Nuclear Aurora kinase A switches m
Journal
Signal transduction and targeted therapy
ISSN: 2059-3635
Titre abrégé: Signal Transduct Target Ther
Pays: England
ID NLM: 101676423
Informations de publication
Date de publication:
01 04 2022
01 04 2022
Historique:
received:
04
08
2021
accepted:
25
01
2022
revised:
17
01
2022
entrez:
1
4
2022
pubmed:
2
4
2022
medline:
5
4
2022
Statut:
epublish
Résumé
Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression, yet how this process is regulated by oncogenic signal remains largely unknown. Here, we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m
Identifiants
pubmed: 35361747
doi: 10.1038/s41392-022-00905-3
pii: 10.1038/s41392-022-00905-3
pmc: PMC8971511
doi:
Substances chimiques
Nerve Tissue Proteins
0
RNA Splicing Factors
0
RNA-Binding Proteins
0
Aurora Kinase A
EC 2.7.11.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
97Informations de copyright
© 2022. The Author(s).
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