Elisa Greggio

Affiliations

Laboratory of Cellular Physiology and Molecular Biophysics, Department of Biology, University of Padua, Padua, Italy.

Publications (33)

Ceramides in Parkinson's Disease: From Recent Evidence to New Hypotheses.

Frontiers in neuroscience

Avec: Nicoletta Plotegher , Luigi Bubacco , Elisa Greggio , Laura Civiero

Kinase activity of mutant LRRK2 manifests differently in hetero-dimeric vs. homo-dimeric complexes.

The Biochemical journal

Avec: Emmanouela Leandrou , Eliana Markidi , Anna Memou , Katerina Melachroinou , Elisa Greggio , Hardy J Rideout

Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites.

Journal of neurochemistry

Avec: Antonella Marte , Isabella Russo , Claudia Rebosio , Pierluigi Valente , Elisa Belluzzi , Francesca Pischedda , Caterina Montani , Chiara Lavarello , Andrea Petretto , Ernesto Fedele , Pietro Baldelli , Fabio Benfenati , Giovanni Piccoli , Elisa Greggio , Franco Onofri

Pathways to Parkinson's disease: a spotlight on 14-3-3 proteins.

NPJ Parkinson's disease

Avec: E Giusto , T A Yacoubian , E Greggio , L Civiero

PAK6-mediated phosphorylation of PPP2R2C regulates LRRK2-PP2A complex formation.

Frontiers in molecular neuroscience

Avec: Lucia Iannotta , Marco Emanuele , Giulia Favetta , Giulia Tombesi , Laurine Vandewynckel , Antonio Jesús Lara Ordóñez , Jean-Michel Saliou , Matthieu Drouyer , William Sibran , Laura Civiero , R Jeremy Nichols , Panagiotis S Athanasopoulos , Arjan Kortholt , Marie-Christine Chartier-Harlin , Elisa Greggio , Jean-Marc Taymans

DJ-1 promotes energy balance by regulating both mitochondrial and autophagic homeostasis.

Neurobiology of disease

Avec: Federica De Lazzari , Francesco Agostini , Nicoletta Plotegher , Michele Sandre , Elisa Greggio , Aram Megighian , Luigi Bubacco , Federica Sandrelli , Alexander J Whitworth , Marco Bisaglia

LRRK2 signaling in neurodegeneration: two decades of progress.

Essays in biochemistry

Avec: Lucia Iannotta , Elisa Greggio

LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation.

Brain : a journal of neurology

Avec: Francesca Pischedda , Maria Daniela Cirnaru , Luisa Ponzoni , Michele Sandre , Alice Biosa , Maria Perez Carrion , Oriano Marin , Michele Morari , Lifeng Pan , Elisa Greggio , Rina Bandopadhyay , Mariaelvina Sala , Giovanni Piccoli

Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues.

Cells

Avec: Lucia Iannotta , Alice Biosa , Jillian H Kluss , Giulia Tombesi , Alice Kaganovich , Susanna Cogo , Nicoletta Plotegher , Laura Civiero , Evy Lobbestael , Veerle Baekelandt , Mark R Cookson , Elisa Greggio

Prospective Role of PAK6 and 14-3-3γ as Biomarkers for Parkinson's Disease.

Journal of Parkinson's disease

Avec: Elena Giusto , Lorenza Maistrello , Lucia Iannotta , Veronica Giusti , Ludovica Iovino , Rina Bandopadhyay , Angelo Antonini , Luigi Bubacco , Rita Barresi , Nicoletta Plotegher , Elisa Greggio , Laura Civiero

LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons.

bioRxiv : the preprint server for biology

Avec: Chuyu Chen , Meghan Masotti , Nathaniel Shepard , Vanessa Promes , Giulia Tombesi , Daniel Arango , Claudia Manzoni , Elisa Greggio , Sabine Hilfiker , Yevgenia Kozorovitskiy , Loukia Parisiadou

Leucine-rich repeat kinase 2 and lysosomal dyshomeostasis in Parkinson disease.

Journal of neurochemistry

Avec: Susanna Cogo , Claudia Manzoni , Patrick A Lewis , Elisa Greggio

Too much for your own good: Excessive dopamine damages neurons and contributes to Parkinson's disease: An Editorial Highlight for "Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo".

Journal of neurochemistry

Avec: Anna Masato , Luigi Bubacco , Elisa Greggio

Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson's disease.

