Sex- and age-related differences in autistic behaviours in children with neurofibromatosis type 1.
Age-related differences
Autism
Autistic
Children
Neurofibromatosis type 1
Sex differences
Journal
Journal of autism and developmental disorders
ISSN: 1573-3432
Titre abrégé: J Autism Dev Disord
Pays: United States
ID NLM: 7904301
Informations de publication
Date de publication:
Jul 2023
Jul 2023
Historique:
accepted:
10
04
2022
medline:
26
6
2023
pubmed:
22
4
2022
entrez:
21
4
2022
Statut:
ppublish
Résumé
This study investigated sex and age differences in autistic behaviours in children with neurofibromatosis type 1 (NF1) who scored within the clinical range on the Social Responsiveness Scale - Second Edition (T score ≥ 60). Thirty-four males and 28 females (3-16 years) were assessed with the Autism Diagnostic Observation Schedule - Second Edition and Autism Diagnostic Interview - Revised. Across both measures, males exhibited greater social communication deficits relative to females. Age-related abatement of social communication difficulties was observed for males but not females. Conversely, no sex differences were found for restricted/repetitive behaviours, which were stable over time for both males and females. The findings are discussed within the context of broader neurodevelopmental considerations that are common in NF1.
Identifiants
pubmed: 35445370
doi: 10.1007/s10803-022-05571-6
pii: 10.1007/s10803-022-05571-6
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2835-2850Subventions
Organisme : u.s. department of defense
ID : W81XWH-15-1-0619
Organisme : national health and medical research council
ID : national health and medical research council
Organisme : murdoch children's research institute
ID : murdoch children's research institute
Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Références
Achenbach, T. M., Dumenci, L., & Rescorla, L. A. (2003). DSM-oriented and empirically based approaches to constructing scales from the same item pools. Journal of Clinical Child and Adolescent Psychology, 32(3), 328–340. https://doi.org/10.1207/S15374424JCCP3203_02
doi: 10.1207/S15374424JCCP3203_02
pubmed: 12881022
Achenbach, T. M., Ivanova, M. Y., & Rescorla, L. A. (2017). Empirically based assessment and taxonomy of psychopathology for ages 1½–90 + years: Developmental, multi-informant, and multicultural findings. Comprehensive Psychiatry, 79, 4–18. https://doi.org/10.1016/j.comppsych.2017.03.006
doi: 10.1016/j.comppsych.2017.03.006
pubmed: 28356192
Achenbach, T. M., & Rescorla, L. A. (2000). Child Behavior Checklist for ages 1 1/2–5. ASEBA. University of Vermont
Achenbach, T. M., & Rescorla, L. A. (2001). Manual for the ASEBA school-age forms and profiles. University of Vermont, Research Center for Children, Youth, and Families
Aldridge, F. J., Gibbs, V. M., Schmidhofer, K., & Williams, M. (2012). Investigating the clinical usefulness of the Social Responsiveness Scale (SRS) in a tertiary level, autism spectrum disorder specific assessment clinic. Journal of Autism and Developmental Disorders, 42(2), 294–300. https://doi.org/10.1007/s10803-011-1242-9
doi: 10.1007/s10803-011-1242-9
pubmed: 21516433
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders-Fourth edition-Text revision (DSM-IV-TR). American Psychiatric Pub
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (DSM-5®). American Psychiatric Pub
Baio, J., Wiggins, L., Christensen, D. L., Maenner, M. J., Daniels, J., Warren, Z., et al. (2018). Prevalence of autism spectrum disorder among children aged 8 years - Autism and developmental disabilities monitoring network, 11 sites, United States, 2014. MMWR Surveillance Summaries, 67(6), 1–23. https://doi.org/10.15585/mmwr.ss6706a1
