Genetic background of mitral valve prolapse.
familiar form
genetics
genome-wide study
mitral valve disease
mitral valve prolapse
sporadic form
syndromic form
Journal
Reviews in cardiovascular medicine
ISSN: 1530-6550
Titre abrégé: Rev Cardiovasc Med
Pays: Singapore
ID NLM: 100960007
Informations de publication
Date de publication:
12 Mar 2022
12 Mar 2022
Historique:
received:
02
12
2021
revised:
09
01
2022
accepted:
25
01
2022
entrez:
29
3
2022
pubmed:
30
3
2022
medline:
19
4
2022
Statut:
ppublish
Résumé
Mitral valve prolapse (MVP) has a prevalence of 2-3% among the population. It involves a heterogeneous group of patients with different expressions and according to the phenotype can be further divided into fibroelastic deficiency, which is mainly considered as a degeneration due to aging, and myxomatous disease, frequently associated with familiar clusters. Thus, MVP can be present in syndromic, when part of a well-defined syndrome, and non-syndromic forms. The latter occurs more often. To the second belong both familiar and isolated or sporadic forms. On one hand, among familial forms, although X-linked transmission related to
Identifiants
pubmed: 35345263
pii: S1530-6550(22)00420-3
doi: 10.31083/j.rcm2303096
doi:
Substances chimiques
Adaptor Proteins, Signal Transducing
0
DZIP1 protein, human
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
96Informations de copyright
© 2022 The Author(s). Published by IMR Press.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.