Recovery and partial isolation of ⍺-mangostin from mangosteen pericarpsvia sequential extraction and precipitation.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2024
Historique:
received: 23 02 2024
accepted: 01 09 2024
medline: 25 10 2024
pubmed: 25 10 2024
entrez: 25 10 2024
Statut: epublish

Résumé

This study introduced an innovative sequential extraction methodology designed for the efficient recovery of alpha-mangostin (⍺-M) from mangosteen pericarps. Alpha-mangostin, renowned for its pharmacological properties including anti-inflammatory, anti-cancer, and anti-bacterial effects, has garnered significant attention across diverse industries. The proposed method of sequential extraction achieved 73% recovery and a yield of 46.75 mg/g based on the weight/weight percentage of the mass of ⍺-M extracted from the sequence and the mass of raw material. Furthermore, the purity of the dried product was 67.9%. The sequence solvent extraction system, comprising water, hexane, and acetonitrile, plays a pivotal role in enhancing the efficacy of the extraction process. Notably, this methodology offers a cost-effective alternative to conventional extraction methods. It reduces the need for complex equipment and processes, positioning it as a resource-efficient extraction technique in comparison to existing methodologies. This novel sequential extraction method presents a promising avenue for the economical and sustainable recovery of alpha-mangostin (⍺-M) from pericarps.

Identifiants

pubmed: 39453921
doi: 10.1371/journal.pone.0310453
pii: PONE-D-24-07293
doi:

Substances chimiques

Xanthones 0
mangostin U6RIV93RU1
Plant Extracts 0
Solvents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0310453

Informations de copyright

Copyright: © 2024 Han et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Auteurs

Moh Moh Han (MM)

Department of Chemical Engineering, Faculty of Engineering, Kasetsart University, Bangkok, Thailand.

Preuk Tangpromphan (P)

Center for High-Value Products from Bioresources, Department of Chemical Engineering, Faculty of Engineering, Kasetsart University, Bangkok, Thailand.

Amaraporn Kaewchada (A)

Department of Agro-Industrial, Food, and Environmental Technology, King Mongkut's University of Technology North Bangkok, Bangkok, Thailand.

Attasak Jaree (A)

Center for High-Value Products from Bioresources, Department of Chemical Engineering, Faculty of Engineering, Kasetsart University, Bangkok, Thailand.

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Classifications MeSH