Adjuvant Effects of

AIDS Vaccines Adjuvants, Immunologic Animals Flagellin HIV Core Protein p24 HIV-1 Immunization Mice Mice, Inbred BALB C Pseudomonas aeruginosa
HIV-1 vaccine adjuvant flagellin immune responses route of immunization

Journal

Viral immunology
ISSN: 1557-8976
Titre abrégé: Viral Immunol
Pays: United States
ID NLM: 8801552

Informations de publication

Date de publication:
03 2022
Historique:
entrez: 23 3 2022
pubmed: 24 3 2022
medline: 20 4 2022
Statut: ppublish

Résumé

New strategies to increase the immune response to HIV-1 vaccine using immunological adjuvants such as Toll-like receptor agonists are needed. In this study, HIV-1 p24-Nef and conjugated form of the vaccine candidate to type-A flagellin (FLA) were injected in the BALB/c mice in different routes. Two weeks after the last immunization, lymphocyte proliferation was measured by the BrdU method. The IL-4 and IFN-

Identifiants

DOI: 10.1089/vim.2021.0143 PMID: 35319970
pubmed: 35319970
doi: 10.1089/vim.2021.0143
doi:

Substances chimiques

AIDS Vaccines 0
Adjuvants, Immunologic 0
HIV Core Protein p24 0
Flagellin 12777-81-0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

150-158

Auteurs

Arezou Rezaei (A)

Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Ghorbanali Shahabi (G)

Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Sobhan Faezi (S)

Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Medical Biotechnology Research Center, School of Paramedicine; Guilan University of Medical Sciences, Rasht, Iran.

Mehdi Shafiee Ardestani (M)

Department of Radiopharmacy, Faculty of Pharmacy; Tehran University of Medical Sciences, Tehran, Iran.

Hedayatollah Shirzad (H)

Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Kayhan Azadmanesh (K)

Department of Virology, Pasteur Institute of Iran, Tehran, Iran.

Ebrahim Mirzajani (E)

Department of Biochemistry, School of Medicine; Guilan University of Medical Sciences, Rasht, Iran.

Arezoo Shajiei (A)

Department of Virology, Pasteur Institute of Iran, Tehran, Iran.

Mehdi Mahdavi (M)

Advanced Therapy Medicinal Product (ATMP) Department, Breast Cancer Research Center, Motamed Cancer Institute, Academic Center for Education, Culture and Research (ACECR), Tehran, Iran.
Department of Immunology, Pasteur Institute of Iran, Tehran, Iran.
Immunotherapy Group, The Institute of Pharmaceutical Sciences (TIPS); Tehran University of Medical Sciences, Tehran, Iran.
Recombinant Vaccine Research Center, Faculty of Pharmacy; Tehran University of Medical Sciences, Tehran, Iran.
ORCID: 0000-0003-4478-5957

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Classifications MeSH

questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins antiviraux › Vaccins contre le SIDA › Adjuvant Effects of
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Adjuvants immunologiques › Adjuvant Effects of
questionsmedicales.fr › Eucaryotes › Animaux › Adjuvant Effects of
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Flagelline › Adjuvant Effects of
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes viraux › Antigènes du VIH › Protéine de capside p24 du VIH › Adjuvant Effects of
questionsmedicales.fr › Virus › Virus à ARN › Retroviridae › Lentivirus › Lentivirus des primates › VIH (Virus de l'Immunodéficience Humaine) › VIH-1 (Virus de l'Immunodéficience Humaine de type 1) › Adjuvant Effects of
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Immunisation › Adjuvant Effects of
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Adjuvant Effects of
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée BALB C › Adjuvant Effects of
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Pseudomonadaceae › Pseudomonas › Pseudomonas aeruginosa › Adjuvant Effects of