doi: 10.15585/mmwr.ss6706a1
pmcid: 5919599
Barbaro, J., & Dissanayake, C. (2017). Diagnostic stability of autism spectrum disorder in toddlers prospectively identified in a community-based setting: Behavioural characteristics and predictors of change over time. Autism, 21(7), 830–840. https://doi.org/10.1177/1362361316654084
doi: 10.1177/1362361316654084
pubmed: 27474118
Benjamini, Y., & Hochberg, Y. (1995). Controlling the false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society: Series B (Methodological), 57(1), 289–300. https://doi.org/10.1111/j.2517-6161.1995.tb02031.x
doi: 10.1111/j.2517-6161.1995.tb02031.x
Bent, C. A., Dissanayake, C., & Barbaro, J. (2015). Mapping the diagnosis of autism spectrum disorders in children aged under 7 years in Australia, 2010–2012. Medical Journal of Australia, 202(6), 317–320. https://doi.org/10.5694/mja14.00328
doi: 10.5694/mja14.00328
pubmed: 25832158
Bornstein, M. H., Hahn, C. S., Suwalsky, J. T., & Haynes, O. M. (2003). Socioeconomic status, parenting, and child development: The Hollingshead Four-Factor Index of Social Status and The Socioeconomic Index of Occupations. Lawrence Erlbaum Associates Publishers
Charman, T., Loth, E., Tillmann, J., Crawley, D., Wooldridge, C., Goyard, D., et al. (2017). The EU-AIMS Longitudinal European Autism Project (LEAP): Clinical characterisation. Molecular Autism, 8, 27. https://doi.org/10.1186/s13229-017-0145-9
doi: 10.1186/s13229-017-0145-9
pubmed: 28649313
pmcid: 5481972
Chisholm, A. K., Anderson, V. A., Pride, N. A., Malarbi, S., North, K. N., & Payne, J. M. (2018). Social function and autism spectrum disorder in children and adults with neurofibromatosis type 1: A systematic review and meta-analysis. Neuropsychology Review, 28(3), 317–340. https://doi.org/10.1007/s11065-018-9380-x
doi: 10.1007/s11065-018-9380-x
pubmed: 30097761
Chisholm, A. K., Haebich, K. M., Pride, N. A., Walsh, K. S., Lami, F., Ure, A., et al. (2022). Delineating the autistic phenotype in children with neurofibromatosis type 1. Molecular Autism, 13, 3. https://doi.org/10.1186/s13229-021-00481-3
doi: 10.1186/s13229-021-00481-3
pubmed: 34983638
pmcid: 8729013
Cholemkery, H., Kitzerow, J., Rohrmann, S., & Freitag, C. M. (2014). Validity of the social responsiveness scale to differentiate between autism spectrum disorders and disruptive behaviour disorders. European Child & Adolescent Psychiatry, 23(2), 81–93. https://doi.org/10.1007/s00787-013-0427-5
doi: 10.1007/s00787-013-0427-5
Cholemkery, H., Mojica, L., Rohrmann, S., Gensthaler, A., & Freitag, C. M. (2014). Can autism spectrum disorders and social anxiety disorders be differentiated by the Social Responsiveness Scale in children and adolescents? Journal of Autism and Developmental Disorders, 44(5), 1168–1182. https://doi.org/10.1007/s10803-013-1979-4
doi: 10.1007/s10803-013-1979-4
pubmed: 24682652
Christensen, D. L., Braun, K. V. N., Baio, J., Bilder, D., Charles, J., Constantino, J. N., et al. (2018). Prevalence and characteristics of autism spectrum disorder among children aged 8 years - Autism and developmental disabilities monitoring network, 11 sites, United States, 2012. MMWR Surveillance Summaries, 65(13), 1–23. https://doi.org/10.15585/mmwr.ss6513a1
doi: 10.15585/mmwr.ss6513a1
pmcid: 6237390
Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Lawrence Erlbaum Associates
Conners, C. K. (1997). Conners’ Rating Scales-Revised. Multi-Health Systems Inc
