Francesca Longhena

Affiliations

Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.

Publications (21)

NF-κB/c-Rel deficiency causes Parkinson's disease-like prodromal symptoms and progressive pathology in mice.

Translational neurodegeneration

Avec: Edoardo Parrella , Arianna Bellucci , Vanessa Porrini , Marina Benarese , Annamaria Lanzillotta , Gaia Faustini , Francesca Longhena , Giulia Abate , Daniela Uberti , Marina Pizzi

Dopamine signaling modulates microglial NLRP3 inflammasome activation: implications for Parkinson's disease.

Journal of neuroinflammation

Avec: Adrianne F Pike , Francesca Longhena , Gaia Faustini , Jean-Marc van Eik , Iris Gombert , Maaike A C Herrebout , Mona M H E Fayed , Michele Sandre , Tatiana Varanita , Charlotte E Teunissen , Jeroen J M Hoozemans , Arianna Bellucci , Robert Veerhuis , Luigi Bubacco

Acetylated α-Tubulin and α-Synuclein: Physiological Interplay and Contribution to α-Synuclein Oligomerization.

International journal of molecular sciences

Avec: Alessandra Maria Calogero , Milo Jarno Basellini , Huseyin Berkcan Isilgan , Francesca Longhena , Arianna Bellucci , Samanta Mazzetti , Chiara Rolando , Gianni Pezzoli , Graziella Cappelletti

Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate.

Neurobiology of disease

Avec: Gaia Faustini , Francesca Longhena , Agostino Bruno , Federica Bono , Jessica Grigoletto , Luca La Via , Alessandro Barbon , Andrea Casiraghi , Valentina Straniero , Ermanno Valoti , Gabriele Costantino , Fabio Benfenati , Cristina Missale , Marina Pizzi , Maria Grazia Spillantini , Arianna Bellucci

Abiraterone acetate exerts a cytotoxic effect in human prostate cancer cell lines.

Naunyn-Schmiedeberg's archives of pharmacology

Avec: Martina Fragni , Diego Galli , Marco Nardini , Elisa Rossini , Sara Vezzoli , Matteo Zametta , Francesca Longhena , Arianna Bellucci , Elisa Roca , Maurizio Memo , Alfredo Berruti , Sandra Sigala

Alpha synuclein post translational modifications: potential targets for Parkinson's disease therapy?

Frontiers in molecular neuroscience

Avec: Viviana Brembati , Gaia Faustini , Francesca Longhena , Arianna Bellucci

Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson's Disease.

International journal of molecular sciences

Avec: Viviana Brembati , Gaia Faustini , Francesca Longhena , Tiago Fleming Outeiro , Arianna Bellucci

Nuclear Factor-κB Dysregulation and α-Synuclein Pathology: Critical Interplay in the Pathogenesis of Parkinson's Disease.

Frontiers in aging neuroscience

Avec: Arianna Bellucci , Luigi Bubacco , Francesca Longhena , Edoardo Parrella , Gaia Faustini , Vanessa Porrini , Federica Bono , Cristina Missale , Marina Pizzi

Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates.

Cells

Avec: Gaia Faustini , Francesca Longhena , Alessia Muscò , Federica Bono , Edoardo Parrella , Luca La Via , Alessandro Barbon , Marina Pizzi , Franco Onofri , Fabio Benfenati , Cristina Missale , Maurizio Memo , Daniela Zizioli , Arianna Bellucci

G Protein-Dependent Activation of the PKA-Erk1/2 Pathway by the Striatal Dopamine D1/D3 Receptor Heteromer Involves Beta-Arrestin and the Tyrosine Phosphatase Shp-2.

Biomolecules

Avec: Federica Bono , Zaira Tomasoni , Veronica Mutti , Giulia Sbrini , Rajesh Kumar , Francesca Longhena , Chiara Fiorentini , Cristina Missale

Alpha-Synuclein Preserves Mitochondrial Fusion and Function in Neuronal Cells.

Oxidative medicine and cellular longevity

Avec: Gaia Faustini , Elena Marchesan , Laura Zonta , Federica Bono , Emanuela Bottani , Francesca Longhena , Elena Ziviani , Alessandra Valerio , Arianna Bellucci

Design and Synthesis of Fluorescent Methylphenidate Analogues for a FRET-Based Assay of Synapsin III Binding.

ChemMedChem

Avec: Andrea Casiraghi , Francesca Longhena , Valentina Straniero , Gaia Faustini , Amy H Newman , Arianna Bellucci , Ermanno Valoti

The good and bad of therapeutic strategies that directly target α-synuclein.

IUBMB life

Avec: Francesca Longhena , Gaia Faustini , Viviana Brembati , Marina Pizzi , Arianna Bellucci

An updated reappraisal of synapsins: structure, function and role in neurological and psychiatric disorders.

Neuroscience and biobehavioral reviews

Avec: Francesca Longhena , Gaia Faustini , Viviana Brembati , Marina Pizzi , Fabio Benfenati , Arianna Bellucci

The Role of Rab Proteins in Parkinson's Disease Synaptopathy.

Biomedicines

Avec: Arianna Bellucci , Francesca Longhena , Maria Grazia Spillantini

Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes.

Glia

Avec: Alice Filippini , Veronica Mutti , Gaia Faustini , Francesca Longhena , Ileana Ramazzina , Federica Rizzi , Alice Kaganovich , Dorien A Roosen , Natalie Landeck , Megan Duffy , Isabella Tessari , Federica Bono , Chiara Fiorentini , Elisa Greggio , Luigi Bubacco , Arianna Bellucci , Mariacristina Missale , Mark R Cookson , Massimo Gennarelli , Isabella Russo

Alpha-Synuclein in the Regulation of Brain Endothelial and Perivascular Cells: Gaps and Future Perspectives.

