Work stress and loss of years lived without chronic disease: an 18-year follow-up of 1.5 million employees in Denmark.


Journal

European journal of epidemiology
ISSN: 1573-7284
Titre abrégé: Eur J Epidemiol
Pays: Netherlands
ID NLM: 8508062

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 17 08 2021
accepted: 07 02 2022
pubmed: 22 3 2022
medline: 15 6 2022
entrez: 21 3 2022
Statut: ppublish

Résumé

We aimed to examine the association between exposure to work stress and chronic disease incidence and loss of chronic disease-free life years in the Danish workforce. The study population included 1,592,491 employees, aged 30-59 in 2000 and without prevalent chronic diseases. We assessed work stress as the combination of job strain and effort-reward imbalance using job exposure matrices. We used Cox regressions to estimate risk of incident hospital-diagnoses or death of chronic diseases (i.e., type 2 diabetes, coronary heart disease, stroke, cancer, asthma, chronic obstructive pulmonary disease, heart failure, and dementia) during 18 years of follow-up and calculated corresponding chronic disease-free life expectancy from age 30 to age 75. Individuals working in occupations with high prevalence of work stress had a higher risk of incident chronic disease compared to those in occupations with low prevalence of work stress (women: HR 1.04 (95% CI 1.02-1.05), men: HR 1.12 (95% CI 1.11-1.14)). The corresponding loss in chronic disease-free life expectancy was 0.25 (95% CI - 0.10 to 0.60) and 0.84 (95% CI 0.56-1.11) years in women and men, respectively. Additional adjustment for health behaviours attenuated these associations among men. We conclude that men working in high-stress occupations have a small loss of years lived without chronic disease compared to men working in low-stress occupations. This finding appeared to be partially attributable to harmful health behaviours. In women, high work stress indicated a very small and statistically non-significant loss of years lived without chronic disease.

Identifiants

pubmed: 35312925
doi: 10.1007/s10654-022-00852-x
pii: 10.1007/s10654-022-00852-x
pmc: PMC9187572
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

389-400

Subventions

Organisme : Forskningsrådet om Hälsa, Arbetsliv och Välfärd
ID : 2017-01943
Organisme : Arbejdstilsynet
ID : 27-2017-03
Organisme : Academy of Finland
ID : 329202
Organisme : Arbejdstilsynet
ID : 17-2014-03
Organisme : Nordisk Ministerråd
ID : 75021
Organisme : Medical Research Council
ID : MR/S011676/1
Pays : United Kingdom

Informations de copyright

© 2022. The Author(s).

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Auteurs

Jeppe K Sørensen (JK)

National Research Centre for the Working Environment, Lersø Parkalle 105, 2100, Copenhagen, Denmark. jks@nrcwe.dk.

Elisabeth Framke (E)

National Research Centre for the Working Environment, Lersø Parkalle 105, 2100, Copenhagen, Denmark.
The Danish Multiple Sclerosis Registry, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark.

Jacob Pedersen (J)

National Research Centre for the Working Environment, Lersø Parkalle 105, 2100, Copenhagen, Denmark.

Kristina Alexanderson (K)

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.

Jens P Bonde (JP)

Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23F, 2400, Copenhagen, Frederiksberg, Denmark.
Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.

Kristin Farrants (K)

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.

Esben M Flachs (EM)

Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23F, 2400, Copenhagen, Frederiksberg, Denmark.

Linda L Magnusson Hanson (LL)

Stress Research Institute at Department of Psychology, Stockholm University, Frescati Hagväg 16A, 114 19, Stockholm, Sweden.

Solja T Nyberg (ST)

Department of Public Health, Clinicum, Faculty of Medicine, University of Helsinki, Yliopistonkatu 3, 00014, Helsinki, Finland.

Mika Kivimäki (M)

Department of Public Health, Clinicum, Faculty of Medicine, University of Helsinki, Yliopistonkatu 3, 00014, Helsinki, Finland.
Finnish Institute of Occupational Health, Topeliuksenkatu 41 B, 00250, Helsinki, Finland.
Department of Epidemiology and Public Health, University College of London, 1-19 Torrington Place, London, WC1E 6BT, UK.

Ida E H Madsen (IEH)

National Research Centre for the Working Environment, Lersø Parkalle 105, 2100, Copenhagen, Denmark.

Reiner Rugulies (R)

National Research Centre for the Working Environment, Lersø Parkalle 105, 2100, Copenhagen, Denmark.
Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
Department of Psychology, University of Copenhagen, Øster Farimagsgade 2A, 1353, Copenhagen, Denmark.

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