Acta neuropathologica

Avec: Ludovica Iovino , Veronica Giusti , Francesca Pischedda , Elena Giusto , Nicoletta Plotegher , Antonella Marte , Ilaria Battisti , Angela Di Iacovo , Algerta Marku , Giovanni Piccoli , Rina Bandopadhyay , Carla Perego , Tiziana Bonifacino , Giambattista Bonanno , Cristina Roseti , Elena Bossi , Giorgio Arrigoni , Luigi Bubacco , Elisa Greggio , Sabine Hilfiker , Laura Civiero

LRRK2 as a target for modulating immune system responses.

Neurobiology of disease

Avec: Isabella Russo , Luigi Bubacco , Elisa Greggio

Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins.

Neurobiology of disease

Avec: Susanna Cogo , James E Tomkins , Nikoleta Vavouraki , Veronica Giusti , Federica Forcellato , Cinzia Franchin , Isabella Tessari , Giorgio Arrigoni , Laura Cendron , Claudia Manzoni , Laura Civiero , Patrick A Lewis , Elisa Greggio

DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease.

NPJ Parkinson's disease

Avec: Anna Masato , Nicoletta Plotegher , Francesca Terrin , Michele Sandre , Gaia Faustini , Andrea Thor , Stephen Adams , Giulia Berti , Susanna Cogo , Federica De Lazzari , Camilla Maria Fontana , Paul Anthony Martinez , Randy Strong , Rina Bandopadhyay , Marco Bisaglia , Arianna Bellucci , Elisa Greggio , Luisa Dalla Valle , Daniela Boassa , Luigi Bubacco

Sequestosome-1 (SQSTM1/p62) as a target in dopamine catabolite-mediated cellular dyshomeostasis.

Cell death & disease

Avec: Anna Masato , Annapaola Andolfo , Giulia Favetta , Edoardo Niccolò Bellini , Susanna Cogo , Luisa Dalla Valle , Daniela Boassa , Elisa Greggio , Nicoletta Plotegher , Luigi Bubacco

PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner.

Cell death & disease

Avec: Lucia Iannotta , Rachel Fasiczka , Giulia Favetta , Yibo Zhao , Elena Giusto , Elena Dall'Ara , Jianning Wei , Franz Y Ho , Claudia Ciriani , Susanna Cogo , Isabella Tessari , Ciro Iaccarino , Maxime Liberelle , Luigi Bubacco , Jean-Marc Taymans , Claudia Manzoni , Arjan Kortholt , Laura Civiero , Sabine Hilfiker , Michael L Lu , Elisa Greggio

Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes.

Glia

Avec: Alice Filippini , Veronica Mutti , Gaia Faustini , Francesca Longhena , Ileana Ramazzina , Federica Rizzi , Alice Kaganovich , Dorien A Roosen , Natalie Landeck , Megan Duffy , Isabella Tessari , Federica Bono , Chiara Fiorentini , Elisa Greggio , Luigi Bubacco , Arianna Bellucci , Mariacristina Missale , Mark R Cookson , Massimo Gennarelli , Isabella Russo

Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype.

Journal of cellular and molecular medicine

Avec: Mauro Rassu , Alice Biosa , Manuela Galioto , Milena Fais , Paola Sini , Elisa Greggio , Giovanni Piccoli , Claudia Crosio , Ciro Iaccarino

Co-occurring WARS2 and CHRNA6 mutations in a child with a severe form of infantile parkinsonism.

Parkinsonism & related disorders

Avec: Simone Martinelli , Viviana Cordeddu , Serena Galosi , Ambra Lanzo , Eleonora Palma , Luca Pannone , Andrea Ciolfi , Michela Di Nottia , Teresa Rizza , Gianfranco Bocchinfuso , Alice Traversa , Viviana Caputo , Andrea Farrotti , Claudia Carducci , Laura Bernardini , Susanna Cogo , Maria Paglione , Martina Venditti , Annarita Bentivoglio , Joanne Ng , Manju A Kurian , Laura Civiero , Elisa Greggio , Lorenzo Stella , Flavia Trettel , Miriam Sciaccaluga , Cristina Roseti , Rosalba Carrozzo , Sergio Fucile , Cristina Limatola , Elia Di Schiavi , Marco Tartaglia , Vincenzo Leuzzi

The Roc domain of LRRK2 as a hub for protein-protein interactions: a focus on PAK6 and its impact on RAB phosphorylation.

