Oxytocin receptors influence the development and maintenance of social behavior in zebrafish (Danio rerio).
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
12 03 2022
12 03 2022
Historique:
received:
21
06
2021
accepted:
21
02
2022
entrez:
13
3
2022
pubmed:
14
3
2022
medline:
29
4
2022
Statut:
epublish
Résumé
Zebrafish are highly social teleost fish and an excellent model to study social behavior. The neuropeptide Oxytocin is associated different social behaviors as well as disorders resulting in social impairment like autism spectrum disorder. However, how Oxytocin receptor signaling affects the development and expression kinetics of social behavior is not known. In this study we investigated the role of the two oxytocin receptors, Oxtr and Oxtrl, in the development and maintenance of social preference and shoaling behavior in 2- to 8-week-old zebrafish. Using CRISPR/Cas9 mediated oxtr and oxtrl knock-out fish, we found that the development of social preference is accelerated if one of the Oxytocin receptors is knocked-out and that the knock-out fish reach significantly higher levels of social preference. Moreover, oxtr
Identifiants
pubmed: 35279678
doi: 10.1038/s41598-022-07990-y
pii: 10.1038/s41598-022-07990-y
pmc: PMC8918347
doi:
Substances chimiques
Receptors, Oxytocin
0
Oxytocin
50-56-6
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4322Informations de copyright
© 2022. The Author(s).
Références
Psychophysiology. 2014 Nov;51(11):1169-77
pubmed: 25082371
Science. 2009 Aug 14;325(5942):862-6
pubmed: 19679811
ACS Chem Biol. 2010 Feb 19;5(2):159-61
pubmed: 20166761
Dev Cogn Neurosci. 2021 Apr;48:100950
pubmed: 33831822
Stress. 2012 Mar;15(2):149-61
pubmed: 21854168
Behav Brain Res. 1996 Feb;75(1-2):27-32
pubmed: 8800657
Behav Brain Res. 2016 Sep 15;311:368-374
pubmed: 27247142
Development. 2006 Feb;133(3):395-406
pubmed: 16396911
Endocrinology. 1997 Jul;138(7):2829-34
pubmed: 9202224
Nat Biotechnol. 2013 Mar;31(3):227-9
pubmed: 23360964
Curr Biol. 2015 Mar 30;25(7):831-46
pubmed: 25754638
Prog Brain Res. 2008;170:79-90
pubmed: 18655874
Horm Behav. 2003 Sep;44(3):178-84
pubmed: 14609540
Elife. 2020 Sep 09;9:
pubmed: 32902385
Mol Psychiatry. 2008 Oct;13(10):980-8
pubmed: 17893705
Brain Res. 1979 Oct 19;175(2):303-14
pubmed: 487159
Science. 1976 Nov 26;194(4268):963-5
pubmed: 982056
Elife. 2021 Feb 26;10:
pubmed: 33634789
J Neurosci. 2021 Oct 20;41(42):8742-8760
pubmed: 34470805
Psychoneuroendocrinology. 2009 Nov;34(10):1542-53
pubmed: 19553027
Dev Psychobiol. 2012 Jan;54(1):28-35
pubmed: 21656763
Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16096-101
pubmed: 16249339
Neurochem Res. 2018 Jun;43(6):1191-1199
pubmed: 29740748
Zebrafish. 2017 Oct;14(5):438-443
pubmed: 28829283
Physiol Behav. 1996 Nov;60(5):1209-15
pubmed: 8916173
Front Neural Circuits. 2015 Aug 18;9:39
pubmed: 26347614
Behav Brain Res. 2011 Jan 20;216(2):647-51
pubmed: 20849881
Sci Rep. 2020 Mar 25;10(1):5435
pubmed: 32214126
Psychopharmacology (Berl). 2006 Apr;185(2):218-25
