L-Type Ca
Cav1.3 channels
adrenergic regulation
cardiac pacemaker activity
ryanodine receptors
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
25 03 2022
25 03 2022
Historique:
received:
09
11
2021
revised:
18
03
2022
accepted:
23
03
2022
entrez:
12
4
2022
pubmed:
13
4
2022
medline:
14
4
2022
Statut:
epublish
Résumé
Sinoatrial node cells (SANC) automaticity is generated by functional association between the activity of plasmalemmal ion channels and local diastolic intracellular Ca To investigate the role of L-type Ca In dormant SANC, β-adrenergic stimulation with isoproterenol (ISO) induced spontaneous action potentials (AP) and Ca Our study shows a novel role of Ca
Sections du résumé
BACKGROUND
Sinoatrial node cells (SANC) automaticity is generated by functional association between the activity of plasmalemmal ion channels and local diastolic intracellular Ca
METHODS
To investigate the role of L-type Ca
RESULTS
In dormant SANC, β-adrenergic stimulation with isoproterenol (ISO) induced spontaneous action potentials (AP) and Ca
CONCLUSIONS
Our study shows a novel role of Ca
Identifiants
pubmed: 35406677
pii: cells11071114
doi: 10.3390/cells11071114
pmc: PMC8997967
pii:
doi:
Substances chimiques
Adrenergic Agents
0
Ryanodine Receptor Calcium Release Channel
0
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
Acta Pharmacol Sin. 2016 Jan;37(1):82-97
pubmed: 26725737
Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12189-94
pubmed: 19570998
Basic Res Cardiol. 2010 Jan;105(1):73-87
pubmed: 19639379
Cardiovasc Res. 2007 Feb 1;73(3):531-8
pubmed: 17188667
EMBO J. 2007 Oct 31;26(21):4423-32
pubmed: 17914461
Front Physiol. 2015 Feb 02;6:19
pubmed: 25698974
Cardiovasc Res. 2016 Mar 1;109(3):451-61
pubmed: 26786159
Nat Commun. 2014 Aug 21;5:4664
pubmed: 25144323
Am J Physiol. 1999 Mar;276(3):H1064-77
pubmed: 10070093
Circ Res. 2006 Mar 3;98(4):505-14
pubmed: 16424365
Circ Arrhythm Electrophysiol. 2010 Oct;3(5):542-52
pubmed: 20693575
J Mol Cell Cardiol. 1986 Oct;18(10):1015-31
pubmed: 3783721
Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H2010-23
pubmed: 20228256
Sci Rep. 2020 Nov 3;10(1):18906
pubmed: 33144668
Cardiovasc Res. 2000 Sep;47(4):658-87
pubmed: 10974216
Annu Rev Physiol. 1993;55:455-72
pubmed: 7682045
J Biol Chem. 2001 Jun 22;276(25):22100-6
pubmed: 11285265
J Physiol. 2004 Sep 15;559(Pt 3):835-48
pubmed: 15254155
Heart Rhythm. 2013 Nov;10(11):1683-9
pubmed: 23954346
Sci Rep. 2020 Jun 17;10(1):9835
pubmed: 32555258
Am J Physiol Heart Circ Physiol. 2004 May;286(5):H1757-66
pubmed: 14693686
Biophys J. 2018 Mar 13;114(5):1176-1189
pubmed: 29539403
Crit Care Nurs Clin North Am. 2016 Sep;28(3):269-79
pubmed: 27484656
Cells. 2021 Aug 18;10(8):
pubmed: 34440893
J Physiol. 2005 Jan 1;562(Pt 1):223-34
pubmed: 15498808
Sci Rep. 2017 Aug 11;7(1):7869
pubmed: 28801600
Elife. 2018 Jun 20;7:
pubmed: 29923826
Circ Res. 2008 Apr 11;102(7):761-9
pubmed: 18276917
Front Physiol. 2021 Apr 09;12:596832
pubmed: 33897445
Prog Biophys Mol Biol. 2006 Jan-Apr;90(1-3):38-63
pubmed: 15979127
Int J Mol Sci. 2021 Aug 05;22(16):
pubmed: 34445119
Circ Res. 2000 Oct 27;87(9):760-7
pubmed: 11055979
Cardiovasc Res. 2001 Oct;52(1):51-64
pubmed: 11557233
Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5543-8
pubmed: 12700358
J Gen Physiol. 2013 Aug;142(2):113-26
pubmed: 23858001
Nature. 1991 May 9;351(6322):145-7
pubmed: 1709448
Circ Res. 2010 Feb 19;106(3):434-46
pubmed: 20167941
Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1705-10
pubmed: 21220308
Circ Res. 2010 Sep 17;107(6):767-75
pubmed: 20651285
Circ Res. 2010 Mar 5;106(4):659-73
pubmed: 20203315
Cell Calcium. 2018 Sep;74:168-179
pubmed: 30092494
JACC Clin Electrophysiol. 2020 Aug;6(8):907-931
pubmed: 32819526
J Clin Invest. 2004 May;113(10):1430-9
pubmed: 15146240
Front Physiol. 2021 May 27;12:669029
pubmed: 34122140
Sci Signal. 2018 Jun 12;11(534):
pubmed: 29895616
PeerJ. 2019 Mar 29;7:e6652
pubmed: 30956900
Nat Neurosci. 2011 Aug 07;14(9):1109-11
pubmed: 21822269
Nat Commun. 2020 Nov 3;11(1):5555
pubmed: 33144559
Circ Res. 2007 Jun 8;100(11):1605-14
pubmed: 17478725
Circ Res. 1995 Apr;76(4):607-15
pubmed: 7895335
Cardiovasc Res. 2001 Oct;52(1):40-50
pubmed: 11557232
Physiol Rev. 2008 Jul;88(3):919-82
pubmed: 18626064
J Electrocardiol. 2011 Nov-Dec;44(6):626-34
pubmed: 21937057
Front Physiol. 2015 Feb 13;6:28
pubmed: 25741284
J Physiol. 2012 Dec 15;590(24):6327-42
pubmed: 23045342
Circ Res. 2004 Apr 2;94(6):802-9
pubmed: 14963011