A

Animals Apolipoproteins E / genetics Diet, Western / adverse effects Liver / metabolism Lupinus / metabolism Mice Proprotein Convertase 9 / genetics Protein Hydrolysates / metabolism Receptors, LDL / genetics

Journal

Food & function
ISSN: 2042-650X
Titre abrégé: Food Funct
Pays: England
ID NLM: 101549033

Informations de publication

Date de publication:
04 Apr 2022
Historique:
pubmed: 23 3 2022
medline: 6 4 2022
entrez: 22 3 2022
Statut: epublish

Résumé

Lupin protein hydrolysates (LPHs) are gaining attention in the food and nutraceutical industries due to their several beneficial health effects. Recently, we have shown that LPH treatment reduces liver cholesterol and triglyceride levels in hypercholesterolemic mice. The aim of this study was to elucidate the effects of LPH treatment on the molecular mechanism underlying liver cholesterol metabolism in ApoE

Identifiants

DOI: 10.1039/d1fo03847h PMID: 35316320
pubmed: 35316320
doi: 10.1039/d1fo03847h
doi:

Substances chimiques

Apolipoproteins E 0
Protein Hydrolysates 0
Receptors, LDL 0
PCSK9 protein, human EC 3.4.21.-
Pcsk9 protein, mouse EC 3.4.21.-
Proprotein Convertase 9 EC 3.4.21.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4158-4170

Auteurs

Guillermo Santos-Sánchez (G)

Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy. carmen.lammi@unimi.it.
Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Universidad de Sevilla, 41009 Seville, Spain. vico@us.es.
Instituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.
ORCID: 0000-0001-5790-2302

Ivan Cruz-Chamorro (I)

Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy. carmen.lammi@unimi.it.
Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Universidad de Sevilla, 41009 Seville, Spain. vico@us.es.
Instituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.
ORCID: 0000-0002-6547-8078

Carlotta Bollati (C)

Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy. carmen.lammi@unimi.it.
ORCID: 0000-0002-5698-1325

Martina Bartolomei (M)

Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy. carmen.lammi@unimi.it.
ORCID: 0000-0002-3851-3392

Justo Pedroche (J)

Department of Food & Health, Instituto de la Grasa, CSIC, Ctra, Utrera Km 1, 41013 Seville, Spain.

Francisco Millán (F)

Department of Food & Health, Instituto de la Grasa, CSIC, Ctra, Utrera Km 1, 41013 Seville, Spain.

María Del Carmen Millán-Linares (MDC)

Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Universidad de Sevilla, 41009 Seville, Spain. vico@us.es.
Department of Food & Health, Instituto de la Grasa, CSIC, Ctra, Utrera Km 1, 41013 Seville, Spain.
ORCID: 0000-0002-5661-8366

Anna Laura Capriotti (AL)

Dipartimento di Chimica, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0003-1017-9625

Andrea Cerrato (A)

Dipartimento di Chimica, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0001-6625-8782

Aldo Laganà (A)

Dipartimento di Chimica, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0003-4963-3020

Anna Arnoldi (A)

Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy. carmen.lammi@unimi.it.

Antonio Carrillo-Vico (A)

Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Universidad de Sevilla, 41009 Seville, Spain. vico@us.es.
Instituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.
ORCID: 0000-0002-8516-0999

Carmen Lammi (C)

Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy. carmen.lammi@unimi.it.
ORCID: 0000-0002-7428-4486

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › A
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Lipoprotéines › Apolipoprotéines › Apolipoprotéines E › A
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Régime alimentaire › Régime occidental › A
questionsmedicales.fr › Système digestif › Foie › A
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Fabaceae › Lupinus › A
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Protéases à sérine › Serine endopeptidases › Proprotéine convertase 9 › A
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hydrolysats de protéines › A
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux lipoprotéines › Récepteurs aux lipoprotéines LDL › A