Extreme duration exercise affects old and younger men differently.
aerobic fitness
aging
cycling
endurance exercise
energy metabolism
fat oxidation
muscle biopsy
Journal
Acta physiologica (Oxford, England)
ISSN: 1748-1716
Titre abrégé: Acta Physiol (Oxf)
Pays: England
ID NLM: 101262545
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
revised:
23
03
2022
received:
03
11
2021
accepted:
24
03
2022
pubmed:
30
3
2022
medline:
22
6
2022
entrez:
29
3
2022
Statut:
ppublish
Résumé
Extreme endurance exercise provides a valuable research model for understanding the adaptive metabolic response of older and younger individuals to intense physical activity. Here, we compare a wide range of metabolic and physiologic parameters in two cohorts of seven trained men, age 30 ± 5 years or age 65 ± 6 years, before and after the participants travelled ≈3000 km by bicycle over 15 days. Over the 15-day exercise intervention, participants lost 2-3 kg fat mass with no significant change in body weight. V̇O In summary, these data suggest that older but not younger individuals experience a negative adaptive response affecting cardiovascular function in response to extreme endurance exercise, while a positive response to the same exercise intervention is observed in peripheral tissues in younger and older men. The results also suggest that the adaptive thresholds differ in younger and old men, and this difference primarily affects central cardiovascular functions in older men after extreme endurance exercise.
Identifiants
pubmed: 35347845
doi: 10.1111/apha.13816
pmc: PMC9287057
doi:
Substances chimiques
Triglycerides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13816Informations de copyright
© 2022 The Authors. Acta Physiologica published by John Wiley & Sons Ltd on behalf of Scandinavian Physiological Society.
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