pubmed: 16418825
Nat Neurosci. 2019 Sep;22(9):1477-1492
pubmed: 31358991
Behav Brain Res. 2017 Jun 15;328:28-38
pubmed: 28377259
Behav Brain Res. 2008 Aug 5;191(1):77-87
pubmed: 18423643
PLoS One. 2017 Jan 5;12(1):e0169705
pubmed: 28056078
Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 1;35(6):1409-15
pubmed: 20837077
Bull Exp Biol Med. 2016 Mar;160(5):605-9
pubmed: 27021111
Mol Neurobiol. 2017 Aug;54(6):4813-4819
pubmed: 27525673
Gene Expr Patterns. 2003 Mar;3(1):105-8
pubmed: 12609611
Behav Brain Res. 2007 Dec 3;184(2):157-66
pubmed: 17707522
Cell Rep. 2017 Nov 7;21(6):1681-1691
pubmed: 29117570
Elife. 2020 Aug 25;9:
pubmed: 32838839
Neuron. 1999 Jun;23(2):325-35
pubmed: 10399938
J Neurosci. 2005 Dec 7;25(49):11489-93
pubmed: 16339042
J Neurosci. 2016 Feb 24;36(8):2517-35
pubmed: 26911697
Behav Ecol Sociobiol. 2015;69:219-226
pubmed: 25620833
Dev Psychobiol. 2018 Jan;60(1):43-56
pubmed: 29091281
Neuroscience. 2010 Apr 14;166(4):1036-42
pubmed: 20096332
PLoS One. 2018 Oct 18;13(10):e0204994
pubmed: 30335773
Biull Eksp Biol Med. 1996 Nov;122(11):487-9
pubmed: 8998332
Nature. 2020 Dec;588(7839):653-657
pubmed: 33268890
Zebrafish. 2008 Dec;5(4):335-9
pubmed: 19133832
Elife. 2017 Jan 17;6:
pubmed: 28094761
Elife. 2020 May 05;9:
pubmed: 32366356
Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 1;35(6):1432-51
pubmed: 20971150
Neuroscience. 2000;95(2):567-75
pubmed: 10658637
Biol Psychiatry. 2011 May 1;69(9):875-82
pubmed: 21306704
J Neurosci. 2001 Oct 15;21(20):8278-85
pubmed: 11588199
Neuron. 2016 May 4;90(3):609-21
pubmed: 27112498
Curr Biol. 2020 Oct 19;30(20):4009-4021.e4
pubmed: 32888479
Anim Behav. 2007 Nov;74(5):1269-1275
pubmed: 18978932
J Mol Evol. 2004 Aug;59(2):190-203
pubmed: 15486693
Development. 1996 Jan;122(1):271-80
pubmed: 8565839
J Psychosom Obstet Gynaecol. 1998 Mar;19(1):49-58
pubmed: 9575469
J Neurosci. 2013 Sep 25;33(39):15382-7
pubmed: 24068805
iScience. 2020 Mar 27;23(3):100942
pubmed: 32179471
J Pharmacol Exp Ther. 1977 Oct;203(1):120-4
pubmed: 909047
J Neurosci Methods. 2014 Aug 30;234:66-72
pubmed: 24970579
Horm Behav. 2019 May;111:60-69
pubmed: 30713102
Peptides. 2013 May;43:20-6
pubmed: 23439320
Zoology (Jena). 2021 Apr;145:125896
pubmed: 33581423
Acta Physiol Scand. 1992 Apr;144(4):487-8
pubmed: 1605050
Biol Psychiatry. 2010 Apr 1;67(7):692-4
pubmed: 19897177
J Autism Dev Disord. 1982 Sep;12(3):303-8
pubmed: 7153204
J Neuroendocrinol. 2013 Feb;25(2):107-18
pubmed: 22967062
J Physiol. 2020 Sep;598(18):3793-3801
pubmed: 32666574
Endocrinology. 2003 Jun;144(6):2291-6
pubmed: 12746288
Neuropharmacology. 2019 Sep 15;156:107504
pubmed: 30664846
J Neurodev Disord. 2011 Jun;3(2):101-12
pubmed: 21484202
J Pharmacol Pharmacother. 2013 Oct;4(4):303-6
pubmed: 24250214
J Neurosci Methods. 2014 Aug 30;234:59-65
pubmed: 24793400
J Neuroendocrinol. 2020 Apr;32(4):e12834
pubmed: 31961994
Zebrafish. 2011 Jun;8(2):73-81
pubmed: 21612540
Behav Brain Res. 2008 Mar 17;188(1):168-77
pubmed: 18054804
Am J Obstet Gynecol. 1954 May;67(5):1028-34
pubmed: 13148259