Short communication: Leucine, but not muscle contractions, stimulates protein synthesis in isolated EDL muscles from golden geckos.
Ectotherm
Isometric contraction
Nutrient availability
Protein metabolism
Resistance exercise
Skeletal muscle
Journal
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
ISSN: 1531-4332
Titre abrégé: Comp Biochem Physiol A Mol Integr Physiol
Pays: United States
ID NLM: 9806096
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
received:
03
02
2022
revised:
23
03
2022
accepted:
24
03
2022
pubmed:
31
3
2022
medline:
20
4
2022
entrez:
30
3
2022
Statut:
ppublish
Résumé
Resistance exercise and protein ingestion stimulate muscle protein synthesis in mammals and the combination of both stimuli exert an additive effect. However, mechanisms regulating muscle mass may be different in ectothermic vertebrates because these animals are adapted to low energy consumption, short bouts of physical activity, and prolonged periods of inactivity. Here, we investigated the effects of administration of leucine and simulated resistance exercise induced by electrical stimulation (ES) on protein synthesis rate in isolated extensor digitorum longus muscle from golden geckos (Gekko badenii). Muscles were placed in Krebs-Ringer buffer equilibrated with O
Identifiants
pubmed: 35351650
pii: S1095-6433(22)00064-2
doi: 10.1016/j.cbpa.2022.111206
pii:
doi:
Substances chimiques
Muscle Proteins
0
Leucine
GMW67QNF9C
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
111206Informations de copyright
Copyright © 2022. Published by Elsevier Inc.