Conners, C. K. (2009). Conners 3rd edition. Multi-Health Systems Inc
Constantino, J. N., & Charman, T. (2016). Diagnosis of autism spectrum disorder: Reconciling the syndrome, its diverse origins, and variation in expression. Lancet Neurology, 15(3), 279–291. https://doi.org/10.1016/S1474-4422(15)00151-9
doi: 10.1016/S1474-4422(15)00151-9
pubmed: 26497771
Constantino, J. N., & Gruber, C. P. (2012). Social Responsiveness Scale, Second edition. Western Psychological Services
Conti-Ramsden, G., & Durkin, K. (2012). Language development and assessment in the preschool period. Neuropsychology Review, 22(4), 384–401. https://doi.org/10.1007/s11065-012-9208-z
doi: 10.1007/s11065-012-9208-z
pubmed: 22707315
Dean, M., Kasari, C., Shih, W., Frankel, F., Whitney, R., Landa, R., et al. (2014). The peer relationships of girls with ASD at school: Comparison to boys and girls with and without ASD. Journal of Child Psychology and Psychiatry, 55(11), 1218–1225. https://doi.org/10.1111/jcpp.12242
doi: 10.1111/jcpp.12242
pubmed: 25039696
Eijk, S., Mous, S. E., Dieleman, G. C., Dierckx, B., Rietman, A. B., de Nijs, P. F. A., et al. (2018). Autism spectrum disorder in an unselected cohort of children with neurofibromatosis type 1 (NF1). Journal of Autism and Developmental Disorders, 48(7), 2278–2285. https://doi.org/10.1007/s10803-018-3478-0
doi: 10.1007/s10803-018-3478-0
pubmed: 29423604
pmcid: 5995999
Evans, D. G., Howard, E., Giblin, C., Clancy, T., Spencer, H., Huson, S. M., et al. (2010). Birth incidence and prevalence of tumor-prone syndromes: Estimates from a UK family genetic register service. American Journal of Medical Genetics. Part A, 152A(2), 327–332. https://doi.org/10.1002/ajmg.a.33139
doi: 10.1002/ajmg.a.33139
pubmed: 20082463
Ferner, R. E. (2007). Neurofibromatosis 1. European Journal of Human Genetics, 15(2), 131–138. https://doi.org/10.1038/sj.ejhg.5201676
doi: 10.1038/sj.ejhg.5201676
pubmed: 16957683
Garg, S., & Green, J. (2018). Studying child development in genetic models of ASD. Progress in brain research (241 vol., pp. 159–192). Elsevier
Garg, S., Green, J., Leadbitter, K., Emsley, R., Lehtonen, A., Evans, D. G., et al. (2013). Neurofibromatosis type 1 and autism spectrum disorder. Pediatrics, 132(6), e1642–1648. https://doi.org/10.1542/peds.2013-1868
doi: 10.1542/peds.2013-1868
pubmed: 24190681
Garg, S., Heuvelman, H., Huson, S., Tobin, H., & Green, J. (2016). Sex bias in autism spectrum disorder in neurofibromatosis type 1. Journal of Neurodevelopmental Disorders, 8(26), 1–8. https://doi.org/10.1186/s11689-016-9159-4
doi: 10.1186/s11689-016-9159-4
Garg, S., Lehtonen, A., Huson, S. M., Emsley, R., Trump, D., Evans, D. G., et al. (2013). Autism and other psychiatric comorbidity in neurofibromatosis type 1: Evidence from a population-based study. Developmental Medicine & Child Neurology, 55(2), 139–145. https://doi.org/10.1111/dmcn.12043
doi: 10.1111/dmcn.12043
Garg, S., Plasschaert, E., Descheemaeker, M. J., Huson, S., Borghgraef, M., Vogels, A., et al. (2015). Autism spectrum disorder profile in neurofibromatosis type 1. Journal of Autism and Developmental Disorders, 45(6), 1649–1657. https://doi.org/10.1007/s10803-014-2321-5
doi: 10.1007/s10803-014-2321-5
pubmed: 25475362
Geoffray, M. M., Falissard, B., Green, J., Kerr, B., Evans, D. G., Huson, S., et al. (2021). Autism spectrum disorder symptom profile across the RASopathies. Frontiers in Psychiatry, 11:585700. https://doi.org/10.3389/fpsyt.2020.585700
Gotham, K., Pickles, A., & Lord, C. (2012). Trajectories of autism severity in children using standardized ADOS scores. Pediatrics, 130(5), e1278–e1284. https://doi.org/10.1542/peds.2011-3668
