Identification of Novel Genes Involved in Hyperglycemia in Mice.
QTL
apoptosis
diabetes
proliferation
β-cell
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
16 Mar 2022
16 Mar 2022
Historique:
received:
29
12
2021
revised:
09
03
2022
accepted:
14
03
2022
entrez:
25
3
2022
pubmed:
26
3
2022
medline:
9
4
2022
Statut:
epublish
Résumé
Current attempts to prevent and manage type 2 diabetes have been moderately effective, and a better understanding of the molecular roots of this complex disease is important to develop more successful and precise treatment options. Recently, we initiated the collective diabetes cross, where four mouse inbred strains differing in their diabetes susceptibility were crossed with the obese and diabetes-prone NZO strain and identified the quantitative trait loci (QTL)
Identifiants
pubmed: 35328627
pii: ijms23063205
doi: 10.3390/ijms23063205
pmc: PMC8949927
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : German Ministry of Education and Research and the State of Brandenburg
ID : 82DZD00302
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