Brain research

Avec: Susanna Cogo , Franz Y Ho , Elena Tosoni , James E Tomkins , Isabella Tessari , Lucia Iannotta , Thomas J Montine , Claudia Manzoni , Patrick A Lewis , Luigi Bubacco , Marie-Christine Chartier Harlin , Jean-Marc Taymans , Arjan Kortholt , Jeremy Nichols , Laura Cendron , Laura Civiero , Elisa Greggio

LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease.

NPJ Parkinson's disease

Avec: Maria Kedariti , Emanuele Frattini , Pascale Baden , Susanna Cogo , Laura Civiero , Elena Ziviani , Gianluca Zilio , Federico Bertoli , Massimo Aureli , Alice Kaganovich , Mark R Cookson , Leonidas Stefanis , Matthew Surface , Michela Deleidi , Alessio Di Fonzo , Roy N Alcalay , Hardy Rideout , Elisa Greggio , Nicoletta Plotegher

Inhibition of the Exocyst Complex Attenuates the LRRK2 Pathological Effects.

International journal of molecular sciences

Avec: Cristina Ciampelli , Grazia Galleri , Silvia Puggioni , Milena Fais , Lucia Iannotta , Manuela Galioto , Marta Becciu , Elisa Greggio , Roberto Bernardoni , Claudia Crosio , Ciro Iaccarino

The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A.

The Journal of biological chemistry

Avec: Pilar Rivero-Ríos , María Romo-Lozano , Jesús Madero-Pérez , Andrew P Thomas , Alice Biosa , Elisa Greggio , Sabine Hilfiker

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils.

Neurobiology of disease

Avec: Isabella Russo , Alice Kaganovich , Jinhui Ding , Natalie Landeck , Adamantios Mamais , Tatiana Varanita , Alice Biosa , Isabella Tessari , Luigi Bubacco , Elisa Greggio , Mark R Cookson

Parkinson's Disease-Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance.

Molecular neurobiology

Avec: Linn Streubel-Gallasch , Veronica Giusti , Michele Sandre , Isabella Tessari , Nicoletta Plotegher , Elena Giusto , Anna Masato , Ludovica Iovino , Ilaria Battisti , Giorgio Arrigoni , Derya Shimshek , Elisa Greggio , Marie-Eve Tremblay , Luigi Bubacco , Anna Erlandsson , Laura Civiero

A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively.

Cells

Avec: Antoine Marchand , Alessia Sarchione , Panagiotis S Athanasopoulos , Hélène Bauderlique-Le Roy , Liesel Goveas , Romain Magnez , Matthieu Drouyer , Marco Emanuele , Franz Y Ho , Maxime Liberelle , Patricia Melnyk , Nicolas Lebègue , Xavier Thuru , R Jeremy Nichols , Elisa Greggio , Arjan Kortholt , Thierry Galli , Marie-Christine Chartier-Harlin , Jean-Marc Taymans

The Regulation of MiTF/TFE Transcription Factors Across Model Organisms: from Brain Physiology to Implication for Neurodegeneration.

Molecular neurobiology

Avec: Francesco Agostini , Rossella Agostinis , Diego L Medina , Marco Bisaglia , Elisa Greggio , Nicoletta Plotegher

Leucine-rich repeat kinase 2 (LRRK2): an update on the potential therapeutic target for Parkinson's disease.

Expert opinion on therapeutic targets

Avec: Jillian H Kluss , Patrick A Lewis , Elisa Greggio

Evaluation of UVC Excimer Lamp (222 nm) Efficacy for Coronavirus Inactivation in an Animal Model.

Viruses

Avec: Claudia Maria Tucciarone , Mattia Cecchinato , Lucrezia Vianello , Gabriele Simi , Enrico Borsato , Luca Silvestrin , Michele Giorato , Cristiano Salata , Mauro Morandin , Elisa Greggio , Michele Drigo

Investigation of microglial diversity in a LRRK2 G2019S mouse model of Parkinson's disease.

Neurobiology of disease

Avec: L Iovino , J Vander Zwaag , G Kaur , M Khakpour , V Giusti , M Donadon , A Chiavegato , L Tenorio-Lopes , E Greggio , M E Tremblay , L Civiero