doi: 10.1542/peds.2011-3668
pubmed: 23090336
pmcid: 3483889
Griffiths, D. L., Farrell, L. J., Waters, A. M., & White, S. W. (2017). ASD traits among youth with obsessive-compulsive disorder. Child Psychiatry & Human Development, 48(6), 911–921. https://doi.org/10.1007/s10578-017-0714-3
doi: 10.1007/s10578-017-0714-3
Gutmann, D. H., Ferner, R. E., Listernick, R. H., Korf, B. R., Wolters, P. L., & Johnson, K. J. (2017). Neurofibromatosis type 1. Nature Reviews. Disease Primers, 3, 17004. https://doi.org/10.1038/nrdp.2017.4
doi: 10.1038/nrdp.2017.4
pubmed: 28230061
Haebich, K. M., Pride, N. A., Walsh, K. S., Chisholm, A., Rouel, M., Maier, A., et al. (2019). Understanding autism spectrum disorder and social functioning in children with neurofibromatosis type 1: Protocol for a cross-sectional multimodal study. BMJ Open, 9(9), e030601. https://doi.org/10.1136/bmjopen-2019-030601
doi: 10.1136/bmjopen-2019-030601
pubmed: 31558455
pmcid: 6773330
Hall, J. A. (2011). Sex differences in friendship expectations: A meta-analysis. Journal of Social and Personal Relationships, 28(6), 723–747. https://doi.org/10.1177/0265407510386192
doi: 10.1177/0265407510386192
Havdahl, K. A., Bal, V. H., Huerta, M., Pickles, A., Øyen, A. S., Stoltenberg, C., et al. (2016). Multidimensional influences on autism symptom measures: Implications for use in etiological research. Journal of the American Academy of Child & Adolescent Psychiatry, 55(12), 1054–1063. https://doi.org/10.1016/j.jaac.2016.09.490
doi: 10.1016/j.jaac.2016.09.490
Hinkle, D. E., Wiersma, W., & Jurs, S. G. (2003). Applied statistics for the behavioral sciences (663 vol.). Houghton Mifflin College Division
Hull, L., Mandy, W., & Petrides, K. (2017). Behavioural and cognitive sex/gender differences in autism spectrum condition and typically developing males and females. Autism, 21(6), 706–727. https://doi.org/10.1177/1362361316669087
doi: 10.1177/1362361316669087
pubmed: 28749232
Hus, V., Bishop, S., Gotham, K., Huerta, M., & Lord, C. (2013). Factors influencing scores on the social responsiveness scale. Journal of Child Psychology and Psychiatry, 54(2), 216–224. https://doi.org/10.1111/j.1469-7610.2012.02589.x
doi: 10.1111/j.1469-7610.2012.02589.x
pubmed: 22823182
Hus, V., Gotham, K., & Lord, C. (2014). Standardizing ADOS domain scores: Separating severity of social affect and restricted and repetitive behaviors. Journal of Autism and Developmental Disorders, 44(10), 2400–2412. https://doi.org/10.1007/s10803-012-1719-1
doi: 10.1007/s10803-012-1719-1
pubmed: 23143131
pmcid: 3612387
Hyman, S. L., Shores, A., & North, K. N. (2005). The nature and frequency of cognitive deficits in children with neurofibromatosis type 1. Neurology, 65(7), 1037–1044. https://doi.org/10.1212/01.wnl.0000179303.72345.ce
doi: 10.1212/01.wnl.0000179303.72345.ce
pubmed: 16217056
Jones, R. M., Risi, S., Wexler, D., Anderson, D., Corsello, C., Pickles, A., et al. (2015). How interview questions are placed in time influences caregiver description of social communication symptoms on the ADI-R. Journal of Child Psychology and Psychiatry, 56(5), 577–585. https://doi.org/10.1111/jcpp.12325
doi: 10.1111/jcpp.12325
pubmed: 25243378
Kaat, A. J., Shui, A. M., Ghods, S. S., Farmer, C. A., Esler, A. N., Thurm, A., et al. (2021). Sex differences in scores on standardized measures of autism symptoms: A multisite integrative data analysis. Journal of Child Psychology and Psychiatry, 62(1), 97–106. https://doi.org/10.1111/jcpp.13242
