Neoechinulin A as a Promising SARS-CoV-2 M
Alkaloids
/ chemistry
Antiviral Agents
/ chemistry
Aspergillus fumigatus
/ chemistry
Coronavirus 3C Proteases
/ antagonists & inhibitors
Cysteine Proteinase Inhibitors
/ chemistry
Indole Alkaloids
/ chemistry
Molecular Docking Simulation
Molecular Dynamics Simulation
Piperazines
/ chemistry
SARS-CoV-2
/ enzymology
Aspergillus fumigatus
SARS-CoV-2 Mpro
molecular docking
neoechinulin A
steered molecular dynamics simulation
Journal
Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729
Informations de publication
Date de publication:
24 Feb 2022
24 Feb 2022
Historique:
received:
27
01
2022
revised:
21
02
2022
accepted:
22
02
2022
entrez:
24
3
2022
pubmed:
25
3
2022
medline:
29
3
2022
Statut:
epublish
Résumé
The COVID-19 pandemic and its continuing emerging variants emphasize the need to discover appropriate treatment, where vaccines alone have failed to show complete protection against the new variants of the virus. Therefore, treatment of the infected cases is critical. This paper discusses the bio-guided isolation of three indole diketopiperazine alkaloids, neoechinulin A (
Identifiants
pubmed: 35323462
pii: md20030163
doi: 10.3390/md20030163
pmc: PMC8955780
pii:
doi:
Substances chimiques
Alkaloids
0
Antiviral Agents
0
Cysteine Proteinase Inhibitors
0
Indole Alkaloids
0
Piperazines
0
eurocristatine
0
neoechinulin A
0
echinuline
3DP19VPN8U
Coronavirus 3C Proteases
EC 3.4.22.28
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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