Frontiers in immunology

Avec: Tizibt Ashine Bogale , Gaia Faustini , Francesca Longhena , Stefania Mitola , Marina Pizzi , Arianna Bellucci

Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and Pathology.

International journal of molecular sciences

Avec: Francesca Longhena , Gaia Faustini , Maria Grazia Spillantini , Arianna Bellucci

Synapsin III gene silencing redeems alpha-synuclein transgenic mice from Parkinson's disease-like phenotype.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Gaia Faustini , Francesca Longhena , Anna Masato , Valentina Bassareo , Roberto Frau , Therése Klingstedt , Hamid Shirani , Viviana Brembati , Edoardo Parrella , Marika Vezzoli , K Peter R Nilsson , Marina Pizzi , Maria Grazia Spillantini , Luigi Bubacco , Arianna Bellucci

Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson's Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice.

Pharmaceutics

Avec: Andrea Casiraghi , Francesca Longhena , Gaia Faustini , Giovanni Ribaudo , Lorenzo Suigo , Gisela Andrea Camacho-Hernandez , Federica Bono , Viviana Brembati , Amy Hauck Newman , Alessandra Gianoncelli , Valentina Straniero , Arianna Bellucci , Ermanno Valoti

Nanorod-associated plasmonic circular dichroism monitors the handedness and composition of α-synuclein fibrils from Parkinson's disease models and post-mortem brain.

Nanoscale

Avec: Francesca Longhena , Rihab Boujebene , Viviana Brembati , Michele Sandre , Luigi Bubacco , Sergio Abbate , Giovanna Longhi , Arianna Bellucci

Réseau de co-auteurs

Arianna Bellucci 20 collaborations

Gaia Faustini 16 collaborations

Marina Pizzi 8 collaborations

Federica Bono 7 collaborations

Viviana Brembati 7 collaborations

Luigi Bubacco 5 collaborations

Edoardo Parrella 4 collaborations

Cristina Missale 4 collaborations

Maria Grazia Spillantini 4 collaborations

Andrea Casiraghi 3 collaborations

Valentina Straniero 3 collaborations

Ermanno Valoti 3 collaborations

Fabio Benfenati 3 collaborations

Vanessa Porrini 2 collaborations

Michele Sandre 2 collaborations

Luca La Via 2 collaborations

Alessandro Barbon 2 collaborations

Maurizio Memo 2 collaborations

Veronica Mutti 2 collaborations

Chiara Fiorentini 2 collaborations

Marina Benarese 1 collaboration

Annamaria Lanzillotta 1 collaboration

Giulia Abate 1 collaboration

Daniela Uberti 1 collaboration

Adrianne F Pike 1 collaboration

Jean-Marc van Eik 1 collaboration

Iris Gombert 1 collaboration

Maaike A C Herrebout 1 collaboration

Mona M H E Fayed 1 collaboration

Tatiana Varanita 1 collaboration

Charlotte E Teunissen 1 collaboration

Jeroen J M Hoozemans 1 collaboration

Robert Veerhuis 1 collaboration

Alessandra Maria Calogero 1 collaboration

Milo Jarno Basellini 1 collaboration

Huseyin Berkcan Isilgan 1 collaboration

Samanta Mazzetti 1 collaboration

Chiara Rolando 1 collaboration

Gianni Pezzoli 1 collaboration

Graziella Cappelletti 1 collaboration

Agostino Bruno 1 collaboration

Jessica Grigoletto 1 collaboration

Gabriele Costantino 1 collaboration

Martina Fragni 1 collaboration

Diego Galli 1 collaboration

Marco Nardini 1 collaboration

Elisa Rossini 1 collaboration

Sara Vezzoli 1 collaboration

Matteo Zametta 1 collaboration

Elisa Roca 1 collaboration

Alfredo Berruti 1 collaboration

Sandra Sigala 1 collaboration

Tiago Fleming Outeiro 1 collaboration

Alessia Muscò 1 collaboration

Franco Onofri 1 collaboration

Daniela Zizioli 1 collaboration

Zaira Tomasoni 1 collaboration

Giulia Sbrini 1 collaboration

Rajesh Kumar 1 collaboration

Elena Marchesan 1 collaboration

Laura Zonta 1 collaboration

Emanuela Bottani 1 collaboration

Elena Ziviani 1 collaboration

Alessandra Valerio 1 collaboration

Amy H Newman 1 collaboration

Alice Filippini 1 collaboration

Ileana Ramazzina 1 collaboration

Federica Rizzi 1 collaboration

Alice Kaganovich 1 collaboration

Dorien A Roosen 1 collaboration

Natalie Landeck 1 collaboration

Megan Duffy 1 collaboration

Isabella Tessari 1 collaboration

Elisa Greggio 1 collaboration

Mariacristina Missale 1 collaboration

Mark R Cookson 1 collaboration

Massimo Gennarelli 1 collaboration

Isabella Russo 1 collaboration

Tizibt Ashine Bogale 1 collaboration

Stefania Mitola 1 collaboration

Anna Masato 1 collaboration

Valentina Bassareo 1 collaboration

Roberto Frau 1 collaboration

Therése Klingstedt 1 collaboration

Hamid Shirani 1 collaboration

Marika Vezzoli 1 collaboration

K Peter R Nilsson 1 collaboration

Giovanni Ribaudo 1 collaboration

Lorenzo Suigo 1 collaboration

Gisela Andrea Camacho-Hernandez 1 collaboration

Amy Hauck Newman 1 collaboration

Alessandra Gianoncelli 1 collaboration

Rihab Boujebene 1 collaboration

Sergio Abbate 1 collaboration

Giovanna Longhi 1 collaboration