A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively.


Journal

Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052

Informations de publication

Date de publication:
17 03 2022
Historique:
received: 20 12 2021
revised: 25 02 2022
accepted: 08 03 2022
entrez: 25 3 2022
pubmed: 26 3 2022
medline: 13 4 2022
Statut: epublish

Résumé

The

Identifiants

pubmed: 35326469
pii: cells11061018
doi: 10.3390/cells11061018
pmc: PMC8946913
pii:
doi:

Substances chimiques

LRRK2 protein, human EC 2.7.11.1
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 EC 2.7.11.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Agence Nationale de la Recherche
ID : ANR-16-CE16-0012-02
Organisme : Agence Nationale de la Recherche
ID : ANR-20-CE16-0008
Organisme : Agence Nationale de la Recherche
ID : ANR-21-CE16 PARK-PEP
Organisme : Fondation de France
ID : R19199EK
Organisme : France Parkinson
ID : R16008
Organisme : Michael J. Fox Foundation
ID : 6709.03
Organisme : Michael J. Fox Foundation
ID : 10255.03
Organisme : Michael J. Fox Foundation
ID : 12938.04

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Auteurs

Antoine Marchand (A)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

Alessia Sarchione (A)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

Panagiotis S Athanasopoulos (PS)

Department of Cell Biochemistry, University of Groningen, 9747 AG Groningen, The Netherlands.

Hélène Bauderlique-Le Roy (HB)

BioImaging Center Lille, UMS 2014-US 41-PLBS, F-59000 Lille, France.

Liesel Goveas (L)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

Romain Magnez (R)

University of Lille, CNRS, Inserm, CHU Lille, UMR9020-UMR1277-Canther-Cancer Heterogeneity Plasticity and Resistance to Therapies, Platform of Integrative Chemical Biology, F-59000 Lille, France.

Matthieu Drouyer (M)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

Marco Emanuele (M)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

Franz Y Ho (FY)

Department of Cell Biochemistry, University of Groningen, 9747 AG Groningen, The Netherlands.

Maxime Liberelle (M)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

Patricia Melnyk (P)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

Nicolas Lebègue (N)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

Xavier Thuru (X)

University of Lille, CNRS, Inserm, CHU Lille, UMR9020-UMR1277-Canther-Cancer Heterogeneity Plasticity and Resistance to Therapies, Platform of Integrative Chemical Biology, F-59000 Lille, France.

R Jeremy Nichols (RJ)

Department of Pathology, Stanford University, Stanford, CA 94305, USA.

Elisa Greggio (E)

Physiology, Genetics and Behavior Unit, Department of Biology, University of Padova, 35131 Padova, Italy.

Arjan Kortholt (A)

Department of Cell Biochemistry, University of Groningen, 9747 AG Groningen, The Netherlands.

Thierry Galli (T)

Institute of Psychiatry and Neuroscience of Paris, Université Paris Cité, INSERM U1266, F-75014 Paris, France.
GHU-Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, F-75014 Paris, France.

Marie-Christine Chartier-Harlin (MC)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

Jean-Marc Taymans (JM)

University of Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience and Cognition, F-59000 Lille, France.

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