldren (D)

Department of Pathology, 12279Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Harrison Martin (H)

Department of Pathology, 12279Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Marissa Howard-McNatt (M)

Department of Surgery, 12279Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Edward Levine (E)

Department of Surgery, 12279Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Akiko Chiba (A)

Department of Surgery, 12279Wake Forest University School of Medicine, Winston-Salem, NC, USA.

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