Nomogram for Predicting In-Hospital Mortality in Patients with Acute ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock after Primary Percutaneous Coronary Intervention.


Journal

Journal of interventional cardiology
ISSN: 1540-8183
Titre abrégé: J Interv Cardiol
Pays: United States
ID NLM: 8907826

Informations de publication

Date de publication:
2022
Historique:
received: 17 11 2021
accepted: 10 02 2022
entrez: 31 3 2022
pubmed: 1 4 2022
medline: 2 4 2022
Statut: epublish

Résumé

Mortality after percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) patients with cardiogenic shock (CS) remains high. However, the real-world risk factors for mortality in these patients are poorly defined. The aim of this study is to establish a clinical prognostic nomogram for predicting in-hospital mortality after primary PCI in STEMI patients with CS. This retrospective, multicenter, observational study included STEMI patients with CS who underwent PCI at 39 hospitals in Hebei Province from January 2018 to December 2019. A multivariate logistic regression model was used to identify the factors associated with in-hospital mortality. These factors were then incorporated into a nomogram and its performance was evaluated by discrimination, calibration, and clinical utility. This study included 274 patients, among whom 179 died in hospital. Sex, random blood glucose on admission, ejection fraction after PCI, no-reflow, and intra-aortic balloon pump (IABP) were independently associated with in-hospital mortality (all We established and validated a nomogram that provided individual prediction of in-hospital mortality for STEMI patients with CS after PCI in a Chinese population.

Sections du résumé

Background UNASSIGNED
Mortality after percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) patients with cardiogenic shock (CS) remains high. However, the real-world risk factors for mortality in these patients are poorly defined.
Objective UNASSIGNED
The aim of this study is to establish a clinical prognostic nomogram for predicting in-hospital mortality after primary PCI in STEMI patients with CS.
Methods UNASSIGNED
This retrospective, multicenter, observational study included STEMI patients with CS who underwent PCI at 39 hospitals in Hebei Province from January 2018 to December 2019. A multivariate logistic regression model was used to identify the factors associated with in-hospital mortality. These factors were then incorporated into a nomogram and its performance was evaluated by discrimination, calibration, and clinical utility.
Results UNASSIGNED
This study included 274 patients, among whom 179 died in hospital. Sex, random blood glucose on admission, ejection fraction after PCI, no-reflow, and intra-aortic balloon pump (IABP) were independently associated with in-hospital mortality (all
Conclusion UNASSIGNED
We established and validated a nomogram that provided individual prediction of in-hospital mortality for STEMI patients with CS after PCI in a Chinese population.

Identifiants

pubmed: 35356419
doi: 10.1155/2022/8994106
pmc: PMC8934239
doi:

Types de publication

Journal Article Multicenter Study Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

8994106

Informations de copyright

Copyright © 2022 Yudan Wang et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

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Auteurs

Yudan Wang (Y)

School of Graduate, Hebei Medical University, Shijiazhuang, Hebei Province, China.
Department of Cardiology Center, Hebei General Hospital, Shijiazhuang, Hebei Province, China.

Litian Liu (L)

Department of Cardiology Center, Hebei General Hospital, Shijiazhuang, Hebei Province, China.

Xinning Li (X)

Department of Cardiology Center, Hebei General Hospital, Shijiazhuang, Hebei Province, China.

Yi Dang (Y)

Department of Cardiology Center, Hebei General Hospital, Shijiazhuang, Hebei Province, China.

Yingxiao Li (Y)

Department of Cardiology Center, Hebei General Hospital, Shijiazhuang, Hebei Province, China.

Jiaqi Wang (J)

School of Graduate, Hebei North University, Zhangjiakou, Hebei Province, China.

Xiaoyong Qi (X)

School of Graduate, Hebei Medical University, Shijiazhuang, Hebei Province, China.
Department of Cardiology Center, Hebei General Hospital, Shijiazhuang, Hebei Province, China.

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