Association between dietary intake of branched-chain amino acids and sarcopenia and its components: a cross-sectional study.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
05 04 2022
05 04 2022
Historique:
received:
20
06
2021
accepted:
10
02
2022
entrez:
6
4
2022
pubmed:
7
4
2022
medline:
8
4
2022
Statut:
epublish
Résumé
There is no previous study that investigated the association between dietary intake of total and individual branched-chain amino acids (BCAAs) and odds of sarcopenia. The present study aimed to examine the association between dietary intake of BCAAs and sarcopenia and its components among Iranian adults. The data for this cross-sectional study was collected in 2011 among 300 older people (150 men and 150 female) with aged ≥ 55 years. We used a Block-format 117-item food frequency questionnaire (FFQ) to evaluate usual dietary intakes. BCAAs intake was calculated by summing up the amount of valine, leucine and isoleucine intake from all food items in the FFQ. The European Sarcopenia Working Group (EWGSOP) definition was used to determine sarcopenia and its components. Mean age of study participants was 66.8 years and 51% were female. Average intake of BCAAs was 12.8 ± 5.1 g/day. Prevalence of sarcopenia and its components was not significantly different across tertile categories of total and individual BCAAs intake. We found no significant association between total BCAAs intake and odds of sarcopenia (OR for comparison of extreme tertiles 0.48, 95% CI 0.19-1.19, P-trend = 0.10) and its components (For muscle mass 0.83, 95% CI 0.39-1.77, P-trend = 0.63; for hand grip strength 0.81, 95% CI 0.37-1.75, P-trend: 0.59; for gait speed 1.22, 95% CI 0.58-2.57, P-trend = 0.56). After adjusting for potential confounders, this non-significant relationship did not alter. In addition, we did not find any significant association between individual BCAAs intake and odds of sarcopenia or its components. We found no significant association between dietary intakes of BCAAs and sarcopenia in crude model (OR 0.60; 95% CI 0.29-1.26). After controlling for several potential confounders, the result remained insignificant (OR 0.48; 95% CI 0.19-1.19). In this cross-sectional study, no significant association was observed between dietary intakes of total and individual BCAAs and odds of sarcopenia and its components.
Identifiants
pubmed: 35383191
doi: 10.1038/s41598-022-07605-6
pii: 10.1038/s41598-022-07605-6
pmc: PMC8983668
doi:
Substances chimiques
Amino Acids, Branched-Chain
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
5666Informations de copyright
© 2022. The Author(s).
Références
Age Ageing. 2011 Jul;40(4):423-9
pubmed: 21624928
J Nutr Health Aging. 2019;23(1):27-34
pubmed: 30569065
Endocrinology. 2009 Sep;150(9):4084-93
pubmed: 19470704
J Endocrinol. 2016 May;229(2):R67-81
pubmed: 26931135
J Am Med Dir Assoc. 2014 Feb;15(2):95-101
pubmed: 24461239
J Diabetes. 2018 May;10(5):350-352
pubmed: 29369529
Br J Nutr. 2018 Aug;120(4):445-453
pubmed: 29909813
J Diabetes Metab Disord. 2017 May 16;16:21
pubmed: 28523252
Hum Genet. 2012 Jan;131(1):1-31
pubmed: 21706341
Br J Nutr. 2017 Jun;117(11):1523-1530
pubmed: 28721839
Muscle Nerve. 2000 Sep;23(9):1393-401
pubmed: 10951442
J Diabetes Metab Disord. 2012 Nov 21;11(1):23
pubmed: 23497567
J Am Geriatr Soc. 2002 May;50(5):889-96
pubmed: 12028177
Worldviews Evid Based Nurs. 2016 Apr;13(2):153-62
pubmed: 26844538
Int J Epidemiol. 2016 Oct;45(5):1482-1492
pubmed: 27413102
Age Ageing. 2014 Nov;43(6):748-59
pubmed: 25241753
Nutr Clin Pract. 2013 Dec;28(6):684-90
pubmed: 24163319
J Epidemiol. 2016;26(1):36-44
pubmed: 26277881
J Clin Med Res. 2015 Dec;7(12):926-31
pubmed: 26566405
Drugs Aging. 2002;19(11):865-77
pubmed: 12428995
Nutrients. 2018 Nov 06;10(11):
pubmed: 30404172
J Am Geriatr Soc. 2004 Jan;52(1):80-5
pubmed: 14687319
Nutrition. 2015 Jan;31(1):97-104
pubmed: 25441592
PLoS One. 2015 Aug 14;10(8):e0135437
pubmed: 26274920
J Nutr. 2000 Oct;130(10):2413-9
pubmed: 11015466
Clin Geriatr Med. 2011 Aug;27(3):449-70
pubmed: 21824557
Am J Clin Nutr. 1990 Aug;52(2):214-8
pubmed: 2375286
Clin Nutr. 2018 Aug;37(4):1121-1132
pubmed: 28927897
Age Ageing. 2010 Jul;39(4):412-23
pubmed: 20392703
Med Sci Sports Exerc. 2011 Dec;43(12):2249-58
pubmed: 21606874
Am J Clin Nutr. 2016 Dec;104(6):1594-1606
pubmed: 27935521
Geriatr Gerontol Int. 2014 Feb;14 Suppl 1:1-7
pubmed: 24450555
PLoS One. 2017 Sep 21;12(9):e0185206
pubmed: 28934309
Arch Gerontol Geriatr. 2016 Sep-Oct;66:18-22
pubmed: 27176487
Calcif Tissue Int. 2013 Aug;93(2):101-20
pubmed: 23828275
Am J Clin Nutr. 2007 Mar;85(3):910-8
pubmed: 17344515
Public Health Nutr. 2010 May;13(5):654-62
pubmed: 19807937
Clin Nutr. 2020 Jul;39(7):2080-2091
pubmed: 31672329
Am J Epidemiol. 1985 Jul;122(1):51-65
pubmed: 4014201
J Nutr. 2006 Jan;136(1 Suppl):227S-31S
pubmed: 16365087
J Am Med Dir Assoc. 2016 Aug 1;17(8):675-7
pubmed: 27470918
J Clin Endocrinol Metab. 2004 Sep;89(9):4351-8
pubmed: 15356032
J Am Med Dir Assoc. 2010 Jul;11(6):391-6
pubmed: 20627179
Am J Clin Nutr. 2003 Aug;78(2):250-8
pubmed: 12885705
Arch Public Health. 2014 Dec 18;72(1):45
pubmed: 25810912
Nutr Rev. 2011 Sep;69(9):550-7
pubmed: 21884134
J Appl Physiol (1985). 1997 Jul;83(1):229-39
pubmed: 9216968
J Nutr. 2008 Aug;138(8):1469-75
pubmed: 18641193
Br J Nutr. 2009 Aug;102(4):632-41
pubmed: 19203416
J Clin Densitom. 2015 Oct-Dec;18(4):461-6
pubmed: 26073423
J Physiol. 2018 Feb 15;596(4):623-645
pubmed: 29266268
Aging (Albany NY). 2020 Jul 26;12(14):15091-15103
pubmed: 32712600
J Nutr Health Aging. 2015 Apr;19(4):437-46
pubmed: 25809808