Unicuspid Aortic Valve in Patients Undergoing the Ross Procedure.


Journal

The Annals of thoracic surgery
ISSN: 1552-6259
Titre abrégé: Ann Thorac Surg
Pays: Netherlands
ID NLM: 15030100R

Informations de publication

Date de publication:
03 2023
Historique:
received: 08 12 2021
revised: 28 02 2022
accepted: 22 03 2022
pubmed: 18 4 2022
medline: 25 2 2023
entrez: 17 4 2022
Statut: ppublish

Résumé

The prevalence and outcomes of the unicuspid aortic valve (UAV) in patients undergoing the Ross procedure have been strongly underreported in the current literature. We sought to evaluate this in comparison with bicuspid (BAV) and tricuspid valve (TAV) in our Ross cohort. This was a retrospective observational study of patients undergoing the Ross procedure at 2 dedicated centers between 2009 and 2020. Primary end points were the risks of midterm autograft reoperation and the onset of at least moderate aortic regurgitation during follow-up. The secondary end point was to compare the perioperative outcomes between the groups. Included in the analysis were 286 patients, of those 39% with UAV, 52% with BAV, and 9% with TAV. UAV patients were operated on at the youngest age (P < .001) and more often for a combined hemodynamic aortic valve pathology (P = .02). They had the largest aortic root dimensions: annulus (P = .01), Valsalva sinuses (P = .11), sinotubular junction (P = .001), and ascending aorta (P < .0001). The risks of reoperation (P = .86) and the onset of aortic regurgitation (P = .75) were comparable among the groups over the follow-up of 4.1 years. There was no difference in perioperative outcomes. UAV is a separate unit characterized by a distinct hemodynamic pathology and generated aortopathy. It is not associated with a higher risk of reoperation or new onset of aortic regurgitation after the Ross procedure in the midterm postoperatively. At the current state, UAV remains acceptable for the Ross procedure.

Sections du résumé

BACKGROUND
The prevalence and outcomes of the unicuspid aortic valve (UAV) in patients undergoing the Ross procedure have been strongly underreported in the current literature. We sought to evaluate this in comparison with bicuspid (BAV) and tricuspid valve (TAV) in our Ross cohort.
METHODS
This was a retrospective observational study of patients undergoing the Ross procedure at 2 dedicated centers between 2009 and 2020. Primary end points were the risks of midterm autograft reoperation and the onset of at least moderate aortic regurgitation during follow-up. The secondary end point was to compare the perioperative outcomes between the groups.
RESULTS
Included in the analysis were 286 patients, of those 39% with UAV, 52% with BAV, and 9% with TAV. UAV patients were operated on at the youngest age (P < .001) and more often for a combined hemodynamic aortic valve pathology (P = .02). They had the largest aortic root dimensions: annulus (P = .01), Valsalva sinuses (P = .11), sinotubular junction (P = .001), and ascending aorta (P < .0001). The risks of reoperation (P = .86) and the onset of aortic regurgitation (P = .75) were comparable among the groups over the follow-up of 4.1 years. There was no difference in perioperative outcomes.
CONCLUSIONS
UAV is a separate unit characterized by a distinct hemodynamic pathology and generated aortopathy. It is not associated with a higher risk of reoperation or new onset of aortic regurgitation after the Ross procedure in the midterm postoperatively. At the current state, UAV remains acceptable for the Ross procedure.

Identifiants

pubmed: 35430219
pii: S0003-4975(22)00512-4
doi: 10.1016/j.athoracsur.2022.03.061
pii:
doi:

Types de publication

Observational Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

626-631

Informations de copyright

Copyright © 2023 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Auteurs

Jan Gofus (J)

Department of Cardiac Surgery, Charles University, Faculty of Medicine and University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.

Petr Fila (P)

Centre of Cardiovascular Surgery and Transplantation, Brno, Czech Republic; Department of Cardiovascular Surgery and Transplantation Brno, Faculty of Medicine, Masaryk University, Brno, Czech Republic. Electronic address: petr.fila@cktch.cz.

Martin Vobornik (M)

Department of Cardiac Surgery, Charles University, Faculty of Medicine and University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.

Jiri Ondrasek (J)

Centre of Cardiovascular Surgery and Transplantation, Brno, Czech Republic.

Petr Nemec (P)

Centre of Cardiovascular Surgery and Transplantation, Brno, Czech Republic; Department of Cardiovascular Surgery and Transplantation Brno, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

Jan Sterba (J)

Centre of Cardiovascular Surgery and Transplantation, Brno, Czech Republic; Department of Cardiovascular Surgery and Transplantation Brno, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

Eva Cermakova (E)

Department of Medical Biophysics, Charles University Faculty of Medicine, Hradec Kralove, Czech Republic.

Martin Tuna (M)

Department of Cardiac Surgery, Charles University, Faculty of Medicine and University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.

Jan Vojacek (J)

Department of Cardiac Surgery, Charles University, Faculty of Medicine and University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.

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