Feasibility and Acceptability of a Dietary Intervention to Reduce Salt Intake and Increase High-Nitrate Vegetable Consumption in Malaysian Middle-Aged and Older Adults with Elevated Blood Pressure: Findings from the DePEC-Nutrition Trial.

dementia dietary nitrate feasibility trial randomised controlled trial reduced salt

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
19 Jan 2022
Historique:
received: 30 10 2021
revised: 08 01 2022
accepted: 10 01 2022
entrez: 12 3 2022
pubmed: 13 3 2022
medline: 16 3 2022
Statut: epublish

Résumé

The DePEC-Nutrition trial is a complex dietary and behavioural intervention of salt intake reduction combined with increased high-nitrate vegetable consumption among Malaysian middle-aged and older adults with elevated blood pressure. This study aimed to assess the feasibility and acceptability of the trial. Participants were recruited from the South East Asia Community Observatory (SEACO) database and randomised into one of four groups: (1) low salt; (2) high-nitrate vegetable; (3) combined high-nitrate vegetable and low salt; and (4) control. The intervention included a combination of group counselling sessions, information booklets, reinforcement videos and text messages to modify dietary behaviour. The primary outcomes evaluated were the measures of feasibility and acceptability of (1) recruitment, follow-up attendance and retention; (2) data collection procedures and clinical outcome measures; and (3) individual and combined multi-modal dietary interventions. A total of 74 participants were recruited, and the 10-month retention rate was 73%. Data collection procedures were acceptable with minimal missing data. All intervention strategies were feasible and acceptable, with group counselling being the most acceptable strategy. This study provides important insights into improving the screening process of participants, facilitating their access to the research facilities and refining the measurement protocols and dietary recommendations, which are instrumental in formulating the design of a full-scale definitive DePEC-Nutrition trial.

Identifiants

pubmed: 35276789
pii: nu14030430
doi: 10.3390/nu14030430
pmc: PMC8839221
pii:
doi:

Substances chimiques

Nitrates 0
Sodium Chloride, Dietary 0

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Institute for Health Research
ID : GHR Group: 16/137/62 NIHR Global Health Research Group on Dementia Prevention and En-hanced Care (DePEC)

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Auteurs

Siew Siew Lee (SS)

Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.

Andrea McGrattan (A)

School of Biomedical, Nutritional and Sports Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.

Yee Chang Soh (YC)

Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.
South East Asia Community Observatory (SEACO), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 45700, Malaysia.

Mawada Alawad (M)

Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.
South East Asia Community Observatory (SEACO), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 45700, Malaysia.

Tin Tin Su (TT)

Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.
South East Asia Community Observatory (SEACO), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 45700, Malaysia.

Uma Devi Palanisamy (UD)

Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.

Azizah Mat Hussin (AM)

Institute of Medical Science Technology, Universiti Kuala Lumpur, Kajang 43000, Malaysia.

Zaid Bin Kassim (ZB)

District Health Office, Pejabat Kesihatan Daerah (PKD) Segamat, Segamat 85000, Malaysia.

Ahmad Nizal Bin Mohd Ghazali (ANB)

District Health Office, Pejabat Kesihatan Daerah (PKD) Segamat, Segamat 85000, Malaysia.

Blossom Christa Maree Stephan (B)

Institute of Mental Health, School of Medicine, University of Nottingham, Nottingham NG7 2TU, UK.

Pascale Allotey (P)

International Institute for Global Health, United Nations University, Kuala Lumpur 56000, Malaysia.

Daniel D Reidpath (DD)

South East Asia Community Observatory (SEACO), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 45700, Malaysia.
International Centre for Diarrhoeal Disease Research, ICDDR, B, Dhaka 1212, Bangladesh.

Louise Robinson (L)

Population Health Science Institute, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.

Devi Mohan (D)

Global Public Health, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway 47500, Malaysia.

Mario Siervo (M)

School of Life Sciences, University of Nottingham Medical School, Nottingham NG7 2UH, UK.

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