Assessing the aneurysm occlusion efficacy of a shear-thinning biomaterial in a 3D-printed model.

Aneurysm / therapy Arteries Biocompatible Materials / pharmacology Humans Printing, Three-Dimensional Stents Treatment Outcome
Catheters Hydrogels Minimally invasive Pseudoaneurysms Shear-thinning biomaterials Silicate nanoplatelets Visceral artery aneurysms

Journal

Journal of the mechanical behavior of biomedical materials
ISSN: 1878-0180
Titre abrégé: J Mech Behav Biomed Mater
Pays: Netherlands
ID NLM: 101322406

Informations de publication

Date de publication:
06 2022
Historique:
received: 11 07 2021
revised: 13 02 2022
accepted: 27 02 2022
pubmed: 10 4 2022
medline: 22 4 2022
entrez: 9 4 2022
Statut: ppublish

Résumé

Metallic coil embolization is a common method for the endovascular treatment of visceral artery aneurysms (VAA) and visceral artery pseudoaneurysms (VAPA); however, this treatment is suboptimal due to the high cost of coils, incomplete volume occlusion, poor reendothelialization, aneurysm puncture, and coil migration. Several alternative treatment strategies are available, including stent flow diverters, glue embolics, gelfoam slurries, and vascular mesh plugs-each of which have their own disadvantages. Here, we investigated the in vitro capability of a shear-thinning biomaterial (STB), a nanocomposite hydrogel composed of gelatin and silicate nanoplatelets, for the minimally-invasive occlusion of simple necked aneurysm models. We demonstrated the injectability of STB through various clinical catheters, engineered an in vitro testing apparatus to independently manipulate aneurysm neck diameter, fluid flow rate, and flow waveform, and tested the stability of STB within the models under various conditions. Our experiments show that STB is able to withstand at least 1.89 Pa of wall shear stress, as estimated by computational fluid dynamics. STB is also able to withstand up to 10 mL s

Identifiants

DOI: 10.1016/j.jmbbm.2022.105156 PMID: 35397405 PMC: PMC9060636
pubmed: 35397405
pii: S1751-6161(22)00078-9
doi: 10.1016/j.jmbbm.2022.105156
pmc: PMC9060636
mid: NIHMS1795351
pii:
doi:

Substances chimiques

Biocompatible Materials 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

105156

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL140951
Pays : United States
Organisme : CIHR
Pays : Canada

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Références

Am J Cardiol. 1997 Aug 1;80(3):323-30
pubmed: 9264426
AJNR Am J Neuroradiol. 1999 Mar;20(3):401-10
pubmed: 10219404
Neurosurgery. 2006 Jan;58(1):51-9; discussion 51-9
pubmed: 16385329
J Vasc Surg. 2006 Oct;44(4):718-24
pubmed: 17011997
J Med Device. 2009 Dec;3(4):41005
pubmed: 20354576
Cardiovasc Eng Technol. 2021 Apr;12(2):200-214
pubmed: 33263929
J Neurointerv Surg. 2010 Jun;2(2):163-7
pubmed: 21990601
Rofo. 2017 Jul;189(7):632-639
pubmed: 28511264
Eur J Vasc Endovasc Surg. 2020 Nov;60(5):773-779
pubmed: 32792290
Clin Endosc. 2021 Nov;54(6):920-923
pubmed: 33430578
Macromol Biosci. 2020 Mar;20(3):e1900234
pubmed: 31912982
Ultrasonography. 2015 Apr;34(2):98-108
pubmed: 25754367
Med Eng Phys. 2018 Sep;59:21-29
pubmed: 30077485
Int J Angiol. 2019 Mar;28(1):11-16
pubmed: 30880885
J Neurosurg. 1999 Aug;91(2):284-93
pubmed: 10433317
Biomater Sci. 2018 Jul 24;6(8):2073-2083
pubmed: 29944151
Ann Biomed Eng. 2020 Oct;48(10):2484-2493
pubmed: 32524379
Stroke. 2011 Mar;42(3):745-53
pubmed: 21233477
Acta Cir Bras. 2009 Jan-Feb;24(1):43-7
pubmed: 19169541
Int J Med Robot. 2013 Jun;9(2):213-22
pubmed: 23483681
Biomater Sci. 2021 Jun 15;9(12):4343-4355
pubmed: 33724267
World J Radiol. 2015 Jul 28;7(7):143-8
pubmed: 26217453
J Med Biol Eng. 2015;35(3):293-304
pubmed: 26167140
J Clin Neurosci. 2019 Mar;61:153-159
pubmed: 30470652
Sci Rep. 2017 Jul 13;7(1):5331
pubmed: 28706287
Eur Radiol. 2015 Jul;25(7):2004-14
pubmed: 25693662
Cardiovasc Intervent Radiol. 2006 Nov-Dec;29(6):1125-8
pubmed: 16625409
PLoS One. 2015 Sep 23;10(9):e0138648
pubmed: 26398847
J Vasc Interv Radiol. 2019 Nov;30(11):1840-1844.e1
pubmed: 31587948
J Neurointerv Surg. 2019 Oct;11(10):999-1003
pubmed: 30979845
ACS Nano. 2014 Oct 28;8(10):9833-42
pubmed: 25221894
Sci Transl Med. 2016 Nov 16;8(365):365ra156
pubmed: 27856795
EJVES Short Rep. 2018 May 30;39:33-36
pubmed: 29988858
Radiographics. 2005 Oct;25 Suppl 1:S173-89
pubmed: 16227490
J Neurointerv Surg. 2018 Mar;10(3):252-257
pubmed: 28377443
Asian Cardiovasc Thorac Ann. 2018 Feb;26(2):133-138
pubmed: 29363319
Korean J Radiol. 2016 May-Jun;17(3):351-63
pubmed: 27134524
Hepatology. 1993 May;17(5):788-93
pubmed: 8491446
Asian J Neurosurg. 2012 Jul;7(3):109-15
pubmed: 23293665
Front Surg. 2016 Jul 25;3:43
pubmed: 27504449
Sci Rep. 2021 Jan 12;11(1):700
pubmed: 33436829
J Cereb Blood Flow Metab. 2020 May;40(5):922-938
pubmed: 32126875
J Vasc Interv Neurol. 2015 Jul;8(3):37-41
pubmed: 26301030
Diagn Interv Imaging. 2015 Jul-Aug;96(7-8):797-806
pubmed: 26054246
AJNR Am J Neuroradiol. 2013 Jul;34(7):1387-94
pubmed: 23306008
Am J Physiol. 1998 Feb;274(2):H500-5
pubmed: 9486253
AJR Am J Roentgenol. 2017 Aug;209(2):243-247
pubmed: 28731812
J Mater Sci Mater Med. 2020 Mar 14;31(3):34
pubmed: 32172490

