Optimizing Care of Patients With Right Bundle Branch Block Undergoing Transcatheter Aortic Valve Replacement.


Journal

Cardiovascular revascularization medicine : including molecular interventions
ISSN: 1878-0938
Titre abrégé: Cardiovasc Revasc Med
Pays: United States
ID NLM: 101238551

Informations de publication

Date de publication:
09 2022
Historique:
received: 28 12 2021
revised: 07 03 2022
accepted: 22 03 2022
pubmed: 11 4 2022
medline: 17 8 2022
entrez: 10 4 2022
Statut: ppublish

Résumé

To evaluate the use of temporary-permanent pacemaker (TPP) in patients with right bundle branch block (RBBB) undergoing transcatheter aortic valve replacement (TAVR). We also sought to identify key predictors of permanent pacemaker (PPM) within 30 days of TAVR in this population. RBBB is a well-recognized risk factor for PPM post TAVR. TPP provides stable transient pacing and reduces the need for critical care beds. This is a retrospective chart review of 371 patients who underwent TAVR at our institution. All patients with pre-existing RBBB had TPP placed prior to TAVR (n = 37). The primary outcome was the need for critical care beds. Multivariate logistic regression analysis was performed to identify predictors of PPM within 30 days of TAVR. 67 patients required PPM within 30 days of TAVR, and 56 implanted before discharge. 51% (19 out of 37) of TPP group required PPM before discharge compared to 11% (37 out of 334) of No TPP (p < 0.001), yet TPP group spent significantly fewer hours in a critical care bed (19 vs 28 h, p = 0.01). Length of membranous septum (LMS) <8.49 mm was the strongest independent predictor of PPM within 30 days of TAVR (RAUC of 0.80, Sensitivity 0.7 and Specificity 0.8) and 98% of patients with LMS < 7 mm required PPM within 30 days. TPP-TAVR is a well-defined multidisciplinary protocol that reduces the need for critical care beds in patients with pre-existing RBBB referred for TAVR. Additionally, LMS is the strongest predictor of PPM implantation in this population. CONDENSED ABSTRACT (100 WORDS): This study evaluated the use of temporary-permanent pacemakers (TPP) in patients with right bundle branch block (RBBB) undergoing transcatheter aortic valve replacement (TAVR). TPP-TAVR provided stable pacing allowing for early mobilization and reduced the need for critical care beds. Multivariate logistic regression analysis identified length of membranous septum (LMS) <8.49 mm in patients with RBBB as the strongest independent predictor of PPM need within 30 days of TAVR. 98% of patients with RBBB and LMS < 7 mm required PPM at 30 days regardless of other characteristics including valve type and size.

Sections du résumé

OBJECTIVES
To evaluate the use of temporary-permanent pacemaker (TPP) in patients with right bundle branch block (RBBB) undergoing transcatheter aortic valve replacement (TAVR). We also sought to identify key predictors of permanent pacemaker (PPM) within 30 days of TAVR in this population.
BACKGROUND
RBBB is a well-recognized risk factor for PPM post TAVR. TPP provides stable transient pacing and reduces the need for critical care beds.
METHODS
This is a retrospective chart review of 371 patients who underwent TAVR at our institution. All patients with pre-existing RBBB had TPP placed prior to TAVR (n = 37). The primary outcome was the need for critical care beds. Multivariate logistic regression analysis was performed to identify predictors of PPM within 30 days of TAVR.
RESULTS
67 patients required PPM within 30 days of TAVR, and 56 implanted before discharge. 51% (19 out of 37) of TPP group required PPM before discharge compared to 11% (37 out of 334) of No TPP (p < 0.001), yet TPP group spent significantly fewer hours in a critical care bed (19 vs 28 h, p = 0.01). Length of membranous septum (LMS) <8.49 mm was the strongest independent predictor of PPM within 30 days of TAVR (RAUC of 0.80, Sensitivity 0.7 and Specificity 0.8) and 98% of patients with LMS < 7 mm required PPM within 30 days.
CONCLUSION
TPP-TAVR is a well-defined multidisciplinary protocol that reduces the need for critical care beds in patients with pre-existing RBBB referred for TAVR. Additionally, LMS is the strongest predictor of PPM implantation in this population. CONDENSED ABSTRACT (100 WORDS): This study evaluated the use of temporary-permanent pacemakers (TPP) in patients with right bundle branch block (RBBB) undergoing transcatheter aortic valve replacement (TAVR). TPP-TAVR provided stable pacing allowing for early mobilization and reduced the need for critical care beds. Multivariate logistic regression analysis identified length of membranous septum (LMS) <8.49 mm in patients with RBBB as the strongest independent predictor of PPM need within 30 days of TAVR. 98% of patients with RBBB and LMS < 7 mm required PPM at 30 days regardless of other characteristics including valve type and size.

Identifiants

pubmed: 35398009
pii: S1553-8389(22)00154-3
doi: 10.1016/j.carrev.2022.03.018
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

17-25

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Adnan Kassier (A)

Spectrum Health - Michigan State University, Grand Rapids, MI, United States of America; Frederik Meijer Heart & Vascular Institute, Spectrum Health, Grand Rapids, MI, United States of America. Electronic address: adnan.kassier@gmail.com.

Poonam Velagapudi (P)

Division of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, NE, United States of America.

Nabin Manandhar Shrestha (NM)

The DeVos Cardiovascular Research Program, Van Andel Research Institute, Spectrum Health, Grand Rapids, MI, United States of America.

Jennifer Schuitema (J)

The DeVos Cardiovascular Research Program, Van Andel Research Institute, Spectrum Health, Grand Rapids, MI, United States of America.

Andre Gauri (A)

Spectrum Health - Michigan State University, Grand Rapids, MI, United States of America; Frederik Meijer Heart & Vascular Institute, Spectrum Health, Grand Rapids, MI, United States of America.

Jamie Frost (J)

Advanced Radiology Services, Spectrum Health - Michigan State University, Grand Rapids, MI, United States of America.

William Merhi (W)

Spectrum Health - Michigan State University, Grand Rapids, MI, United States of America; Frederik Meijer Heart & Vascular Institute, Spectrum Health, Grand Rapids, MI, United States of America.

Stefan Jovinge (S)

Frederik Meijer Heart & Vascular Institute, Spectrum Health, Grand Rapids, MI, United States of America; The DeVos Cardiovascular Research Program, Van Andel Research Institute, Spectrum Health, Grand Rapids, MI, United States of America.

Nagib Chalfoun (N)

Spectrum Health - Michigan State University, Grand Rapids, MI, United States of America; Frederik Meijer Heart & Vascular Institute, Spectrum Health, Grand Rapids, MI, United States of America.

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