Female rats are less prone to clinical heart failure than male rats in a juvenile rat model of right ventricular pressure load.

Animals Female Fibrosis Heart Failure / pathology Heart Ventricles Male Rats Ventricular Dysfunction, Right / pathology Ventricular Function, Right Ventricular Pressure
childhood heart failure remodeling right ventricle sex differences

Journal

American journal of physiology. Heart and circulatory physiology
ISSN: 1522-1539
Titre abrégé: Am J Physiol Heart Circ Physiol
Pays: United States
ID NLM: 100901228

Informations de publication

Date de publication:
01 06 2022
Historique:
pubmed: 26 3 2022
medline: 7 5 2022
entrez: 25 3 2022
Statut: ppublish

Résumé

Sex is increasingly emerging as determinant of right ventricular (RV) adaptation to abnormal loading conditions. It is unknown, however, whether sex-related differences already occur in childhood. Therefore, this study aimed to assess sex differences in a juvenile model of early RV pressure load by pulmonary artery banding (PAB) during transition from pre to postpuberty. Rat pups (

Identifiants

DOI: 10.1152/ajpheart.00071.2022 PMID: 35333114
pubmed: 35333114
doi: 10.1152/ajpheart.00071.2022
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

H994-H1002

Auteurs

Guido P L Bossers (GPL)

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
ORCID: 0000-0001-7739-4026

Quint A J Hagdorn (QAJ)

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
ORCID: 0000-0002-4208-1449

Anne-Marie C Koop (AC)

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Diederik E van der Feen (DE)

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

B Bartelds (B)

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Division of Pediatric Cardiology, Department of Pediatrics, Erasmus University Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
ORCID: 0000-0003-3151-2474

Tom van Leusden (T)

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Rudolf A De Boer (RA)

Department of Cardiology, Laboratory for Experimental Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Herman H W Silljé (HHW)

Department of Cardiology, Laboratory for Experimental Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Rolf M F Berger (RMF)

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Female rats are less prone to clinical heart...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Female rats are less prone to clinical heart...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Défaillance cardiaque › Female rats are less prone to clinical heart...
questionsmedicales.fr › Système cardiovasculaire › Coeur › Ventricules cardiaques › Female rats are less prone to clinical heart...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Female rats are less prone to clinical heart...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Dysfonction ventriculaire › Dysfonction ventriculaire droite › Female rats are less prone to clinical heart...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Fonction ventriculaire › Fonction ventriculaire droite › Female rats are less prone to clinical heart...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Fonction ventriculaire › Pression ventriculaire › Female rats are less prone to clinical heart...