Breast cancer morbidity and mortality in rural Ethiopia: data from 788 verbal autopsies.
Breast cancer
Cause of death
Duration of illness
Verbal autopsy
Journal
BMC women's health
ISSN: 1472-6874
Titre abrégé: BMC Womens Health
Pays: England
ID NLM: 101088690
Informations de publication
Date de publication:
24 03 2022
24 03 2022
Historique:
received:
16
06
2021
accepted:
18
03
2022
entrez:
25
3
2022
pubmed:
26
3
2022
medline:
12
4
2022
Statut:
epublish
Résumé
In Ethiopia, breast cancer is the leading cause of cancer among women. Little is known about the duration of disease and symptoms of patients who died from breast cancer in rural Ethiopia. The objective of this study was to assess breast cancer mortality with a particular focus on the self-reported duration of illness including suffering of symptoms, and need for medical care. The cause of death was determined among randomly selected Ethiopian women residing in western Ethiopia. A modified standard verbal autopsy (VA) questionnaire was completed by women whose sisters had died. The questionnaires were reviewed by two independent local physicians to assign a cause of death. We analyzed pattern of cause of deaths, duration of suffering, symptoms, and treatment received. In our study, the age at death was very similar to other population-based data from Ethiopia. We found 32% of 788 deaths were caused by communicable diseases, 12.1% by neoplasms, and 9.4% by pregnancy/maternal mortality. Breast cancer was the second leading neoplasm, responsible for 21 (2.7%) of all deaths (95% CI 1.5-3.7%), and was among the top five causes of non-communicable deaths. The median age of breast cancer death was 37 years, younger than for other causes of death. The median duration of illness with breast cancer was around 1 year. This was substantially more compared to the duration of infectious diseases, but less than the duration of reproductive neoplasms, diabetes, and epilepsy. Breast cancer deaths are common causes of death in women of rural Ethiopia. When assessing the total duration of illness according to specific causes of death, breast and other cancers accounted for a large share of the burden. This has practical implications and highlights the need for palliative care for cancer patients. Substantial efforts are necessary to improve early detection and treatment for breast cancer to reduce premature death in women.
Identifiants
pubmed: 35331210
doi: 10.1186/s12905-022-01672-7
pii: 10.1186/s12905-022-01672-7
pmc: PMC8951700
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
89Informations de copyright
© 2022. The Author(s).
Références
Popul Health Metr. 2017 Jul 1;15(1):22
pubmed: 28666480
JAMA Oncol. 2021 Feb 1;7(2):285-289
pubmed: 33355599
Cancer Epidemiol. 2018 Apr;53:93-98
pubmed: 29414637
J Health Popul Nutr. 2014 Mar;32(1):1-13
pubmed: 24847587
J Oncol. 2010;2010:595167
pubmed: 21253541
Health Policy Plan. 2009 Jul;24(4):312-9
pubmed: 19372240
SSM Popul Health. 2020 Aug 22;12:100653
pubmed: 32939393
PLoS One. 2013;8(4):e59834
pubmed: 23565171
Int J Cancer. 2020 Mar 1;146(5):1208-1218
pubmed: 31087650
Int J Gen Med. 2013 Sep 18;6:787-98
pubmed: 24092994
Cancer. 2005 Apr 15;103(8):1540-50
pubmed: 15768434
S Afr Med J. 2014 May;104(5):377-9
pubmed: 25295328
Cancer. 2010 Feb 1;116(3):577-85
pubmed: 20029968
PLoS Med. 2010 Aug 17;7(8):e1000325
pubmed: 20808956
Cancer Epidemiol Biomarkers Prev. 2015 Oct;24(10):1495-506
pubmed: 26359465
J Glob Oncol. 2018 Sep;4:1-11
pubmed: 30241262
Oncologist. 2021 Jun;26(6):e1009-e1017
pubmed: 33650727
BMC Med Res Methodol. 2012 Aug 28;12:130
pubmed: 22928712
Lancet Glob Health. 2020 Sep;8(9):e1203-e1212
pubmed: 32827482
Lancet Glob Health. 2016 Dec;4(12):e923-e935
pubmed: 27855871
Glob Health Action. 2014 May 15;7:23359
pubmed: 24848653
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
World J Clin Oncol. 2014 Aug 10;5(3):465-77
pubmed: 25114860
Glob Health Action. 2012 Sep 03;5:1-8
pubmed: 22944365