Highly efficient, processive and multifunctional recombinant endoglucanase RfGH5_4 from Ruminococcus flavefaciens FD-1 v3 for recycling lignocellulosic plant biomasses.


Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
01 Jun 2022
Historique:
received: 08 02 2022
revised: 18 03 2022
accepted: 08 04 2022
pubmed: 15 4 2022
medline: 18 5 2022
entrez: 14 4 2022
Statut: ppublish

Résumé

Gene encoding endoglucanase, RfGH5_4 from R. flavefaciens FD-1 v3 was cloned, expressed in Escherichia coli BL21(DE3) cells and purified. RfGH5_4 showed molecular size 41 kDa and maximum activity at pH 5.5 and 55 °C. It was stable between pH 5.0-8.0, retaining 85% activity and between 5 °C-45 °C, retaining 75% activity, after 60 min. RfGH5_4 displayed maximum activity (U/mg) against barley β-D-glucan (665) followed by carboxymethyl cellulose (450), xyloglucan (343), konjac glucomannan (285), phosphoric acid swollen cellulose (86), beechwood xylan (21.7) and carob galactomannan (16), thereby displaying the multi-functionality. Catalytic efficiency (mL.mg

Identifiants

pubmed: 35421411
pii: S0141-8130(22)00763-2
doi: 10.1016/j.ijbiomac.2022.04.059
pii:
doi:

Substances chimiques

lignocellulose 11132-73-3
Tegafur 1548R74NSZ
FD 1 62987-05-7
Cellulose 9004-34-6
Lignin 9005-53-2
Cellulase EC 3.2.1.4
Carboxymethylcellulose Sodium K679OBS311

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

801-813

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Auteurs

Parmeshwar Vitthal Gavande (PV)

Department of Biosciences and Bioengineering, Carbohydrate Enzyme Biotechnology Laboratory, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.

Priyanka Nath (P)

Department of Biosciences and Bioengineering, Carbohydrate Enzyme Biotechnology Laboratory, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.

Krishan Kumar (K)

Department of Biosciences and Bioengineering, Carbohydrate Enzyme Biotechnology Laboratory, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.

Nazneen Ahmed (N)

Department of Biosciences and Bioengineering, Carbohydrate Enzyme Biotechnology Laboratory, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.

Carlos M G A Fontes (CMGA)

CIISA - Faculdade de Medicina Veterinária, Universidade de Lisboa, Avenida da Universidade Técnica, 1300-477 Lisbon, Portugal; NZYTech - Genes & Enzymes, Estrada do Paço do Lumiar, Campus do Lumiar, Edifício, Lisbon, Portugal.

Arun Goyal (A)

Department of Biosciences and Bioengineering, Carbohydrate Enzyme Biotechnology Laboratory, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India. Electronic address: arungoyl@iitg.ac.in.

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Classifications MeSH