Réseau de co-auteurs

Luigi Bubacco 13 collaborations

Laura Civiero 11 collaborations

Nicoletta Plotegher 10 collaborations

Susanna Cogo 9 collaborations

Lucia Iannotta 7 collaborations

Isabella Tessari 6 collaborations

Alice Biosa 5 collaborations

Claudia Manzoni 5 collaborations

Isabella Russo 4 collaborations

Giovanni Piccoli 4 collaborations

Arjan Kortholt 4 collaborations

Jean-Marc Taymans 4 collaborations

Michele Sandre 4 collaborations

Rina Bandopadhyay 4 collaborations

Alice Kaganovich 4 collaborations

Mark R Cookson 4 collaborations

Elena Giusto 4 collaborations

Veronica Giusti 4 collaborations

Sabine Hilfiker 4 collaborations

Patrick A Lewis 4 collaborations

Anna Masato 4 collaborations

Francesca Pischedda 3 collaborations

Giulia Favetta 3 collaborations

Giulia Tombesi 3 collaborations

Marco Bisaglia 3 collaborations

Ludovica Iovino 3 collaborations

Giorgio Arrigoni 3 collaborations

Franz Y Ho 3 collaborations

Ciro Iaccarino 3 collaborations

Antonella Marte 2 collaborations

E Greggio 2 collaborations

L Civiero 2 collaborations

Marco Emanuele 2 collaborations

Matthieu Drouyer 2 collaborations

R Jeremy Nichols 2 collaborations

Panagiotis S Athanasopoulos 2 collaborations

Marie-Christine Chartier-Harlin 2 collaborations

Federica De Lazzari 2 collaborations

Francesco Agostini 2 collaborations

Jillian H Kluss 2 collaborations

Ilaria Battisti 2 collaborations

Cristina Roseti 2 collaborations

James E Tomkins 2 collaborations

Laura Cendron 2 collaborations

Gaia Faustini 2 collaborations

Arianna Bellucci 2 collaborations

Luisa Dalla Valle 2 collaborations

Daniela Boassa 2 collaborations

Maxime Liberelle 2 collaborations

Natalie Landeck 2 collaborations

Manuela Galioto 2 collaborations

Milena Fais 2 collaborations

Claudia Crosio 2 collaborations

Emmanouela Leandrou 1 collaboration

Eliana Markidi 1 collaboration

Anna Memou 1 collaboration

Katerina Melachroinou 1 collaboration

Hardy J Rideout 1 collaboration

Claudia Rebosio 1 collaboration

Pierluigi Valente 1 collaboration

Elisa Belluzzi 1 collaboration

Caterina Montani 1 collaboration

Chiara Lavarello 1 collaboration

Andrea Petretto 1 collaboration

Ernesto Fedele 1 collaboration

Pietro Baldelli 1 collaboration

Fabio Benfenati 1 collaboration

Franco Onofri 1 collaboration

E Giusto 1 collaboration

T A Yacoubian 1 collaboration

Laurine Vandewynckel 1 collaboration

Antonio Jesús Lara Ordóñez 1 collaboration

Jean-Michel Saliou 1 collaboration

William Sibran 1 collaboration

Aram Megighian 1 collaboration

Federica Sandrelli 1 collaboration

Alexander J Whitworth 1 collaboration

Maria Daniela Cirnaru 1 collaboration

Luisa Ponzoni 1 collaboration

Maria Perez Carrion 1 collaboration

Oriano Marin 1 collaboration

Michele Morari 1 collaboration

Lifeng Pan 1 collaboration

Mariaelvina Sala 1 collaboration

Evy Lobbestael 1 collaboration

Veerle Baekelandt 1 collaboration

Lorenza Maistrello 1 collaboration

Angelo Antonini 1 collaboration

Rita Barresi 1 collaboration

Chuyu Chen 1 collaboration

Meghan Masotti 1 collaboration

Nathaniel Shepard 1 collaboration

Vanessa Promes 1 collaboration

Daniel Arango 1 collaboration

Yevgenia Kozorovitskiy 1 collaboration

Loukia Parisiadou 1 collaboration

Angela Di Iacovo 1 collaboration

Algerta Marku 1 collaboration

Carla Perego 1 collaboration

Tiziana Bonifacino 1 collaboration

Giambattista Bonanno 1 collaboration

Elena Bossi 1 collaboration

Nikoleta Vavouraki 1 collaboration

Federica Forcellato 1 collaboration

Cinzia Franchin 1 collaboration

Francesca Terrin 1 collaboration

Andrea Thor 1 collaboration

Stephen Adams 1 collaboration

Giulia Berti 1 collaboration

Camilla Maria Fontana 1 collaboration

Paul Anthony Martinez 1 collaboration

