Mentalizing imagery therapy to augment skills training for dementia caregivers: Protocol for a randomized, controlled trial of a mobile application and digital phenotyping.


Journal

Contemporary clinical trials
ISSN: 1559-2030
Titre abrégé: Contemp Clin Trials
Pays: United States
ID NLM: 101242342

Informations de publication

Date de publication:
05 2022
Historique:
received: 27 06 2021
revised: 15 03 2022
accepted: 17 03 2022
pubmed: 26 3 2022
medline: 25 5 2022
entrez: 25 3 2022
Statut: ppublish

Résumé

More than 50 million people worldwide live with a dementia, and most are cared for by family members. Family caregivers often experience chronic stress and insomnia, resulting in decreased mental and physical health. Accessibility of in-person stress reduction therapy is limited due to caregiver time constraints and distance from therapy sites. Mentalizing imagery therapy (MIT) provides mindfulness and guided imagery tools to reduce stress, promote self and other understanding, and increase feelings of interconnectedness. Combining MIT with caregiver skills training might enable caregivers to both reduce stress and better utilize newly learned caregiving skills, but this has never been studied. Delivering MIT through a smartphone application (App) has the potential to overcome difficulties with scalability and dissemination and offers caregivers an easy-to-use format. Harnessing passive smartphone data provides an important opportunity to study behavioral changes continuously and with higher granularity than routine clinical assessments. This protocol describes a randomized, controlled, superiority trial in which 120 family dementia caregivers, aged 60 years or older, will be assigned to smartphone App delivery of caregiver skills with MIT (experimental condition) or without MIT (control condition). The primary objectives of the trial are to assess whether the experimental condition is superior to control on reducing family caregiver stress, insomnia and related outcomes and to demonstrate the feasibility of developing behavioral markers from passive smartphone data that predict health outcomes in older adults. Trial outcomes may inform the suitability of our intervention for caregivers and provide new methods for assessment of older adults.

Identifiants

pubmed: 35331943
pii: S1551-7144(22)00063-5
doi: 10.1016/j.cct.2022.106737
pmc: PMC9133149
mid: NIHMS1794844
pii:
doi:

Types de publication

Clinical Trial Protocol Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

106737

Subventions

Organisme : NIA NIH HHS
ID : K76 AG064390
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG062421
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH118274
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG049692
Pays : United States

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

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Auteurs

Felipe A Jain (FA)

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: felipe.jain@mgh.harvard.edu.

Olivia Okereke (O)

Harvard Medical School, Boston, MA, USA; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Massachusetts Alzheimer's Disease Research Center, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

Laura Gitlin (L)

College of Nursing and Health Professions, Drexel University, Philadelphia, PA, USA.

Paola Pedrelli (P)

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.

Jukka-Pekka Onnela (JP)

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Maren Nyer (M)

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.

Liliana A Ramirez Gomez (LA)

Harvard Medical School, Boston, MA, USA; Massachusetts Alzheimer's Disease Research Center, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA; Multicultural Alzheimer's Prevention Program, Massachusetts General Hospital, Boston, MA, USA.

Michael Pittman (M)

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

Abu Sikder (A)

Innovation Studio, Children's Hospital, Los Angeles, CA, USA.

D J Ursal (DJ)

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

David Mischoulon (D)

Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.

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