doi: 10.1111/jcpp.13242
pubmed: 32314393
Korf, B. R. (2013). Neurofibromatosis. In O. Dulac, M. Lassonde, & H. B. Sarnat (Eds.), Handbook of clinical neurology (111 vol., pp. 333–340). Elsevier
Korkman, M., Kirk, U., & Kemp, S. (2007). The NEPSY-2nd edition (NEPSY II). Clinical and interpretive manual. TX: Psychological Corporation
Lai, M. C., Baron-Cohen, S., & Buxbaum, J. D. (2015). Understanding autism in the light of sex/gender. Molecular Autism, 6, 24. https://doi.org/10.1186/s13229-015-0021-4
doi: 10.1186/s13229-015-0021-4
pubmed: 25973161
pmcid: 4429357
Lai, M. C., Lombardo, M. V., & Baron-Cohen, S. (2014). Autism. The Lancet, 383(9920), 896–910. http://dx.doi.org10.1016/S0140-6736(13)61539-1
Le Couteur, A., Lord, C., & Rutter, M. (2003). The Autism Diagnostic Interview-Revised (ADI-R). Los Angeles, CA: Western Psychological Services
Lehtonen, A., Howie, E., Trump, D., & Huson, S. M. (2013). Behaviour in children with neurofibromatosis type 1: Cognition, executive function, attention, emotion, and social competence. Developmental Medicine & Child Neurology, 55(2), 111–125. https://doi.org/10.1111/j.1469-8749.2012.04399.x
doi: 10.1111/j.1469-8749.2012.04399.x
Leman, P. J., & Tenenbaum, H. R. (2011). Practising gender: Children’s relationships and the development of gendered behaviour and beliefs. The British Journal of Developmental Psychology, 29(Pt 2), 153–157. https://doi.org/10.1111/j.2044-835X.2011.02032.x
doi: 10.1111/j.2044-835X.2011.02032.x
pubmed: 21592145
Levy, S. E., Giarelli, E., Lee, L. C., Schieve, L. A., Kirby, R. S., Cunniff, C., et al. (2010). Autism spectrum disorder and co-occurring developmental, psychiatric, and medical conditions among children in multiple populations of the United States. Journal of Developmental & Behavioral Pediatrics, 31(4), 267–275. https://doi.org/10.1097/DBP.0b013e3181d5d03b
doi: 10.1097/DBP.0b013e3181d5d03b
Linstead, E., Dixon, D. R., Hong, E., Burns, C. O., French, R., Novack, M. N., et al. (2017). An evaluation of the effects of intensity and duration on outcomes across treatment domains for children with autism spectrum disorder. Translational Psychiatry, 7(9), e1234. https://doi.org/10.1038/tp.2017.207
doi: 10.1038/tp.2017.207
pubmed: 28925999
pmcid: 5639250
Loomes, R., Hull, L., & Mandy, W. P. L. (2017). What is the male-to-female ratio in autism spectrum disorder? A systematic review and meta-analysis. Journal of the American Academy of Child & Adolescent Psychiatry, 56(6), 466–474. https://doi.org/10.1016/j.jaac.2017.03.013
doi: 10.1016/j.jaac.2017.03.013
Lord, C., Bishop, S., & Anderson, D. (2015). Developmental trajectories as autism phenotypes. American Journal of Medical Genetics, Part C, 169(2), 198–208. https://doi.org/10.1002/ajmg.c.31440
doi: 10.1002/ajmg.c.31440
Lord, C., & Jones, R. M. (2012). Annual research review: Re-thinking the classification of autism spectrum disorders. Journal of Child Psychology and Psychiatry, 53(5), 490–509. https://doi.org/10.1111/j.1469-7610.2012.02547.x
doi: 10.1111/j.1469-7610.2012.02547.x
pubmed: 22486486
Lord, C., Rutter, M., DiLavore, P., Risi, S., Gotham, K., & Bishop, S. (2012). Autism Diagnostic Observation Schedule-2nd edition (ADOS-2). Los Angeles, CA: Western Psychological Corporation
Mahendiran, T., Dupuis, A., Crosbie, J., Georgiades, S., Kelley, E., Liu, X., et al. (2019). Sex differences in social adaptive function in autism spectrum disorder and attention-deficit hyperactivity disorder. Frontiers in Psychiatry, 10, 607. https://doi.org/10.3389/fpsyt.2019.00607
doi: 10.3389/fpsyt.2019.00607
pubmed: 31572228