Randy Strong 1 collaboration

Annapaola Andolfo 1 collaboration

Edoardo Niccolò Bellini 1 collaboration

Rachel Fasiczka 1 collaboration

Yibo Zhao 1 collaboration

Elena Dall'Ara 1 collaboration

Jianning Wei 1 collaboration

Claudia Ciriani 1 collaboration

Michael L Lu 1 collaboration

Alice Filippini 1 collaboration

Veronica Mutti 1 collaboration

Francesca Longhena 1 collaboration

Ileana Ramazzina 1 collaboration

Federica Rizzi 1 collaboration

Dorien A Roosen 1 collaboration

Megan Duffy 1 collaboration

Federica Bono 1 collaboration

Chiara Fiorentini 1 collaboration

Mariacristina Missale 1 collaboration

Massimo Gennarelli 1 collaboration

Mauro Rassu 1 collaboration

Paola Sini 1 collaboration

Simone Martinelli 1 collaboration

Viviana Cordeddu 1 collaboration

Serena Galosi 1 collaboration

Ambra Lanzo 1 collaboration

Eleonora Palma 1 collaboration

Luca Pannone 1 collaboration

Andrea Ciolfi 1 collaboration

Michela Di Nottia 1 collaboration

Teresa Rizza 1 collaboration

Gianfranco Bocchinfuso 1 collaboration

Alice Traversa 1 collaboration

Viviana Caputo 1 collaboration

Andrea Farrotti 1 collaboration

Claudia Carducci 1 collaboration

Laura Bernardini 1 collaboration

Maria Paglione 1 collaboration

Martina Venditti 1 collaboration

Annarita Bentivoglio 1 collaboration

Joanne Ng 1 collaboration

Manju A Kurian 1 collaboration

Lorenzo Stella 1 collaboration

Flavia Trettel 1 collaboration

Miriam Sciaccaluga 1 collaboration

Rosalba Carrozzo 1 collaboration

Sergio Fucile 1 collaboration

Cristina Limatola 1 collaboration

Elia Di Schiavi 1 collaboration

Marco Tartaglia 1 collaboration

Vincenzo Leuzzi 1 collaboration

Elena Tosoni 1 collaboration

Thomas J Montine 1 collaboration

Marie-Christine Chartier Harlin 1 collaboration

Jeremy Nichols 1 collaboration

Maria Kedariti 1 collaboration

Emanuele Frattini 1 collaboration

Pascale Baden 1 collaboration

Elena Ziviani 1 collaboration

Gianluca Zilio 1 collaboration

Federico Bertoli 1 collaboration

Massimo Aureli 1 collaboration

Leonidas Stefanis 1 collaboration

Matthew Surface 1 collaboration

Michela Deleidi 1 collaboration

Alessio Di Fonzo 1 collaboration

Roy N Alcalay 1 collaboration

Hardy Rideout 1 collaboration

Cristina Ciampelli 1 collaboration

Grazia Galleri 1 collaboration

Silvia Puggioni 1 collaboration

Marta Becciu 1 collaboration

Roberto Bernardoni 1 collaboration

Pilar Rivero-Ríos 1 collaboration

María Romo-Lozano 1 collaboration

Jesús Madero-Pérez 1 collaboration

Andrew P Thomas 1 collaboration

Jinhui Ding 1 collaboration

Adamantios Mamais 1 collaboration

Tatiana Varanita 1 collaboration

Linn Streubel-Gallasch 1 collaboration

Derya Shimshek 1 collaboration

Marie-Eve Tremblay 1 collaboration

Anna Erlandsson 1 collaboration

Antoine Marchand 1 collaboration

Alessia Sarchione 1 collaboration

Hélène Bauderlique-Le Roy 1 collaboration

Liesel Goveas 1 collaboration

Romain Magnez 1 collaboration

Patricia Melnyk 1 collaboration

Nicolas Lebègue 1 collaboration

Xavier Thuru 1 collaboration

Thierry Galli 1 collaboration

Rossella Agostinis 1 collaboration

Diego L Medina 1 collaboration

Claudia Maria Tucciarone 1 collaboration

Mattia Cecchinato 1 collaboration

Lucrezia Vianello 1 collaboration

Gabriele Simi 1 collaboration

Enrico Borsato 1 collaboration

Luca Silvestrin 1 collaboration

Michele Giorato 1 collaboration

Cristiano Salata 1 collaboration

Mauro Morandin 1 collaboration

Michele Drigo 1 collaboration

L Iovino 1 collaboration

J Vander Zwaag 1 collaboration

G Kaur 1 collaboration

M Khakpour 1 collaboration

V Giusti 1 collaboration

M Donadon 1 collaboration

A Chiavegato 1 collaboration

L Tenorio-Lopes 1 collaboration

M E Tremblay 1 collaboration