Auteurs

Grant Schroeder (G)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Masoud Edalati (M)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA; Department of Mechanical Engineering Rowan University, Rowan Hall 201 Mullica Hill Rd. Glassboro, NJ, 08028, USA.

Gregory Tom (G)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA.

Nicole Kuntjoro (N)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA.

Mark Gutin (M)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA; Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

Melvin Gurian (M)

Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

Edoardo Cuniberto (E)

Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

Elisabeth Hirth (E)

Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

Alessia Martiri (A)

Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

Maria Teresa Sposato (MT)

Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

Selda Aminzadeh (S)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA.

James Eichenbaum (J)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA.

Parvin Alizadeh (P)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA; Department of Materials Science & Engineering, Faculty of Engineering & Technology, Tarbiat Modares University, Tehran, Iran.

Avijit Baidya (A)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA.

Reihaneh Haghniaz (R)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA; Terasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.

Rohollah Nasiri (R)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA.

Naoki Kaneko (N)

Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Ave, Los Angeles, CA, 90095, USA.

Abraham Mansouri (A)

Department of Mechanical Engineering, Higher College of Technology, Dubai, 15825, United Arab Emirates.

Ali Khademhosseini (A)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA; Terasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA. Electronic address: khademh@terasaki.org.

Amir Sheikhi (A)

Department of Bioengineering, University of California, Los Angeles, 410 Westwood Plaza, Los Angeles, CA, 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, 570 Westwood Plaza, Los Angeles, CA, 90095, USA; Department of Chemical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA; Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA. Electronic address: sheikhi@psu.edu.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Anévrysme › Assessing the aneurysm occlusion efficacy of a...
questionsmedicales.fr › Système cardiovasculaire › Vaisseaux sanguins › Artères › Assessing the aneurysm occlusion efficacy of a...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Matériaux biocompatibles › Assessing the aneurysm occlusion efficacy of a...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Assessing the aneurysm occlusion efficacy of a...
questionsmedicales.fr › Sciences de l'information › Affichage de données › Infographie › Conception assistée par ordinateur › Impression tridimensionnelle › Assessing the aneurysm occlusion efficacy of a...
questionsmedicales.fr › Équipement et fournitures › Prothèses et implants › Endoprothèses › Assessing the aneurysm occlusion efficacy of a...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Qualité des soins de santé › Mécanismes d'évaluation des soins de santé › Évaluation des résultats et des processus en soins de santé › Évaluation de résultat (soins) › Résultat thérapeutique › Assessing the aneurysm occlusion efficacy of a...