Population genetics in microchannels.
bacterial evolution
individual-based models
microfluidics
spatial population dynamics
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
22 03 2022
22 03 2022
Historique:
entrez:
18
3
2022
pubmed:
19
3
2022
medline:
28
4
2022
Statut:
ppublish
Résumé
SignificanceMany microbial populations proliferate in small channels. In such environments, reproducing cells organize in parallel lanes. Reproducing cells shift these lanes, potentially expelling other cells from the channel. In this paper, we combine theory and experiments to understand how these dynamics affects the diversity of a microbial population. We theoretically predict that genetic diversity is quickly lost along lanes of cells. Our experiments confirm that a population of proliferating
Identifiants
pubmed: 35302890
doi: 10.1073/pnas.2120821119
pmc: PMC8944277
doi:
Substances chimiques
Soil
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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