Lymphatics in Cardiovascular Physiology.

Biomarkers Cardiovascular Diseases Cardiovascular Physiological Phenomena Heart Failure Humans Lymphatic Vessels / pathology

Journal

Cold Spring Harbor perspectives in medicine
ISSN: 2157-1422
Titre abrégé: Cold Spring Harb Perspect Med
Pays: United States
ID NLM: 101571139

Informations de publication

Date de publication:
15 08 2022
Historique:
pubmed: 16 3 2022
medline: 18 8 2022
entrez: 15 3 2022
Statut: epublish

Résumé

The lymphatic vessels play an essential role in maintaining immune and fluid homeostasis and in the transport of dietary lipids. The discovery of lymphatic endothelial cell-specific markers facilitated the visualization and mechanistic analysis of lymphatic vessels over the past two decades. As a result, lymphatic vessels have emerged as a crucial player in the pathogenesis of several cardiovascular diseases, as demonstrated by worsened disease progression caused by perturbations to lymphatic function. In this review, we discuss the major findings on the role of lymphatic vessels in cardiovascular diseases such as hypertension, obesity, atherosclerosis, myocardial infarction, and heart failure.

Identifiants

DOI: 10.1101/cshperspect.a041173 PMID: 35288403 PMC: PMC9378713
pubmed: 35288403
pii: cshperspect.a041173
doi: 10.1101/cshperspect.a041173
pmc: PMC9378713
mid: NIHMS1816272
pii:
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK120493
Pays : United States

Informations de copyright

Copyright © 2022 Cold Spring Harbor Laboratory Press; all rights reserved.

Auteurs

Dakshnapriya Balasubbramanian (D)

Vascular Biology Program, Boston Children's Hospital, Boston, Massachusetts 02115, USA.
Department of Surgery, Harvard Medical School, Boston, Massachusetts 02115, USA.

Brett M Mitchell (BM)

Department of Medical Physiology, Texas A&M University College of Medicine, Bryan, Texas 77807, USA.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Lymphatics in Cardiovascular Physiology.
questionsmedicales.fr › Maladies cardiovasculaires › Lymphatics in Cardiovascular Physiology.
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Lymphatics in Cardiovascular Physiology.
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Défaillance cardiaque › Lymphatics in Cardiovascular Physiology.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Lymphatics in Cardiovascular Physiology.
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Vaisseaux lymphatiques › Lymphatics in Cardiovascular Physiology.