Donor-derived duodenal adenocarcinoma of a bladder-drained pancreas allograft.
cancer/malignancy/neoplasia
cancer/malignancy/neoplasia: risk factors
clinical research/practice
pancreas/simultaneous pancreas-kidney transplantation
pathology/histopathology
urinalysis
urology
Journal
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
ISSN: 1600-6143
Titre abrégé: Am J Transplant
Pays: United States
ID NLM: 100968638
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
revised:
16
03
2022
received:
14
01
2022
accepted:
21
03
2022
pubmed:
25
3
2022
medline:
1
9
2022
entrez:
24
3
2022
Statut:
ppublish
Résumé
The subset of the population that received bladder-drained allograft pancreata during peak utilization of the technique in the 1990s is approaching 20-30 postoperative years. This time frame is salient, as it parallels the time in which patients in the urologic literature develop adenocarcinomas after bladder reconstruction using gastrointestinal segments. We present the case of a 57-year-old simultaneous pancreas/kidney recipient who presented with microhematuria twenty-four years after transplantation and was found to have an adenocarcinoma of the duodenum of his failed, bladder-drained pancreas. After allograft pancreatectomy/duodenectomy, he remains disease-free eleven months postoperatively. As this patient population ages, practitioners should consider pathology of the donor duodenum and pancreas in recipients who present with gross or microscopic hematuria.
Identifiants
pubmed: 35325501
doi: 10.1111/ajt.17042
pmc: PMC9543768
pii: S1600-6135(22)29921-3
doi:
Types de publication
Case Reports
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2265-2268Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2022 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons.
Références
Clin Transplant. 2005 Aug;19(4):433-55
pubmed: 16008587
Urol Clin North Am. 2018 Feb;45(1):91-99
pubmed: 29169454
Transplant Direct. 2020 Dec 08;7(1):e636
pubmed: 33324741
Eur Urol. 2011 Nov;60(5):1081-6
pubmed: 21802831
Transplant Proc. 2017 Dec;49(10):2352-2354
pubmed: 29198676
Gastroenterol Clin North Am. 2018 Jun;47(2):417-441
pubmed: 29735033
JAMA. 2011 Nov 2;306(17):1891-901
pubmed: 22045767
BMJ Case Rep. 2012 Apr 28;2012:
pubmed: 22605000
Med Sci (Basel). 2019 Mar 17;7(3):
pubmed: 30884915
Am J Transplant. 2021 Feb;21(2):689-702
pubmed: 32627325
Transplantation. 2001 Sep 27;72(6):1156-7
pubmed: 11579317
CMAJ. 2018 Apr 9;190(14):E422-E429
pubmed: 29632037
Am J Transplant. 2022 Sep;22(9):2265-2268
pubmed: 35325501
Am J Transplant. 2011 Jun;11(6):1123-30
pubmed: 21443676
BJU Int. 2009 Aug;104(3):392-5
pubmed: 19239457
J Urol. 2011 Oct;186(4):1437-43
pubmed: 21855939
Gut. 2002 Oct;51 Suppl 5:V15-6
pubmed: 12221034