Reorienting Mechanism of Harderoheme in Coproheme Decarboxylase-A Computational Study.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
25 Feb 2022
Historique:
received: 27 01 2022
revised: 16 02 2022
accepted: 23 02 2022
entrez: 10 3 2022
pubmed: 11 3 2022
medline: 9 4 2022
Statut: epublish

Résumé

Coproheme decarboxylase (ChdC) is an important enzyme in the coproporphyrin-dependent pathway (CPD) of Gram-positive bacteria that decarboxylates coproheme on two propionates at position 2 and position 4 sequentially to generate heme b by using H

Identifiants

pubmed: 35269706
pii: ijms23052564
doi: 10.3390/ijms23052564
pmc: PMC8910490
pii:
doi:

Substances chimiques

Propionates 0
Heme 42VZT0U6YR
Hydrogen Peroxide BBX060AN9V
Carboxy-Lyases EC 4.1.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Natural Science Foundation of China
ID : 22073010

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Auteurs

Wei Liu (W)

Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.

Yunjie Pang (Y)

Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.

Yutian Song (Y)

Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.

Xichen Li (X)

Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.

Hongwei Tan (H)

Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.

Guangju Chen (G)

Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.

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Classifications MeSH