Heterobimetallic complexes containing organometallic acylhydrazone ligands as potential inhibitors of human carbonic anhydrases.
Carbonic anhydrase
Characterization
Inhibitors
Organometallic-acylhydrazones ligands
Ru(II) complexes
Synthesis
Journal
Journal of inorganic biochemistry
ISSN: 1873-3344
Titre abrégé: J Inorg Biochem
Pays: United States
ID NLM: 7905788
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
received:
27
10
2021
revised:
28
03
2022
accepted:
31
03
2022
pubmed:
12
4
2022
medline:
14
5
2022
entrez:
11
4
2022
Statut:
ppublish
Résumé
In the search of new bioorganometallic compounds as potential inhibitors of human (h) carbonic anhydrases (hCAs, EC 4.2.1.1), heterobinuclear ruthenium(II) complexes based on organometallic-acylhydrazones have been obtained. The complexes (1a-b, 2a-b) were prepared by reaction between the corresponding organometallic-acylhydrazone of the general formula [{(η
Identifiants
pubmed: 35405491
pii: S0162-0134(22)00103-9
doi: 10.1016/j.jinorgbio.2022.111814
pii:
doi:
Substances chimiques
Antigens, Neoplasm
0
Carbonic Anhydrase Inhibitors
0
Ligands
0
Carbonic Anhydrases
EC 4.2.1.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
111814Informations de copyright
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