Identification of Novel Genes Involved in Hyperglycemia in Mice.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
16 Mar 2022
Historique:
received: 29 12 2021
revised: 09 03 2022
accepted: 14 03 2022
entrez: 25 3 2022
pubmed: 26 3 2022
medline: 9 4 2022
Statut: epublish

Résumé

Current attempts to prevent and manage type 2 diabetes have been moderately effective, and a better understanding of the molecular roots of this complex disease is important to develop more successful and precise treatment options. Recently, we initiated the collective diabetes cross, where four mouse inbred strains differing in their diabetes susceptibility were crossed with the obese and diabetes-prone NZO strain and identified the quantitative trait loci (QTL)

Identifiants

pubmed: 35328627
pii: ijms23063205
doi: 10.3390/ijms23063205
pmc: PMC8949927
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : German Ministry of Education and Research and the State of Brandenburg
ID : 82DZD00302

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Auteurs

Wenke Jonas (W)

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.

Oliver Kluth (O)

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.

Anett Helms (A)

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.

Sarah Voß (S)

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.

Markus Jähnert (M)

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.

Pascal Gottmann (P)

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.

Thilo Speckmann (T)

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.

Birgit Knebel (B)

German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.
German Diabetes Center (DDZ), Medical Faculty, Institute for Clinical Biochemistry and Pathobiochemistry, Heinrich Heine University, 40225 Duesseldorf, Germany.

Alexandra Chadt (A)

German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.
German Diabetes Center (DDZ), Medical Faculty, Institute for Clinical Biochemistry and Pathobiochemistry, Heinrich Heine University, 40225 Duesseldorf, Germany.

Hadi Al-Hasani (H)

German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.
German Diabetes Center (DDZ), Medical Faculty, Institute for Clinical Biochemistry and Pathobiochemistry, Heinrich Heine University, 40225 Duesseldorf, Germany.

Annette Schürmann (A)

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.
Institute of Nutritional Sciences, University of Potsdam, 14558 Nuthetal, Germany.

Heike Vogel (H)

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, 85764 München, Germany.
Research Group Genetics of Obesity, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.
Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, 14469 Potsdam, Germany.

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