Peptide-Conjugated Silver Nanoparticles for the Colorimetric Detection of the Oncoprotein Mdm2 in Human Serum.
Journal
ChemPlusChem
ISSN: 2192-6506
Titre abrégé: Chempluschem
Pays: Germany
ID NLM: 101580948
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
pubmed:
11
3
2022
medline:
6
4
2022
entrez:
10
3
2022
Statut:
ppublish
Résumé
Invited for this month's cover are the collaborating groups of Prof. Gilles Bruylants and Prof. Ivan Jabin, Université libre de Bruxelles, Belgium. The cover picture shows the principle of a colorimetric sensor, based on peptide-conjugated silver nanoparticles, for the detection of the cancer biomarker Mdm2. The particles were functionalized via a recently developed strategy based on the use of calixarene diazonium salts. The calixarene-based coating provides an unprecedented stability to the silver nanoparticles, enabling their use as colorimetric reporters for in vitro diagnostics. The cover was designed by I. Jabin. More information can be found in the Research Article by I. Jabin, G. Bruylants, and co-workers.
Identifiants
pubmed: 35266324
doi: 10.1002/cplu.202200043
doi:
Substances chimiques
Oncogene Proteins
0
Peptides
0
Silver
3M4G523W1G
MDM2 protein, human
EC 2.3.2.27
Proto-Oncogene Proteins c-mdm2
EC 2.3.2.27
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202200043Informations de copyright
© 2022 Wiley-VCH GmbH.