Single brain metastasis versus glioblastoma multiforme: a VOI-based multiparametric analysis for differential diagnosis.
Differential diagnosis
Diffusion
Glioblastoma
Perfusion
Single brain metastasis
Journal
La Radiologia medica
ISSN: 1826-6983
Titre abrégé: Radiol Med
Pays: Italy
ID NLM: 0177625
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
01
07
2021
accepted:
08
03
2022
pubmed:
23
3
2022
medline:
18
5
2022
entrez:
22
3
2022
Statut:
ppublish
Résumé
The authors' purpose was to create a valid multiparametric MRI model for the differential diagnosis between glioblastoma and solitary brain metastasis. Forty-one patients (twenty glioblastomas and twenty-one brain metastases) were retrospectively evaluated. MRIs were analyzed with Olea Sphere According to ROC analysis, the area under the curve was 88%, 78% and 74%, respectively, for mean ADC VOI values of the solid component, the mean and max rCBV values in the perilesional edema and the PSR. The cumulative ROC curve of these parameters reached an area under the curve of 95%. Using perilesional max rCBV > 1.37, PSR > 75% and mean lesional ADC < 1 × 10 Lower values of ADC in the enhancing tumor, a higher percentage of SR in perfusion curves and higher values of rCBV in the peritumoral edema closed to the lesion are strongly indicative of GB than solitary BM.
Identifiants
pubmed: 35316518
doi: 10.1007/s11547-022-01480-x
pii: 10.1007/s11547-022-01480-x
pmc: PMC9098536
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
490-497Subventions
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Informations de copyright
© 2022. The Author(s).
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