Design of protein-binding proteins from the target structure alone.
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
received:
28
09
2021
accepted:
15
03
2022
pubmed:
26
3
2022
medline:
21
5
2022
entrez:
25
3
2022
Statut:
ppublish
Résumé
The design of proteins that bind to a specific site on the surface of a target protein using no information other than the three-dimensional structure of the target remains a challenge
Identifiants
pubmed: 35332283
doi: 10.1038/s41586-022-04654-9
pii: 10.1038/s41586-022-04654-9
pmc: PMC9117152
doi:
Substances chimiques
Amino Acids
0
Carrier Proteins
0
Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, N.I.H., Intramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
551-560Subventions
Organisme : United States Department of Defense | Defense Advanced Research Projects Agency (DARPA)
ID : FA8750-17-C-0219
Organisme : NIGMS NIH HHS
ID : P41 GM103393
Pays : United States
Organisme : NIGMS NIH HHS
ID : P30 GM124165
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI150855
Pays : United States
Organisme : NIGMS NIH HHS
ID : P30 GM138396
Pays : United States
Organisme : NIH HHS
ID : S10 OD012289
Pays : United States
Organisme : U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging)
ID : R01AG063845
Organisme : NIH HHS
ID : S10 OD021527
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI140245
Pays : United States
Organisme : United States Department of Defense | Defense Threat Reduction Agency (DTRA)
ID : HDTRA1-16-C-0029
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG063845
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI150885
Pays : United States
Organisme : NIAID NIH HHS
ID : HHSN272201700059C
Pays : United States
Informations de copyright
© 2022. This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.
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