pmcid: 6751776
May, T., Brignell, A., Hawi, Z., Brereton, A., Tonge, B., Bellgrove, M., et al. (2018). Trends in the overlap of autism spectrum disorder and attention deficit hyperactivity disorder: Prevalence, clinical management, language and genetics. Current Developmental Disorders Reports, 5(1), 49–57. https://doi.org/10.1007/s40474-018-0131-8
doi: 10.1007/s40474-018-0131-8
May, T., Brignell, A., & Williams, K. (2020). Autism spectrum disorder prevalence in children aged 12–13 years from the Longitudinal Study of Australian Children. Autism Research, 13(5), 821–827. https://doi.org/10.1002/aur.2286
doi: 10.1002/aur.2286
pubmed: 32124539
McDonald, J. (2014). Handbook of biological statistics (3rd ed.). Sparky House Publishing
McGovern, C. W., & Sigman, M. (2005). Continuity and change from early childhood to adolescence in autism. Journal of Child Psychology and Psychiatry, 46(4), 401–408. https://doi.org/10.1111/j.1469-7610.2004.00361.x
doi: 10.1111/j.1469-7610.2004.00361.x
pubmed: 15819649
McLennan, J. D., Lord, C., & Schopler, E. (1993). Sex differences in higher functioning people with autism. Journal of Autism and Developmental Disorders, 23(2), 217–227
doi: 10.1007/BF01046216
pubmed: 8331044
Miodovnik, A., Harstad, E., Sideridis, G., & Huntington, N. (2015). Timing of the diagnosis of attention-deficit/hyperactivity disorder and autism spectrum disorder. Pediatrics, 136(4), e830–837. https://doi.org/10.1542/peds.2015-1502
doi: 10.1542/peds.2015-1502
pubmed: 26371198
Morotti, H., Mastel, S., Keller, K., Barnard, R. A., Hall, T., O’Roak, B. J., et al. (2019). The association of neurofibromatosis and autism symptomatology is confounded by behavioral problems. medRxiv. https://doi.org/10.1101/2019.12.20.19015420
doi: 10.1101/2019.12.20.19015420
Morris, S. M., Acosta, M. T., Garg, S., Green, J., Huson, S., Legius, E., et al. (2016). Disease burden and symptom structure of autism in neurofibromatosis type 1: A study of the International NF1-ASD Consortium Team (INFACT). JAMA Psychiatry, 73(12), 1276–1284. https://doi.org/10.1001/jamapsychiatry.2016.2600
doi: 10.1001/jamapsychiatry.2016.2600
pubmed: 27760236
pmcid: 5298203
Naar-King, S., Ellis, D. A., Frey, M. A., & Ondersma, M. L. (2003). Assessing children’s well-being: A handbook of measures. Routledge
Neurofibromatosis (1988). Neurofibromatosis. Conference statement. National Institutes of Health Consensus Development Conference. Archives of Neurology, 45(5), 575–578
Noll, R. B., Reiter-Purtill, J., Moore, B. D., Schorry, E. K., Lovell, A. M., Vannatta, K., et al. (2007). Social, emotional, and behavioral functioning of children with NF1. American Journal of Medical Genetics. Part A, 143A(19), 2261–2273. https://doi.org/10.1002/ajmg.a.31923
doi: 10.1002/ajmg.a.31923
pubmed: 17726688
Payne, J. M., Haebich, K. M., MacKenzie, R., Walsh, K. S., Hearps, S. J., Coghill, D., et al. (2021). Cognition, ADHD symptoms, and functional impairment in children and adolescents with neurofibromatosis type 1. Journal of Attention Disorders, 25(8), 1177–1186. https://doi.org/10.1177%2F1087054719894384
doi: 10.1177/1087054719894384
pubmed: 31838937
Payne, J. M., Pride, N., & North, K. N. (2013). Cognition and behaviour in neurofibromatosis type 1: Pathogenesis and emerging therapies. In M. A. Karajannis, & J. Allen (Eds.), Neurofibromatosis type 1 (pp. 117–146). Nova Science Publishers, Inc
Payne, J. M., Walsh, K. S., Pride, N. A., Haebich, K. M., Maier, A., Chisholm, A., et al. (2020). Social skills and autism spectrum disorder symptoms in children with neurofibromatosis type 1: Evidence for clinical trial outcomes. Developmental Medicine & Child Neurology, 62(7), 813–819. https://doi.org/10.1111/dmcn.14517
