Costs associated with postoperative intra-abdominal abscess in pediatric perforated appendicitis: A retrospective cohort study.


Journal

Surgery
ISSN: 1532-7361
Titre abrégé: Surgery
Pays: United States
ID NLM: 0417347

Informations de publication

Date de publication:
07 2022
Historique:
received: 20 08 2021
revised: 18 12 2021
accepted: 28 01 2022
pubmed: 14 3 2022
medline: 22 6 2022
entrez: 13 3 2022
Statut: ppublish

Résumé

Intra-abdominal abscess, the most common complication after perforated appendicitis, is associated with considerable economic burden. However, costs of intra-abdominal abscesses in children are unknown. We aimed to evaluate resource utilization and costs attributable to intra-abdominal abscess in pediatric perforated appendicitis. A single-center retrospective analysis was performed of children (<18 years) who underwent appendectomy for perforated appendicitis (2013-2019). Hospital costs incurred during the index admission and within 30 postoperative days were obtained from the hospital accounting system and inflated to 2019 USD. Generalized linear models were used to determine excess resource utilization and costs attributable to intra-abdominal abscess after adjusting for confounders. Of 763 patients, 153 (20%) developed intra-abdominal abscesses. Eighty-one patients with intra-abdominal abscesses (53%) underwent percutaneous abscess drainage. Intra-abdominal abscess was independently associated with a nearly 8-fold increased risk of 30-day readmission (adjusted risk ratio, 7.8 [95% confidence interval, 4.7-13.0]). Patients who developed an intra-abdominal abscess required 6.1 excess hospital bed days compared to patients without intra-abdominal abscess (95% confidence interval, 5.3-7.0). Adjusted mean hospital costs for patients with intra-abdominal abscess totaled $27,394 (95% confidence interval, $25,688-$29,101) versus $15,586 (95% confidence interval, $15,102-$16,069) for patients without intra-abdominal abscess. Intra-abdominal abscess was associated with an incremental cost of $11,809 (95% confidence interval, $10,029-$13,588). Hospital room costs accounted for 66% of excess costs. Postoperative intra-abdominal abscess nearly doubled pediatric perforated appendicitis costs, primarily due to more hospital bed days and associated room costs. Intra-abdominal abscesses resulted in estimated excess costs of $1.8 million during the study period. Even small reductions in intra-abdominal abscess rates or hospital bed days could yield substantial health care savings.

Sections du résumé

BACKGROUND
Intra-abdominal abscess, the most common complication after perforated appendicitis, is associated with considerable economic burden. However, costs of intra-abdominal abscesses in children are unknown. We aimed to evaluate resource utilization and costs attributable to intra-abdominal abscess in pediatric perforated appendicitis.
METHODS
A single-center retrospective analysis was performed of children (<18 years) who underwent appendectomy for perforated appendicitis (2013-2019). Hospital costs incurred during the index admission and within 30 postoperative days were obtained from the hospital accounting system and inflated to 2019 USD. Generalized linear models were used to determine excess resource utilization and costs attributable to intra-abdominal abscess after adjusting for confounders.
RESULTS
Of 763 patients, 153 (20%) developed intra-abdominal abscesses. Eighty-one patients with intra-abdominal abscesses (53%) underwent percutaneous abscess drainage. Intra-abdominal abscess was independently associated with a nearly 8-fold increased risk of 30-day readmission (adjusted risk ratio, 7.8 [95% confidence interval, 4.7-13.0]). Patients who developed an intra-abdominal abscess required 6.1 excess hospital bed days compared to patients without intra-abdominal abscess (95% confidence interval, 5.3-7.0). Adjusted mean hospital costs for patients with intra-abdominal abscess totaled $27,394 (95% confidence interval, $25,688-$29,101) versus $15,586 (95% confidence interval, $15,102-$16,069) for patients without intra-abdominal abscess. Intra-abdominal abscess was associated with an incremental cost of $11,809 (95% confidence interval, $10,029-$13,588). Hospital room costs accounted for 66% of excess costs.
CONCLUSION
Postoperative intra-abdominal abscess nearly doubled pediatric perforated appendicitis costs, primarily due to more hospital bed days and associated room costs. Intra-abdominal abscesses resulted in estimated excess costs of $1.8 million during the study period. Even small reductions in intra-abdominal abscess rates or hospital bed days could yield substantial health care savings.

Identifiants

pubmed: 35279294
pii: S0039-6060(22)00074-5
doi: 10.1016/j.surg.2022.01.042
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

212-218

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Dalya M Ferguson (DM)

Department of Pediatric Surgery, John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Center for Surgical Trials and Evidence-Based Practice (C-STEP), John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Children's Memorial Hermann Hospital, Houston, TX.

Seyed A Arshad (SA)

Department of Pediatric Surgery, John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Center for Surgical Trials and Evidence-Based Practice (C-STEP), John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Children's Memorial Hermann Hospital, Houston, TX.

Elenir B C Avritscher (EBC)

Center for Clinical Research and Evidence-Based Medicine, John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX.

Linda T Li (LT)

Department of Pediatric Surgery, John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Center for Surgical Trials and Evidence-Based Practice (C-STEP), John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Children's Memorial Hermann Hospital, Houston, TX.

Mary T Austin (MT)

Department of Pediatric Surgery, John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Center for Surgical Trials and Evidence-Based Practice (C-STEP), John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Children's Memorial Hermann Hospital, Houston, TX.

Akemi L Kawaguchi (AL)

Department of Pediatric Surgery, John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Center for Surgical Trials and Evidence-Based Practice (C-STEP), John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Children's Memorial Hermann Hospital, Houston, TX.

Kevin P Lally (KP)

Department of Pediatric Surgery, John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Center for Surgical Trials and Evidence-Based Practice (C-STEP), John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Children's Memorial Hermann Hospital, Houston, TX.

KuoJen Tsao (K)

Department of Pediatric Surgery, John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Center for Surgical Trials and Evidence-Based Practice (C-STEP), John P. and Katherine G. McGovern Medical School at UTHealth, Houston, TX; Children's Memorial Hermann Hospital, Houston, TX. Electronic address: kuojen.tsao@uth.tmc.edu.

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