Separating Neural Oscillations from Aperiodic 1/f Activity: Challenges and Recommendations.


Journal

Neuroinformatics
ISSN: 1559-0089
Titre abrégé: Neuroinformatics
Pays: United States
ID NLM: 101142069

Informations de publication

Date de publication:
10 2022
Historique:
accepted: 25 02 2022
pubmed: 8 4 2022
medline: 26 10 2022
entrez: 7 4 2022
Statut: ppublish

Résumé

Electrophysiological power spectra typically consist of two components: An aperiodic part usually following an 1/f power law [Formula: see text] and periodic components appearing as spectral peaks. While the investigation of the periodic parts, commonly referred to as neural oscillations, has received considerable attention, the study of the aperiodic part has only recently gained more interest. The periodic part is usually quantified by center frequencies, powers, and bandwidths, while the aperiodic part is parameterized by the y-intercept and the 1/f exponent [Formula: see text]. For investigation of either part, however, it is essential to separate the two components. In this article, we scrutinize two frequently used methods, FOOOF (Fitting Oscillations & One-Over-F) and IRASA (Irregular Resampling Auto-Spectral Analysis), that are commonly used to separate the periodic from the aperiodic component. We evaluate these methods using diverse spectra obtained with electroencephalography (EEG), magnetoencephalography (MEG), and local field potential (LFP) recordings relating to three independent research datasets. Each method and each dataset poses distinct challenges for the extraction of both spectral parts. The specific spectral features hindering the periodic and aperiodic separation are highlighted by simulations of power spectra emphasizing these features. Through comparison with the simulation parameters defined a priori, the parameterization error of each method is quantified. Based on the real and simulated power spectra, we evaluate the advantages of both methods, discuss common challenges, note which spectral features impede the separation, assess the computational costs, and propose recommendations on how to use them.

Identifiants

pubmed: 35389160
doi: 10.1007/s12021-022-09581-8
pii: 10.1007/s12021-022-09581-8
pmc: PMC9588478
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

991-1012

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom

Informations de copyright

© 2022. The Author(s).

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Auteurs

Moritz Gerster (M)

Research Group Neural Interactions and Dynamics, Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. mogerster@cbs.mpg.de.
Neurophysics Group, Department of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. mogerster@cbs.mpg.de.
Bernstein Center for Computational Neuroscience, Berlin, Germany. mogerster@cbs.mpg.de.

Gunnar Waterstraat (G)

Neurophysics Group, Department of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Vladimir Litvak (V)

Wellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, London, UK.

Klaus Lehnertz (K)

Department of Epileptology, University of Bonn Medical Centre, Bonn, Germany.
Helmholtz Institute for Radiation and Nuclear Physics, University of Bonn, Bonn, Germany.
Interdisciplinary Center for Complex Systems, University of Bonn, Bonn, Germany.

Alfons Schnitzler (A)

Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.

Esther Florin (E)

Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.

Gabriel Curio (G)

Neurophysics Group, Department of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Bernstein Center for Computational Neuroscience, Berlin, Germany.

Vadim Nikulin (V)

Research Group Neural Interactions and Dynamics, Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Neurophysics Group, Department of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Bernstein Center for Computational Neuroscience, Berlin, Germany.

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