Pressurized Natural Deep Eutectic Solvent Extraction of Galanthamine and Related Alkaloids from Narcissus pseudonarcissus.


Journal

Planta medica
ISSN: 1439-0221
Titre abrégé: Planta Med
Pays: Germany
ID NLM: 0066751

Informations de publication

Date de publication:
08 2022
Historique:
pubmed: 20 3 2022
medline: 4 8 2022
entrez: 19 3 2022
Statut: ppublish

Résumé

The isolation of a compound from a natural source involves many organic and mostly toxic solvents for extraction and purification. Natural deep eutectic solvents have been shown to be efficient options for the extraction of natural products. They have the advantage of being composed of abundantly available common primary metabolites, being nontoxic and environmentally safe solvents. The aim of this study was to develop a natural deep eutectic solvent-based extraction method for galanthamine, an important therapeutic agent for the treatment of Alzheimer's disease. This alkaloid can be produced by synthesis or by extraction from

Identifiants

pubmed: 35304734
doi: 10.1055/a-1803-3259
doi:

Substances chimiques

Alkaloids 0
Deep Eutectic Solvents 0
Ionic Liquids 0
Solvents 0
Galantamine 0D3Q044KCA

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

814-825

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare that they have no conflict of interest.

Auteurs

Orchidea Rachmaniah (O)

Institute Technology of Sepuluh Nopember, Chemical Engineering Department, Surabaya, Indonesia.

Erica G Wilson (EG)

Natural Products Laboratory, Institute of Biology Leiden, Leiden University, Leiden, The Netherlands.

Young Hae Choi (YH)

Natural Products Laboratory, Institute of Biology Leiden, Leiden University, Leiden, The Netherlands.
College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.

Geert-Jan Witkamp (GJ)

King Abdullah University of Science and Technology (KAUST), Biology and Environmental Science and Engineering, Thuwal, Saudi Arabia.

Robert Verpoorte (R)

Natural Products Laboratory, Institute of Biology Leiden, Leiden University, Leiden, The Netherlands.

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Classifications MeSH