doi: 10.1111/dmcn.14517
Plasschaert, E., Descheemaeker, M. J., Van Eylen, L., Noens, I., Steyaert, J., & Legius, E. (2015). Prevalence of autism spectrum disorder symptoms in children with neurofibromatosis type 1. American Journal of Medical Genetics, Part B, 168(1), 72–80. https://doi.org/10.1002/ajmg.b.32280
doi: 10.1002/ajmg.b.32280
Plasschaert, E., Van Eylen, L., Descheemaeker, M. J., Noens, I., Legius, E., & Steyaert, J. (2016). Executive functioning deficits in children with neurofibromatosis type 1: The influence of intellectual and social functioning. American Journal of Medical Genetics. Part B, 171B, 348–362. https://doi.org/10.1002/ajmg.b.32414
doi: 10.1002/ajmg.b.32414
R Core Team (2020). R: A language and environment for statistical computing: R Foundation for Statistical Computing. Retrieved from http://www.R-project.org
Ratto, A. B., Kenworthy, L., Yerys, B. E., Bascom, J., Wieckowski, A. T., White, S. W., et al. (2018). What about the girls? Sex-based differences in autistic traits and adaptive skills. Journal of Autism and Developmental Disorders, 48(5), 1698–1711. https://doi.org/10.1007/s10803-017-3413-9
doi: 10.1007/s10803-017-3413-9
pubmed: 29204929
pmcid: 5925757
Reindal, L., Nærland, T., Weidle, B., Lydersen, S., Andreassen, O. A., & Sund, A. M. (2021). Structural and pragmatic language impairments in children evaluated for autism spectrum disorder (ASD). Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-020-04853-1
doi: 10.1007/s10803-020-04853-1
pubmed: 33515169
pmcid: 9944009
Richler, J., Huerta, M., Bishop, S. L., & Lord, C. (2010). Developmental trajectories of restricted and repetitive behaviors and interests in children with autism spectrum disorders. Development and Psychopathology, 22(1), 55–69. https://doi.org/10.1017/S0954579409990265
doi: 10.1017/S0954579409990265
pubmed: 20102647
pmcid: 2893549
Rose, A. J., & Rudolph, K. D. (2006). A review of sex differences in peer relationship processes: Potential trade-offs for the emotional and behavioral development of girls and boys. Psychological Bulletin, 132(1), 98–131. https://doi.org/10.1037/0033-2909.132.1.98
doi: 10.1037/0033-2909.132.1.98
pubmed: 16435959
pmcid: 3160171
Rutter, M., Le Couteur, A., & Lord, C. (2003). Autism Diagnostic Interview-Revised. WPS edition. Los Angeles: Western Psychological Services
Rynkiewicz, A., Schuller, B., Marchi, E., Piana, S., Camurri, A., Lassalle, A., et al. (2016). An investigation of the ‘female camouflage effect’ in autism using a computerized ADOS-2 and a test of sex/gender differences. Molecular Autism, 7, 10. https://doi.org/10.1186/s13229-016-0073-0
doi: 10.1186/s13229-016-0073-0
pubmed: 26798446
pmcid: 4721191
Semel, E., Wiig, E. H., & Secord, W. A. (2003). Clinical Evaluation of Language Fundamentals-Fourth edition. Harcourt Assessment
Shattuck, P. T., Seltzer, M. M., Greenberg, J. S., Orsmond, G. I., Bolt, D., Kring, S., et al. (2007). Change in autism symptoms and maladaptive behaviors in adolescents and adults with an autism spectrum disorder. Journal of Autism and Developmental Disorders, 37(9), 1735–1747. https://doi.org/10.1007/s10803-006-0307-7
doi: 10.1007/s10803-006-0307-7
pubmed: 17146700
Solomon, M., Miller, M., Taylor, S. L., Hinshaw, S. P., & Carter, C. S. (2012). Autism symptoms and internalizing psychopathology in girls and boys with autism spectrum disorders. Journal of Autism and Developmental Disorders, 42(1), 48–59. https://doi.org/10.1007/s10803-011-1215-z
