The Effect of Dietary Polyphenols on Vascular Health and Hypertension: Current Evidence and Mechanisms of Action.
blood pressure
endothelial
flavonoids
hypertension
phenolic acids
polyphenols
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
27 Jan 2022
27 Jan 2022
Historique:
received:
29
12
2021
revised:
20
01
2022
accepted:
23
01
2022
entrez:
12
3
2022
pubmed:
13
3
2022
medline:
16
3
2022
Statut:
epublish
Résumé
The aim of this review was to explore existing evidence from studies conducted on humans and summarize the mechanisms of action of dietary polyphenols on vascular health, blood pressure and hypertension. There is evidence that some polyphenol-rich foods, including berry fruits rich in anthocyanins, cocoa and green tea rich in flavan-3-ols, almonds and pistachios rich in hydroxycinnamic acids, and soy products rich in isoflavones, are able to improve blood pressure levels. A variety of mechanisms can elucidate the observed effects. Some limitations of the evidence, including variability of polyphenol content in plant-derived foods and human absorption, difficulty disentangling the effects of polyphenols from other dietary compounds, and discrepancy of doses between animal and human studies should be taken into account. While no single food counteracts hypertension, adopting a plant-based dietary pattern including a variety of polyphenol-rich foods is an advisable practice to improve blood pressure.
Identifiants
pubmed: 35276904
pii: nu14030545
doi: 10.3390/nu14030545
pmc: PMC8840535
pii:
doi:
Substances chimiques
Anthocyanins
0
Polyphenols
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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