Decentralized Brain Age Estimation Using MRI Data.


Journal

Neuroinformatics
ISSN: 1559-0089
Titre abrégé: Neuroinformatics
Pays: United States
ID NLM: 101142069

Informations de publication

Date de publication:
10 2022
Historique:
accepted: 27 01 2022
pubmed: 6 4 2022
medline: 26 10 2022
entrez: 5 4 2022
Statut: ppublish

Résumé

Recent studies have demonstrated that neuroimaging data can be used to estimate biological brain age, as it captures information about the neuroanatomical and functional changes the brain undergoes during development and the aging process. However, researchers often have limited access to neuroimaging data because of its challenging and expensive acquisition process, thereby limiting the effectiveness of the predictive model. Decentralized models provide a way to build more accurate and generalizable prediction models, bypassing the traditional data-sharing methodology. In this work, we propose a decentralized method for biological brain age estimation using support vector regression models and evaluate it on three different feature sets, including both volumetric and voxelwise structural MRI data as well as resting functional MRI data. The results demonstrate that our decentralized brain age regression models can achieve similar performance compared to the models trained with all the data in one location.

Identifiants

pubmed: 35380365
doi: 10.1007/s12021-022-09570-x
pii: 10.1007/s12021-022-09570-x
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

981-990

Subventions

Organisme : NIMH NIH HHS
ID : R01 MH121246
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA049238
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA040487
Pays : United States

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

Sunitha Basodi (S)

Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA. sbasodi1@gsu.edu.

Rajikha Raja (R)

Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA.
Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Bhaskar Ray (B)

Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA.
Department of Computer Science, Georgia State University, Atlanta, GA, USA.

Harshvardhan Gazula (H)

Princeton Neuroscience Institute, Princeton, NJ, USA.

Anand D Sarwate (AD)

Department of Electrical and Computer Engineering, Rutgers University, Piscataway, NJ, USA.

Sergey Plis (S)

Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA.

Jingyu Liu (J)

Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA.
Department of Computer Science, Georgia State University, Atlanta, GA, USA.

Eric Verner (E)

Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA.

Vince D Calhoun (VD)

Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA.
Department of Computer Science, Georgia State University, Atlanta, GA, USA.
Department of Psychology, Georgia State University, Atlanta, GA, USA.

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