doi: 10.1007/s10803-011-1215-z
pubmed: 21442362
Szatmari, P., Georgiades, S., Duku, E., Bennett, T. A., Bryson, S., Fombonne, E., et al. (2015). Developmental trajectories of symptom severity and adaptive functioning in an inception cohort of preschool children with autism spectrum disorder. JAMA Psychiatry, 72(3), 276–283. https://doi.org/10.1001/jamapsychiatry.2014.2463
doi: 10.1001/jamapsychiatry.2014.2463
pubmed: 25629657
Taylor, J. L., & Seltzer, M. M. (2010). Changes in the autism behavioral phenotype during the transition to adulthood. Journal of Autism and Developmental Disorders, 40(12), 1431–1446. https://doi.org/10.1007/s10803-010-1005-z
doi: 10.1007/s10803-010-1005-z
pubmed: 20361245
pmcid: 2910794
Tierney, S., Burns, J., & Kilbey, E. (2016). Looking behind the mask: Social coping strategies of girls on the autistic spectrum. Research in Autism Spectrum Disorders, 23, 73–83. https://doi.org/10.1016/j.rasd.2015.11.013
doi: 10.1016/j.rasd.2015.11.013
Van Wijngaarden-Cremers, P. J., van Eeten, E., Groen, W. B., Van Deurzen, P. A., Oosterling, I. J., & Van der Gaag, R. J. (2014). Gender and age differences in the core triad of impairments in autism spectrum disorders: A systematic review and meta-analysis. Journal of Autism and Developmental Disorders, 44(3), 627–635. https://doi.org/10.1007/s10803-013-1913-9
doi: 10.1007/s10803-013-1913-9
pubmed: 23989936
Venker, C. E., Ray-Subramanian, C. E., Bolt, D. M., & Weismer, E., S (2014). Trajectories of autism severity in early childhood. Journal of Autism and Developmental Disorders, 44(3), 546–563. https://doi.org/10.1007/s10803-013-1903-y
doi: 10.1007/s10803-013-1903-y
pubmed: 23907710
pmcid: 3909724
Viskochil, D. (2021). Neurofibromatosis type 1. In J. C. Carey, A. Battaglia, D. Viskochil, & S. B. Cassidy (Eds.), Cassidy and Allanson’s management of genetic syndromes (Fourth ed., pp. 629–649). John Wiley & Sons, Inc.
Visser, J. C., Rommelse, N. N., Lappenschaar, M., Servatius-Oosterling, I. J., Greven, C. U., & Buitelaar, J. K. (2017). Variation in the early trajectories of autism symptoms is related to the development of language, cognition, and behavior problems. Journal of the American Academy of Child & Adolescent Psychiatry, 56(8), 659–668. https://doi.org/10.1016/j.jaac.2017.05.022
doi: 10.1016/j.jaac.2017.05.022
Vivanti, G., & Volkmar, F. R. (2020). National guideline for the assessment and diagnosis of autism spectrum disorders in Australia. Journal of Autism and Developmental Disorders, 50, 2252–2254. https://doi.org/10.1007/s10803-019-03937-x
doi: 10.1007/s10803-019-03937-x
Wechsler, D. (2012). Wechsler Preschool and Primary Scale of Intelligence-4th edition (WPPSI-IV). Pearson
Wechsler, D. (2014). Wechsler Intelligence Scale for Children-5th edition (WISC-V). Pearson
Werling, D. M., & Geschwind, D. H. (2013). Sex differences in autism spectrum disorders. Current Opinion in Neurology, 26(2), 146–153. https://doi.org/10.1097/WCO.0b013e32835ee548
doi: 10.1097/WCO.0b013e32835ee548
pubmed: 23406909
pmcid: 4164392
Wiig, E. H., Secord, W., & Semel, E. (2006). Clinical Evaluation of Language Fundamentals-Preschool-Second edition (Australian). Harcourt Assessment
Zwaigenbaum, L., Bauman, M. L., Choueiri, R., Kasari, C., Carter, A., Granpeesheh, D., et al. (2015). Early intervention for children with autism spectrum disorder under 3 years of age: Recommendations for practice and research. Pediatrics, 136(Supplement 1), S60–S81. https://doi.org/10.1542/peds.2014-3667E
doi: 10.1542/peds.2014-3667E
pubmed: 26430170
pmcid: 9923898